LOCUS BC009272 2153 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mesothelin, mRNA (cDNA clone MGC:10273 IMAGE:3957372),
complete cds.
ACCESSION BC009272
VERSION BC009272.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2153)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2153)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC009272.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: j Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 68303642.
FEATURES Location/Qualifiers
source 1..2153
/db_xref="H-InvDB:HIT000034246"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10273 IMAGE:3957372"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2153
/gene="MSLN"
/gene_synonym="CAK1"
/gene_synonym="MPF"
/gene_synonym="SMR"
/db_xref="GeneID:10232"
/db_xref="HGNC:HGNC:7371"
/db_xref="MIM:601051"
CDS 108..1976
/gene="MSLN"
/gene_synonym="CAK1"
/gene_synonym="MPF"
/gene_synonym="SMR"
/codon_start=1
/product="mesothelin"
/protein_id="AAH09272.1"
/db_xref="GeneID:10232"
/db_xref="HGNC:HGNC:7371"
/db_xref="MIM:601051"
/translation="MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQE
AAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLR
CLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQ
RLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQD
QQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSS
RDPSWRQPERTILRPRFRREVEKTACPSGKKAPEIDESLIFYKKWELEACVDAALLAT
QMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSL
ETLKALLEVNKGHEMSPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELS
SVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDL
KALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQ
RQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGTPCLLGPGPVLTVLALLLASTLA"
BASE COUNT 414 a 719 c 654 g 366 t
ORIGIN
1 gccaggctct ccacccccac ttcccaattg aggaaaccga ggcagaggag gctcagagag
61 ctaccggtgg acccacggtg cctccctccc tgggatctac acagaccatg gccttgccaa
121 cggctcgacc cctgttgggg tcctgtggga cccccgccct cggcagcctc ctgttcctgc
181 tcttcagcct cggatgggtg cagccctcga ggaccctggc tggagagaca gggcaggagg
241 ctgcgcccct ggacggagtc ctggccaacc cacctaacat ttccagcctc tcccctcgcc
301 aactccttgg cttcccgtgt gcggaggtgt ccggcctgag cacggagcgt gtccgggagc
361 tggctgtggc cttggcacag aagaatgtca agctctcaac agagcagctg cgctgtctgg
421 ctcaccggct ctctgagccc cccgaggacc tggacgccct cccattggac ctgctgctat
481 tcctcaaccc agatgcgttc tcggggcccc aggcctgcac ccgtttcttc tcccgcatca
541 cgaaggccaa tgtggacctg ctcccgaggg gggctcccga gcgacagcgg ctgctgcctg
601 cggctctggc ctgctggggt gtgcgggggt ctctgctgag cgaggctgat gtgcgggctc
661 tgggaggcct ggcttgcgac ctgcctgggc gctttgtggc cgagtcggcc gaagtgctgc
721 taccccggct ggtgagctgc ccgggacccc tggaccagga ccagcaggag gcagccaggg
781 cggctctgca gggcggggga cccccctacg gccccccgtc gacatggtct gtctccacga
841 tggacgctct gcggggcctg ctgcccgtgc tgggccagcc catcatccgc agcatcccgc
901 agggcatcgt ggccgcgtgg cggcaacgct cctctcggga cccatcctgg cggcagcctg
961 aacggaccat cctccggccg cggttccggc gggaagtgga gaagacagcc tgtccttcag
1021 gcaagaaggc tcccgagata gacgagagcc tcatcttcta caagaagtgg gagctggaag
1081 cctgcgtgga tgcggccctg ctggccaccc agatggaccg cgtgaacgcc atccccttca
1141 cctacgagca gctggacgtc ctaaagcata aactggatga gctctaccca caaggttacc
1201 ccgagtctgt gatccagcac ctgggctacc tcttcctcaa gatgagccct gaggacattc
1261 gcaagtggaa tgtgacgtcc ctggagaccc tgaaggcttt gcttgaagtc aacaaagggc
1321 acgaaatgag tcctcaggtg gccaccctga tcgaccgctt tgtgaaggga aggggccagc
1381 tagacaaaga caccctagac accctgaccg ccttctaccc tgggtacctg tgctccctca
1441 gccccgagga gctgagctcc gtgcccccca gcagcatctg ggcggtcagg ccccaggacc
1501 tggacacgtg tgacccaagg cagctggacg tcctctatcc caaggcccgc cttgctttcc
1561 agaacatgaa cgggtccgaa tacttcgtga agatccagtc cttcctgggt ggggccccca
1621 cggaggattt gaaggcgctc agtcagcaga atgtgagcat ggacttggcc acgttcatga
1681 agctgcggac ggatgcggtg ctgccgttga ctgtggctga ggtgcagaaa cttctgggac
1741 cccacgtgga gggcctgaag gcggaggagc ggcaccgccc ggtgcgggac tggatcctac
1801 ggcagcggca ggacgacctg gacacgctgg ggctggggct acagggcggc atccccaacg
1861 gctacctggt cctagacctc agcatgcaag aggccctctc ggggacgccc tgcctcctag
1921 gacctggacc tgttctcacc gtcctggcac tgctcctagc ctccaccctg gcctgagggc
1981 cccactccct tgctggcccc agccctgctg gggatccccg cctggccagg agcaggcacg
2041 ggtggtcccc gttccacccc aagagaactc gcgctcagta aacgggaaca tgccccctgc
2101 agccaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//