LOCUS BC008876 2676 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens endothelin 3, mRNA (cDNA clone MGC:15067
IMAGE:4139312), complete cds.
ACCESSION BC008876
VERSION BC008876.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2676)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2676)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC008876.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: m Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46370058.
FEATURES Location/Qualifiers
source 1..2676
/db_xref="H-InvDB:HIT000034043"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15067 IMAGE:4139312"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2676
/gene="EDN3"
/gene_synonym="ET3"
/gene_synonym="MGC15067"
/gene_synonym="MGC61498"
/db_xref="GeneID:1908"
/db_xref="HGNC:HGNC:3178"
/db_xref="MIM:131242"
CDS 387..1103
/gene="EDN3"
/gene_synonym="ET3"
/gene_synonym="MGC15067"
/gene_synonym="MGC61498"
/codon_start=1
/product="endothelin 3"
/protein_id="AAH08876.1"
/db_xref="GeneID:1908"
/db_xref="HGNC:HGNC:3178"
/db_xref="MIM:131242"
/translation="MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEG
DCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTY
KDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCA
CVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPG
SGLALAPSTCPRCLFQEGAP"
BASE COUNT 702 a 677 c 702 g 595 t
ORIGIN
1 cgctgtcctg ggtgcgcctc gggccgctgc gctcctggcc agctcccccc agcgcctggg
61 aggcgacccc cagtgcgccc gggttcaaag gcccggcgag gcagttccag cccctctggg
121 gggcggggag gcgacggggg tggtgcagaa gccagaaaag cccgagccac agccggccag
181 ctccgcgcag ggatgggcag cgcgctctga aagtttatga ccgccgcagc caactcctgg
241 ccggagctgg agacgcagcg agcgatcggc cggcctcgaa cccccacagc tggagggcga
301 ggccagctgt acccggcccc agtgcccttt cgcggccaca agcggccgtc ctcctggtcc
361 ggtgctccgg cgcctgatct aggttcatgg agccggggct gtggctcctt ttcgggctca
421 cagtgacctc cgccgcagga ttcgtgcctt gctcccagtc tggggatgct ggcaggcgcg
481 gcgtgtccca ggcccccact gcagccagat ctgaggggga ctgtgaagag actgtggctg
541 gccctggcga ggagactgtg gctggccctg gcgaggggac tgtggccccg acagcactgc
601 agggtccaag ccctggaagc cctgggcagg agcaggcggc cgagggggcc cctgagcacc
661 accgatccag gcgctgcacg tgcttcacct acaaggacaa ggagtgtgtc tactattgcc
721 acctggacat catttggatc aacactcccg aacagacggt gccctatgga ctgtccaact
781 acagaggaag cttccggggc aagaggtctg cggggccact tccagggaat ctgcagctct
841 cacatcggcc acacttgcgc tgcgcttgtg tggggagata tgacaaggcc tgcctgcact
901 tttgcaccca aactctggac gtcagcagta attcaaggac ggcagaaaaa acagacaaag
961 aagaggaagg gaaggttgaa gtcaaggacc aacaaagcaa gcaggcttta gacctccacc
1021 atccaaagct catgcccggc agtggactcg ccctcgctcc atctacctgc ccccgctgcc
1081 tctttcagga aggagcccct taggaggaca ggcctgcagc atcctggtct cgggaggctt
1141 ctgtcattgc tcacacacag ttcagatttc cacctcttta tagacaagaa gtgaatttgc
1201 ctggggcaga acacccaccc aaagagtccc cacttaacaa tacccccccc ccacggcaag
1261 aatgcccaaa tccgaatgac cccagttttc ctaatgagta aaatgatccc agatgtgccc
1321 cagagcatga cgcctgcagc tccggtttca tgcaggaaat tggttttgga gagttttggc
1381 aagttggaaa gccacttact ggcttttgac atgacttctc ttggagaata agtggactcc
1441 aagctaactc tttgcaaatg taaacacatg tccatcttgt aataaatgca aaatgcccgt
1501 gcagcagaag catgcgactt tcatatcctt gcctagaata ggctgcatgg tgtatgtcag
1561 tgagggccac gaggcgtcgg ctttagacac agatcatagc tctacaggag tttatgaatt
1621 tgaagcttat gggattttgg cagagaaatt ttcagctgtg cttgataccc accaaaagaa
1681 tgtatctcga aagaatgaag gaagaagaaa aaaggatcct tgatgtttgt gacaagaaaa
1741 tgagaaagtt agtatctgca atacagagct tgttcctgtt cagtgactga ccctctgtat
1801 tctgtataga caccaggccg atacacagtg gagttcccag gccttgtttg caggaagccg
1861 actgtaaaga cagccccagc tcaaggctat taggttgaat atttgctttc atgagtaaat
1921 gtggatcttt ggggaatggc ttcaaaataa gtcacgaaca caaattcttt gtaaattatg
1981 taaattcctg tttatataaa ttggcaacaa cttataccgt ctgacagttc aaaatctctt
2041 tcagctgcgc tcttcccacc gagccgagct tactgtgagt gtggagatgt tatcccacca
2101 tgtaaagtcg cctgcgcagg ggagggctgc ccatctcccc aacccagtca cagagagata
2161 ggaaacggca tttgagtggg tgtccagggc cccgtagaga gacatttaag atggtgtatg
2221 acagagcatt ggccttgacc aaatgttaaa tcctctgtgt gtatttcata agttattaca
2281 ggtataaaag tgatgaccta tcatgaggaa atgaaagtgg ctgatttgct ggtaggattt
2341 tgtacagttt agagaagcga ttatttattg tgaaactgtt ctccactcca actcctttat
2401 gtggatctgt tcaaagtagt cactgtatat acgtatagag aggtagatag gtaggtagat
2461 tttaaattgc attctgaata caaactcata ctccttagag cttgaattac atttttaaaa
2521 tgcatatgtg ctgtttggca ccgtggcaag atggtatcag agagaaaccc atcaattgct
2581 caaatactca gaaagtactg tcaaaagcct aataaaaaac ctaaagtttg ctctgaaaaa
2641 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
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