LOCUS BC009354 3034 bp mRNA linear HUM 22-AUG-2008
DEFINITION Homo sapiens DENN/MADD domain containing 5A, mRNA (cDNA clone
IMAGE:4298580), partial cds.
ACCESSION BC009354
VERSION BC009354.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3034)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3034)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC009354.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: m Column: 22.
FEATURES Location/Qualifiers
source 1..3034
/db_xref="H-InvDB:HIT000034301"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4298580"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..3034
/gene="DENND5A"
/db_xref="GeneID:23258"
/db_xref="HGNC:HGNC:19344"
CDS <1..2849
/gene="DENND5A"
/codon_start=3
/product="DENND5A protein"
/protein_id="AAH09354.2"
/db_xref="GeneID:23258"
/db_xref="HGNC:HGNC:19344"
/translation="VYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLC
FVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGNLHCSESASKLKRLRAS
ELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDLK
VQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDK
ASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLN
VRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKIGQGKYEPGFFPKL
QSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARTMGSTIR
QPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEE
NTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTSGILLDSE
RRKSDASSLMPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLL
SDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPS
KKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLY
AKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRT
PPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLL
CGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRA
RNFCRFVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVAL
IKDHTLVNSLIRVLQTLQEFNITLETSLVKGIDI"
BASE COUNT 838 a 732 c 760 g 704 t
ORIGIN
1 atgtctatgt ccctattctc ccagcttctc tcctgcattt cttagatgct cctgttccat
61 acctgatggg tttgcattcc aatggcctgg atgaccggtc aaagctggag ctgcctcaag
121 aggctaacct ctgctttgtg gacattgaca accacttcat tgagttgcca gaggacttgc
181 cacagttccc caacaaattg gagtttgtcc aggaagtctc tgagattctc atggcatttg
241 gaattccccc tgaagggaat cttcattgca gtgagagtgc ctccaagctg aagaggctgc
301 gggcctctga gcttgtctcg gacaagagga atgggaacat tgctggctcc cctttgcatt
361 cctacgagct tcttaaggag aatgaaacta ttgcccggct gcaagccttg gtcaagagaa
421 ctggggtgag cctggaaaag ttggaagtgc gtgaagaccc cagcagcaat aaggatctca
481 aagttcagtg tgatgaagaa gaactcagga tttaccagct aaacattcag atccgggaag
541 tttttgcaaa tcgtttcact cagatgtttg cagattatga ggtgtttgtc atccaaccca
601 gccaggataa ggaatcctgg tttaccaaca gggagcaaat gcaaaacttt gataaagcat
661 cttttctgtc agatcagcct gagccctacc tgcccttcct ctcaagattc ctggagaccc
721 agatgtttgc atctttcatt gacaacaaaa taatgtgtca tgatgatgat gataaagacc
781 ctgtactccg ggtatttgat tcccgagttg acaagatcag gctgttgaat gttcggacac
841 ctactctccg tacatccatg taccagaagt gtaccactgt ggatgaagca gagaaagcaa
901 ttgagctgcg tctggcaaaa attgaccata ctgcaattca cccacattta cttgacatga
961 agattggaca agggaaatat gagccgggct tcttccctaa gctgcagtct gatgtacttt
1021 ccactgggcc agccagcaac aagtggacga aaaggaatgc ccctgcccag tggaggcgga
1081 aagatcggca gaagcagcac acagaacacc tgcgtttaga taatgaccag agggagaagt
1141 acatccagga agccaggact atgggcagca ctatccgcca gcccaaactg tccaacctct
1201 ctccatcagt gattgcccag accaattgga agtttgtaga gggcctgctg aaggaatgcc
1261 gcaataagac caagaggatg ctggtggaaa agatgggccg agaagctgtg gagctagggc
1321 atggggaggt gaacatcaca ggggtggaag agaacaccct gattgccagc ctttgtgatc
1381 tcctggaaag gatctggagt catggactac aagtgaaaca ggggaaatca gccttatggt
1441 cccacctgtt acattatcag gacaaccggc agagaaaact cacatcagga agcctcagta
1501 cctcaggaat acttcttgat tcagaacgta ggaagtctga tgccagctca ctcatgcctc
1561 ccctgaggat ctccctgatt caggatatga ggcacatcca gaacatcggg gaaatcaaga
1621 ctgatgtggg aaaggccaga gcatgggtgc gactgtccat ggaaaaaaag ttactttcca
1681 gacacctgaa gcagctcctc tcagaccatg agctcaccaa aaagttatat aagcgctatg
1741 ccttcctgcg ctgtgatgac gagaaggagc agttcctcta tcacctcctg tctttcaatg
1801 ccgtcgatta cttttgcttc accaatgtct tcacaactat cctgatcccg taccacattc
1861 tgatcgtacc aagcaagaag ctggggggct ccatgttcac tgccaaccca tggatctgta
1921 tatcaggaga attgggtgag acacagatca tgcagattcc caggaatgtg ctagagatga
1981 ccttcgagtg ccagaacttg gggaagctta ctactgtcca gattggccat gataactctg
2041 ggctgtatgc caaatggctg gtggagtatg tgatggtcag gaatgagatc acaggacata
2101 cctacaagtt cccgtgtggc cggtggttag ggaagggcat ggatgatgga agcctggagc
2161 ggatcctagt tggggagctg ctcacatccc agcctgaggt ggatgagagg ccatgccgga
2221 ccccgccgct gcagcagtcc cccagtgtca tccggaggct tgttaccatc tcacccaaca
2281 acaagcccaa gctgaacact gggcagatcc aggagtccat cggggaggca gtcaatggca
2341 ttgtgaagca cttccataag cctgagaaag agcgaggcag tctgacgctg ttgctctgtg
2401 gagagtgtgg ccttgtctcg gccttggaac aggctttcca gcatggattt aaatcgcccc
2461 ggctcttcaa aaatgtcttc atttgggatt tcctggaaaa agcacaaacc tattatgaga
2521 cattagagaa gaatgaagta gtccctgagg aaaactggca tacaagagcc cggaacttct
2581 gccgatttgt cactgcaatc aacaatactc cccggaacat cggcaaggat ggcaagtttc
2641 agatgctggt gtgcttggga gccagagatc acctcctaca ccactggatt gccctgctgg
2701 ctgactgccc catcactgca cacatgtatg aggatgtggc actgatcaaa gaccatacac
2761 ttgtcaattc cttgattcgt gtgctgcaga cattgcagga gttcaacatc acgctggaga
2821 cgtcccttgt caagggcatc gacatctgac ctcccagcac cagccagcag caggactgag
2881 aaagactcac cctgcagctc tgaccttttt tcccaaaggg acttaagcga ttgtgcagga
2941 gtaggagaca aaatgtacac tcactgtaaa aagaaaacta gaggattttt ggaataaata
3001 atctatttta gagtttaaaa aaaaaaaaaa aaaa
//