LOCUS BC009277 2708 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens G protein-coupled receptor kinase 6, mRNA (cDNA clone
MGC:10490 IMAGE:4053197), complete cds.
ACCESSION BC009277
VERSION BC009277.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2708)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2708)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC009277.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: n Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51896034.
FEATURES Location/Qualifiers
source 1..2708
/db_xref="H-InvDB:HIT000050507"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10490 IMAGE:4053197"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2708
/gene="GRK6"
/db_xref="GeneID:2870"
/db_xref="HGNC:HGNC:4545"
/db_xref="MIM:600869"
CDS 101..1831
/gene="GRK6"
/codon_start=1
/product="G protein-coupled receptor kinase 6"
/protein_id="AAH09277.1"
/db_xref="GeneID:2870"
/db_xref="HGNC:HGNC:4545"
/db_xref="MIM:600869"
/translation="MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEE
LRLSLERDYHSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACG
RQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFAD
YLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLE
KKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIY
HMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAV
HVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKI
KREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKK
LNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVP
IPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCS
DSEEELPTRL"
BASE COUNT 575 a 828 c 818 g 487 t
ORIGIN
1 ccgagccgcg ccgagccgcg ccgatcgcca tccggcctcg gcactcgcgc gcgatcccgg
61 ccggcggcgc ggcccggcgg gccaggcggc gccacagccc atggagctcg agaacatcgt
121 agcgaacacg gtgctactca aggcccggga aggtggcggt ggaaatcgca aaggcaaaag
181 caagaaatgg cggcagatgc tccagttccc tcacatcagc cagtgcgaag agctgcggct
241 cagcctcgag cgtgactatc acagcctgtg cgagcggcag cccattgggc gcctgctgtt
301 ccgagagttc tgtgccacga ggccggagct gagccgctgc gtcgccttcc tggatggggt
361 ggccgagtat gaagtgaccc cggatgacaa gcggaaggca tgtgggcggc agctaacgca
421 gaattttctg agccacacgg gtcctgacct catccctgag gtcccccggc agctggtgac
481 gaactgcacc cagcggctgg agcagggtcc ctgcaaagac cttttccagg aactcacccg
541 gctgacccac gagtacctga gcgtggcccc ttttgccgac tacctcgaca gcatctactt
601 caaccgtttc ctgcagtgga agtggctgga aaggcagcca gtgaccaaaa acaccttcag
661 gcaataccga gtcctgggca aaggtggctt tggggaggtg tgcgcctgcc aggtgcgggc
721 cacaggtaag atgtatgcct gcaagaagct agagaaaaag cggatcaaga agcggaaagg
781 ggaggccatg gcgctgaacg agaagcagat cctggagaaa gtgaacagta ggtttgtagt
841 gagcttggcc tacgcctatg agaccaagga cgcgctgtgc ctggtgctga cactgatgaa
901 cgggggcgac ctcaagttcc acatctacca catgggccag gctggcttcc ccgaagcgcg
961 ggccgtcttc tacgccgccg agatctgctg tggcctggag gacctgcacc gggagcgcat
1021 cgtgtacagg gacctgaagc ccgagaacat cttgctggat gaccacggcc acatccgcat
1081 ctctgacctg ggactagctg tgcatgtgcc cgagggccag accatcaaag ggcgtgtggg
1141 caccgtgggt tacatggctc cggaggtggt gaagaatgaa cggtacacgt tcagccctga
1201 ctggtgggcg ctcggctgcc tcctgtacga gatgatcgca ggccagtcgc ccttccagca
1261 gaggaagaag aagatcaagc gggaggaggt ggagcggctg gtgaaggagg tccccgagga
1321 gtattccgag cgcttttccc cgcaggcccg ctcactttgc tcacagctcc tctgcaagga
1381 ccctgccgaa cgcctggggt gtcgtggggg cagtgcccgc gaggtgaagg agcaccccct
1441 ctttaagaag ctgaacttca agcggctggg agctggcatg ctggagccgc cgttcaagcc
1501 tgacccccag gccatttact gcaaggatgt tctggacatt gaacagttct ctacggtcaa
1561 gggcgtggag ctggagccta ccgaccagga cttctaccag aagtttgcca caggcagtgt
1621 gcccatcccc tggcagaacg agatggtgga gaccgagtgc ttccaagagc tgaatgtctt
1681 tgggctggat ggctcagttc ccccagacct ggactggaag ggccagccac ctgcacctcc
1741 taaaaaggga ctgctgcaga gactcttcag tcgccaagat tgctgtggaa actgcagcga
1801 cagcgaggaa gagctcccca cccgcctcta gcccccagcc cgaggccccc accagcagtt
1861 ggcggtagca gctactccga gcgccgttta cagttttgca cagtgatctt ccccattgtc
1921 cactcaagtc gtggcctggg gaacacagac ggagctgtcc ccagtgtcct ccgtccctca
1981 gcccctggcc tggctgagtt tggcagggcc tgggccatcc ctgggacaaa ggtgcgtccc
2041 ttcagctctt ctccgtggag ctcggggctt tctgtattta tgtatttgta cgaatgtata
2101 tagcgaccag agcattctta attcccgccg cagacctggc gcccccgcct tggctcctgg
2161 gggcagccag ccctggctgg gagagcggga gctggcagag gagccactgc caaactcaag
2221 gctcctctgg cccagcttgg atggctgagg gtggtcacac ccctgagcct tcagcactgt
2281 gctggccacc ccggcctctg agtaagactc gtgcctcccc ctgctgccct gggctcaggc
2341 tgctaccctc tggggcccaa agctgtccct tctcagtgct tgtcagcgct gggtctgggg
2401 cctctgtatg ccctaggcct gtgccaaagt ggccagagat tgggctgcct gtgataccca
2461 tcagcccact gccccggccg gcccagatag gtctgcctct gccttccagc tcccacagcc
2521 tggtccctga tactgggctc tgtcctgcag acacctcttt cagaaacgcc caagcccagc
2581 ccctaggagg gggtggggca tccctggtca accctcaaac attccggact cccctcataa
2641 caatagacac atgtgcccag caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2701 aaaaaaaa
//