LOCUS BC009271 1901 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens ubiquitin protein ligase E3A, mRNA (cDNA clone
MGC:15720 IMAGE:3353595), complete cds.
ACCESSION BC009271
VERSION BC009271.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1901)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1901)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: p Column: 22.
FEATURES Location/Qualifiers
source 1..1901
/db_xref="H-InvDB:HIT000034245"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15720 IMAGE:3353595"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1901
/gene="UBE3A"
/gene_synonym="ANCR"
/gene_synonym="AS"
/gene_synonym="E6-AP"
/db_xref="GeneID:7337"
/db_xref="HGNC:HGNC:12496"
/db_xref="MIM:601623"
CDS 123..1880
/gene="UBE3A"
/gene_synonym="ANCR"
/gene_synonym="AS"
/gene_synonym="E6-AP"
/codon_start=1
/product="UBE3A protein"
/protein_id="AAH09271.1"
/db_xref="GeneID:7337"
/db_xref="HGNC:HGNC:12496"
/db_xref="MIM:601623"
/translation="MENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNAD
QIRRMMETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNH
NEEDDEEPIPESSELTLQELLGEERRNKKGPRVDPLETELGVKTLDCRKPLIPFEEFI
NEPLNEVLEMDKDYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRIT
VLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVD
EGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIY
NNCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQI
SQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMV
TNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFT
DEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKE
KLKERLLKAITYAKGFGML"
BASE COUNT 644 a 316 c 404 g 537 t
ORIGIN
1 aaaaaattga aactgccttt ctcaatgcac ttgtatattt gtcacctaac gtggaatgtg
61 acttgacgta tcacaatgta tactctcgag atcctaatta tctgaatttg ttcattatcg
121 taatggagaa tagaaatctc cacagtcctg aatatctgga aatggctttg ccattatttt
181 gcaaagcgat gagcaagcta ccccttgcag cccaaggaaa actgatcaga ctgtggtcta
241 aatacaatgc agaccagatt cggagaatga tggagacatt tcagcaactt attacttata
301 aagtcataag caatgaattt aacagtcgaa atctagtgaa tgatgatgat gccattgttg
361 ctgcttcgaa gtgcttgaaa atggtttact atgcaaatgt agtgggaggg gaagtggaca
421 caaatcacaa tgaagaagat gatgaagagc ccatccctga gtccagcgag ctgacacttc
481 aggaactttt gggagaagaa agaagaaaca agaaaggtcc tcgagtggac cccctggaaa
541 ctgaacttgg tgttaaaacc ctggattgtc gaaaaccact tatccctttt gaagagttta
601 ttaatgaacc actgaatgag gttctagaaa tggataaaga ttatactttt ttcaaagtag
661 aaacagagaa caaattctct tttatgacat gtccctttat attgaatgct gtcacaaaga
721 atttgggatt atattatgac aatagaattc gcatgtacag tgaacgaaga atcactgttc
781 tctacagctt agttcaagga cagcagttga atccatattt gagactcaaa gttagacgtg
841 accatatcat agatgatgca cttgtccggc tagagatgat cgctatggaa aatcctgcag
901 acttgaagaa gcagttgtat gtggaatttg aaggagaaca aggagttgat gagggaggtg
961 tttccaaaga attttttcag ctggttgtgg aggaaatctt caatccagat attggtatgt
1021 tcacatacga tgaatctaca aaattgtttt ggtttaatcc atcttctttt gaaactgagg
1081 gtcagtttac tctgattggc atagtactgg gtctggctat ttacaataac tgtatactgg
1141 atgtacattt tcccatggtt gtctacagga agctaatggg gaaaaaagga acttttcgtg
1201 acttgggaga ctctcaccca gttctatatc agagtttaaa agatttattg gagtatgaag
1261 ggaatgtgga agatgacatg atgatcactt tccagatatc acagacagat ctttttggta
1321 acccaatgat gtatgatcta aaggaaaatg gtgataaaat tccaattaca aatgaaaaca
1381 ggaaggaatt tgtcaatctt tattctgact acattctcaa taaatcagta gaaaaacagt
1441 tcaaggcttt tcggagaggt tttcatatgg tgaccaatga atctccctta aagtacttat
1501 tcagaccaga agaaattgaa ttgcttatat gtggaagccg gaatctagat ttccaagcac
1561 tagaagaaac tacagaatat gacggtggct ataccaggga ctctgttctg attagggagt
1621 tctgggaaat cgttcattca tttacagatg aacagaaaag actcttcttg cagtttacaa
1681 cgggcacaga cagagcacct gtgggaggac taggaaaatt aaagatgatt atagccaaaa
1741 atggcccaga cacagaaagg ttacctacat ctcatacttg ctttaatgtg cttttacttc
1801 cggaatactc aagcaaagaa aaacttaaag agagattgtt gaaggccatc acgtatgcca
1861 aaggatttgg catgctgtaa aacaaaaaaa aaaaaaaaaa a
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