LOCUS BC008856 2488 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens deltex homolog 2 (Drosophila), mRNA (cDNA clone
MGC:14983 IMAGE:4107018), complete cds.
ACCESSION BC008856
VERSION BC008856.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2488)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2488)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC008856.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: a Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24308252.
FEATURES Location/Qualifiers
source 1..2488
/db_xref="H-InvDB:HIT000034026"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14983 IMAGE:4107018"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2488
/gene="DTX2"
/gene_synonym="KIAA1528"
/gene_synonym="RNF58"
/db_xref="GeneID:113878"
CDS 192..2060
/gene="DTX2"
/gene_synonym="KIAA1528"
/gene_synonym="RNF58"
/codon_start=1
/product="DTX2 protein"
/protein_id="AAH08856.1"
/db_xref="GeneID:113878"
/translation="MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQ
QFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQ
HSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHT
QTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHTGVACSCHQCLSGSRTGPVSGRYRHSM
TNLPAYPVPQHPPHRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGS
QPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQMPKPSRVQQA
LAGMTSVLMSAIGLPVCLSRAPQPTSPPASRLASKSHGSVKRLRKMSVKEATPKPEPE
PEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFH
LLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILI
VYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGT
SSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ"
misc_feature 510..734
/gene="DTX2"
/gene_synonym="KIAA1528"
/gene_synonym="RNF58"
/note="WWE; Region: Domain in Deltex and TRIP12
homologues. Possibly involved in regulation of
ubiquitin-mediated proteolysis"
/db_xref="CDD:smart00678"
BASE COUNT 506 a 848 c 710 g 424 t
ORIGIN
1 gagagtcgga gccacagcca gagccctgcc caggccgagc cggagctgca gcccgagcgc
61 ggtggtgccc tcagccccgt cctcttgtcc tcctcagcct cgatctgccg gaggcgctgg
121 gcaatgaccc cgggactcca ggccagaggg gtctgaagct gtttgggaaa gcagcgggac
181 tccttgggaa gatggccatg gccccaagcc cttccctggt gcaggtgtac accagccccg
241 cggctgtggc cgtgtgggaa tggcaggacg ggctgggcac ctggcacccc tacagtgcca
301 ccgtctgcag cttcatcgag cagcagtttg tccagcagaa gggccaacgt tttgggcttg
361 ggagcctggc ccacagcatc cccttgggcc aggcagaccc ctcgctggcc ccttacatta
421 ttgacctccc cagctggacc cagttccgcc aggacaccgg caccatgcgg gctgtgcgga
481 gacacctgtt cccccagcac tcagcccctg gccgaggtgt cgtctgggag tggctgagcg
541 acgatggctc ctggactgcc tatgaagcca gcgtctgtga ctatctggag cagcaggtgg
601 ccaggggcaa ccagctcgtg gacttggcgc ccctggggta caactacact gtcaactaca
661 ccacccacac gcagaccaac aagacttcca gcttttgccg cagcgtgcgg cgccaagcag
721 ggccgcctta cccggtgacc accatcatcg ctccgccggg ccacacaggc gtcgcctgct
781 cttgccacca gtgcctcagt ggcagcagaa ctggccccgt gtcaggccgc taccgccact
841 ccatgaccaa cctccctgca taccccgtcc cccagcaccc cccacacagg accgcttctg
901 tgtttgggac ccaccaggcc tttgcaccgt acaacaaacc ctcactctcc ggggcccggt
961 ctgcgcccag gctgaacacc accaacgcct ggggcgcagc tcctccttcc ctggggagcc
1021 agcccctcta ccgctccagc ctctcccacc tgggaccgca gcacctgccc ccaggatcct
1081 ccacctccgg tgcagtcagt gcctccctcc ccagcggtcc ctcaagcagc ccagggagcg
1141 tccctgccac tgtgcccatg cagatgccaa agcccagcag agtccagcag gcgctcgcag
1201 gcatgacgag tgttctgatg tcagccattg gactccctgt gtgtcttagc cgcgcacccc
1261 agcccaccag ccctcccgcc tcccgtctgg cttccaaaag tcacggctca gttaagagat
1321 tgaggaaaat gtccgtgaaa gaagcgaccc cgaagccaga gccagagcca gagcaggtca
1381 taaaaaacta cacggaagag ctgaaagtgc ccccagatga ggactgcatc atctgcatgg
1441 agaagctgtc cacagcgtct ggatacagcg atgtgactga cagcaaggca atcgggtccc
1501 tagctgtggg ccacctcacc aagtgcagcc atgccttcca cctgctgtgc ctcctggcca
1561 tgtactgcaa cggcaataag gatggaagtc tgcagtgtcc ctcctgcaaa accatctatg
1621 gagagaagac ggggacccag ccccagggaa agatggaggt attacggttc cagatgtcgc
1681 tccccggcca cgaggactgc gggaccatcc tcatagttta cagcattccc catggtatcc
1741 agggccctga gcaccccaat cccggaaagc cgttcactgc cagagggttt ccccgccagt
1801 gctaccttcc agacaacgcc cagggccgca aggtcctaga gctcctgaag gtggcctgga
1861 agaggcggct catcttcaca gtgggcacgt ccagcaccac gggtgagacg gacaccgtgg
1921 tatggaacga gatccaccac aagacagaga tggaccgcaa cattacgggc cacggctatc
1981 ccgaccccaa ctacctgcag aacgtgctgg ctgagctggc tgcccagggg gtgaccgagg
2041 actgcctgga gcagcagtga cctcgcaccc cagcacgccc gcctctggtg gccaccccgc
2101 tgccccatgg ctggctgggt ggccaggcag gaagtgccca gcccgagagg ctgggaggtt
2161 tgttgagggt gtggggtgtg ccccacctga agccggggct ccccctgcct gcctctctct
2221 cctcctcccc tctgggaatt gggcagccct gggcagttgt actcatgggg gcttaggatg
2281 cagctacctc agtgcgcagg gcccgtctgt cctctggggg ctgcttcggg cccgcggtgc
2341 tcggggcctg gtgtggggcg agtagagact tccccagcct ggacgggcgt gggttctggg
2401 tcagcttctt ttacctcaat tttgtttgca ataaatgctc tatagccaaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//