LOCUS BC009343 2875 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens plexin A2, mRNA (cDNA clone IMAGE:4130636), partial
cds.
ACCESSION BC009343
VERSION BC009343.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2875)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2875)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC009343.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: k Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2875
/db_xref="H-InvDB:HIT000087260"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4130636"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2875
/gene="PLXNA2"
/gene_synonym="FLJ11751"
/gene_synonym="KIAA0463"
/gene_synonym="OCT"
/gene_synonym="PLXN2"
/db_xref="GeneID:5362"
/db_xref="MIM:601054"
CDS <1..2433
/gene="PLXNA2"
/gene_synonym="FLJ11751"
/gene_synonym="KIAA0463"
/gene_synonym="OCT"
/gene_synonym="PLXN2"
/codon_start=1
/product="PLXNA2 protein"
/protein_id="AAH09343.2"
/db_xref="GeneID:5362"
/db_xref="MIM:601054"
/translation="VVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQS
LLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIG
ETPCAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAA
GGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINE
LTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLIN
NKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLE
NKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDA
ITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDTITQVKEKILD
AVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDR
SVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVK
VWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLLSTVHRGSA
LPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSI
TDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAI
SDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYK
VEQLINAMSIES"
misc_feature 175..429
/gene="PLXNA2"
/gene_synonym="FLJ11751"
/gene_synonym="KIAA0463"
/gene_synonym="OCT"
/gene_synonym="PLXN2"
/note="TIG; Region: IPT/TIG domain. This family consists
of a domain that has an immunoglobulin like fold. These
domains are found in cell surface receptors such as Met
and Ron as well as in intracellular transcription factors
where it is involved in DNA binding. CAUTION: This family
does not currently recognise a significant number of
members"
/db_xref="CDD:pfam01833"
BASE COUNT 703 a 831 c 767 g 574 t
ORIGIN
1 gtggtgtgta aagttgtgaa cacaaccacc ctcacctgcc tggcaccctc tctgaccacg
61 gactaccgcc ctggcctgga cactgtggaa cgcccagatg agtttggatt tgtctttaac
121 aatgtccaat ccttgctaat ttacaacgac accaagttta tctactaccc caacccgacc
181 tttgaactgc ttagccctac tggagtcttg gatcaaaagc caggatcgcc catcattctg
241 aagggcaaaa acctctgccc tcctgcctct ggaggggcca aactcaacta cactgtgctc
301 atcggagaga ccccttgtgc tgtcaccgta tctgagaccc agcttctctg cgagcctccc
361 aacctcaccg ggcagcacaa ggtcatggtt cacgtgggcg ggatggtgtt ctcgcctggc
421 tcggtgagtg tcatctcaga cagcttgctg accctgccag ccatcgtcag catcgcggcc
481 ggcggcagcc tcctcctcat catcgtcatc atcgtcctca ttgcctacaa gcgcaagtct
541 cgagaaaatg acctcactct caagcggctg caaatgcaga tggacaatct ggagtcccgt
601 gtggctttgg agtgcaagga agcttttgct gagctccaga cggatatcaa tgagttgacc
661 agtgacctgg accgctcagg aatcccttac ctggactatc gtacctacgc tatgcgagtc
721 ctgttcccgg gcatcgagga ccaccccgtc ctgcgggagc tggaggtaca aggaaacggg
781 cagcagcacg tggagaaggc cctgaagctc tttgcccagc tcatcaacaa caaggtgttc
841 ctgctgacct tcatccgcac cctggagctg cagcgcagtt tctccatgcg cgaccggggc
901 aacgtggctt cgctcatcat gaccggcctg cagggccgcc tggaatatgc cactgatgtc
961 ctcaagcagc tgctctctga cctcatcgat aagaacctgg agaacaagaa ccaccccaag
1021 ctgctactcc ggaggacaga gtctgtggct gaaaagatgc tgaccaattg gttcgccttc
1081 ctcctgcaca agttcctaaa ggagtgcgca ggggagccac tcttcatgct atactgtgcc
1141 atcaagcagc agatggagaa gggccccatt gatgccatca cgggcgaggc ccgctactcc
1201 ctgagcgagg acaagctcat ccggcagcag atcgagtaca agaccctgat cctgaactgc
1261 gtcaaccctg acaacgagaa cagtccagag atcccagtga aggtgttaaa ctgtgacacc
1321 atcacacagg tcaaggagaa gattcttgat gccgtgtata agaatgtgcc ctattcccag
1381 cggccgaggg cagtggacat ggacttggag tggcgccaag gccggatcgc ccgggtcgtg
1441 ctgcaagatg aggacatcac caccaagatt gagggtgact ggaagcggct caacacactg
1501 atgcattatc aggtgtcaga caggtcggtg gtggctctgg tccccaaaca gacctcctcc
1561 tacaacatcc ctgcctctgc cagcatctcc cggacgtcca tcagcagata cgactcctcc
1621 ttcaggtata cgggcagccc cgacagcctg cggtcccggg ccccgatgat caccccagac
1681 ctggaaagtg gggtcaaggt gtggcatctg gtgaagaacc atgaccacgg tgaccagaag
1741 gagggtgacc ggggcagcaa gatggtgtcc gagatctacc tgacccggct actggccacc
1801 aagggcaccc tgcagaagtt tgtggacgac ttgtttgaga ccttgctcag cactgtgcac
1861 cggggcagcg ctctccccct ggccatcaag tacatgtttg atttcctaga tgagcaggca
1921 gacaggcaca gcatccatga cacagatgtg cggcacacct ggaaaagcaa ctgcctccct
1981 ctgcgcttct gggtgaacgt gattaagaac ccccagttcg tgtttgacat ccacaagggc
2041 agcatcacgg acgcctgcct ctctgtggtg gcccagacct tcatggactc ttgttcaacg
2101 tcagagcacc ggctgggcaa ggactccccc tccaacaagc tgctctatgc caaggacatc
2161 cccagctaca agagctgggt ggagagatac tacgcagaca tcgccaagct cccagccatc
2221 agtgaccagg acatgaatgc ctacctcgcc gagcagtccc gcctgcacgc cgtggagttc
2281 aacatgctga gtgccctcaa tgagatctac tcctatgtca gcaagtatag tgaggagctc
2341 atcggggccc tagagcagga tgagcaggca cggcggcagc ggctggctta taaggtggag
2401 cagctcatta atgccatgtc cattgagagc tgagaggagg agcctcgcat tcctgggaag
2461 agggacctgt ccaagctgtc acactgggag tctcagatgg aaggacaagt gatggggatc
2521 aggccccaga gcttgctgtc ccctgagacc ccatcctggg gagaggggag gactcctctc
2581 cctacgccag ccaagtttcg tcatagccag ttccagctgg gagagacagt gggcgtcgtc
2641 catcctcagt gagaacacca gagaacccgg ggccgggaga aggtggttct tcaagccgag
2701 aggcacgagc tggggacagt tctgcctctg tgactgctgc tttgcatgaa aactcatttg
2761 atgtatattg gggaaataat gagaacttta tttaattttt ttaagaaaaa gggaaaaaaa
2821 cagaaataaa acaaaaagcc gccctgttaa aaaaaataaa aaaaaaaaaa aaaaa
//