LOCUS BC008933 1758 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens branched chain keto acid dehydrogenase E1, alpha
polypeptide, mRNA (cDNA clone MGC:2355 IMAGE:2822372), complete
cds.
ACCESSION BC008933
VERSION BC008933.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1758)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1758)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC008933.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: f Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38372929.
FEATURES Location/Qualifiers
source 1..1758
/db_xref="H-InvDB:HIT000034087"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2355 IMAGE:2822372"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1758
/gene="BCKDHA"
/gene_synonym="MSU"
/gene_synonym="MSUD1"
/db_xref="GeneID:593"
/db_xref="HGNC:HGNC:986"
/db_xref="MIM:608348"
CDS 2..1339
/gene="BCKDHA"
/gene_synonym="MSU"
/gene_synonym="MSUD1"
/codon_start=1
/product="branched chain keto acid dehydrogenase E1, alpha
polypeptide"
/protein_id="AAH08933.1"
/db_xref="GeneID:593"
/db_xref="HGNC:HGNC:986"
/db_xref="MIM:608348"
/translation="MAVAIAAARVWRLNRGLSQAALLLLRQPGARGLARSHPPRQQQQ
FSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKV
LKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYRE
AGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVG
AAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTS
EQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIG
HHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVME
AFEQAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYPLDHFDK"
BASE COUNT 387 a 547 c 506 g 318 t
ORIGIN
1 gatggcggta gcgatcgctg cagcgagggt ctggcggcta aaccgtggtt tgagccaggc
61 tgccctcctg ctgctgcggc agcctggggc tcggggactg gctagatctc acccccccag
121 gcagcagcag cagttttcat ctctggatga caagccccag ttcccagggg cctcggcgga
181 gtttatagat aagttggaat tcatccagcc caacgtcatc tctggaatcc ccatctaccg
241 cgtcatggac cggcaaggcc agatcatcaa ccccagcgag gacccccacc tgccgaagga
301 gaaggtgctg aagctctaca agagcatgac actgcttaac accatggacc gcatcctcta
361 tgagtctcag cggcagggcc ggatctcctt ctacatgacc aactatggtg aggagggcac
421 gcacgtgggg agtgccgccg ccctggacaa cacggacctg gtgtttggcc agtaccggga
481 ggcaggtgtg ctgatgtatc gggactaccc cctggaacta ttcatggccc agtgctatgg
541 caacatcagt gacttgggca aggggcgcca gatgcctgtc cactacggct gcaaggaacg
601 ccacttcgtc actatctcct ctccactggc cacgcagatc cctcaggcgg tgggggcggc
661 gtacgcagcc aagcgggcca atgccaacag ggtcgtcatc tgttacttcg gcgagggggc
721 agccagtgag ggggacgccc atgccggctt caacttcgct gccacacttg agtgccccat
781 catcttcttc tgccggaaca atggctacgc catctccacg cccacctctg agcagtatcg
841 cggcgatggc attgcagcac gaggccccgg gtatggcatc atgtcaatcc gcgtggatgg
901 taatgatgtg tttgccgtat acaacgccac aaaggaggcc cgacggcggg ctgtggcaga
961 gaaccagccc tttctcatcg aggccatgac ctacaggatc gggcaccaca gcaccagtga
1021 cgacagttca gcgtaccgct cggtggatga ggtcaattac tgggataaac aggaccaccc
1081 catctcccgg ctgcggcact atctgctgag ccaaggctgg tgggatgagg agcaggagaa
1141 ggcctggagg aagcagtccc gcaggaaggt gatggaggcc tttgagcagg ccgagcggaa
1201 gcccaaaccc aaccccaacc tgctcttctc agacgtgtat caggagatgc ccgcccagct
1261 ccgcaagcag caggagtctc tggcccgcca cctgcagacc tacggggagc actacccact
1321 ggatcacttc gataagtgag acctgctcag cccaccccca cccatcctca gctaccccga
1381 gaggtagccc cactctaagg ggagcagggg gacctgacag cacaccactg tcttccccag
1441 tcagctccct ctaaaatact cagcggccag ggcggctgcc actcttcacc cctgctcctc
1501 ccggctgtta cattgtcagg ggacagcatc tgcagcagtt gctgaggctc cgtcagcccc
1561 ctcttcacct gttgttacag tgccttctcc caggggctgg gtgagggcac attcaggact
1621 agaagcccct ctgggcatgg ggtggacatg gcaggtcagc ctgtggaact tgcgcaggtg
1681 cgagtggcca gcagaggtca cgaataaact gcatctctgc gcctggctct ctaaaaaaaa
1741 aaaaaaaaaa aaaaaaaa
//