LOCUS BC008786 4243 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha
polypeptide), mRNA (cDNA clone MGC:3697 IMAGE:3629647), complete
cds.
ACCESSION BC008786
VERSION BC008786.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4243)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4243)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC008786.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: i Column: 12.
FEATURES Location/Qualifiers
source 1..4243
/db_xref="H-InvDB:HIT000033967"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3697 IMAGE:3629647"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4243
/gene="ITGA5"
/gene_synonym="CD49e"
/gene_synonym="VLA5A"
/db_xref="GeneID:3678"
/db_xref="HGNC:HGNC:6141"
/db_xref="MIM:135620"
CDS 54..3203
/gene="ITGA5"
/gene_synonym="CD49e"
/gene_synonym="VLA5A"
/codon_start=1
/product="integrin, alpha 5 (fibronectin receptor, alpha
polypeptide)"
/protein_id="AAH08786.1"
/db_xref="GeneID:3678"
/db_xref="HGNC:HGNC:6141"
/db_xref="MIM:135620"
/translation="MGSRTPESPLHAVQLRWGPRRRPPLLPLLLLLLPPPPRVGGFNL
DAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPWG
ASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAHGSSILACAPLY
SWRTEKEPLSDPVGTCYLSTDNFTRILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGR
VVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSV
AVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATD
VNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLTLTGHDEFGRF
GSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQVLQPLWAAS
HTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIFPAMFNP
EERSCSLEGNPVACINLSFCLNASGKHVADSIGFTVELQLDWQKQKGGVRRALFLASR
QATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPQAPVDSHGLR
PALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLGDKNALNLTFHAQN
VGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAG
ASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVS
KPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQ
QLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHHQQKREAPSRSSASSGPQILKCPEA
ECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQCEAVYKALKMPYRILP
RQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSL
PYGTAMEKAQLKPPATSDA"
BASE COUNT 933 a 1289 c 1166 g 855 t
ORIGIN
1 gtttaggaag cggctccggg tcggtggccc caggacaggg aagagcgggc gctatgggga
61 gccggacgcc agagtcccct ctccacgccg tgcagctgcg ctggggcccc cggcgccgac
121 ccccgctgct gccgctgctg ttgctgctgc tgccgccgcc acccagggtc gggggcttca
181 acttagacgc ggaggcccca gcagtactct cggggccccc gggctccttc ttcggattct
241 cagtggagtt ttaccggccg ggaacagacg gggtcagtgt gctggtggga gcacccaagg
301 ctaataccag ccagccagga gtgctgcagg gtggtgctgt ctacctctgt ccttggggtg
361 ccagccccac acagtgcacc cccattgaat ttgacagcaa aggctctcgg ctcctggagt
421 cctcactgtc cagctcagag ggagaggagc ctgtggagta caagtccttg cagtggttcg
481 gggcaacagt tcgagcccat ggctcctcca tcttggcatg cgctccactg tacagctggc
541 gcacagagaa ggagccactg agcgaccccg tgggcacctg ctacctctcc acagataact
601 tcacccgaat tctggagtat gcaccctgcc gctcagattt cagctgggca gcaggacagg
661 gttactgcca aggaggcttc agtgccgagt tcaccaagac tggccgtgtg gttttaggtg
721 gaccaggaag ctatttctgg caaggccaga tcctgtctgc cactcaggag cagattgcag
781 aatcttatta ccccgagtac ctgatcaacc tggttcaggg gcagctgcag actcgccagg
841 ccagttccat ctatgatgac agctacctag gatactctgt ggctgttggt gaattcagtg
901 gtgatgacac agaagacttt gttgctggtg tgcccaaagg gaacctcact tacggctatg
961 tcaccatcct taatggctca gacattcgat ccctctacaa cttctcaggg gaacagatgg
1021 cctcctactt tggctatgca gtggccgcca cagacgtcaa tggggacggg ctggatgact
1081 tgctggtggg ggcacccctg ctcatggatc ggacccctga cgggcggcct caggaggtgg
1141 gcagggtcta cgtctacctg cagcacccag ccggcataga gcccacgccc acccttaccc
1201 tcactggcca tgatgagttt ggccgatttg gcagctcctt gacccccctg ggggacctgg
1261 accaggatgg ctacaatgat gtggccatcg gggctccctt tggtggggag acccagcagg
1321 gagtagtgtt tgtatttcct gggggcccag gagggctggg ctctaagcct tcccaggttc
1381 tgcagcccct gtgggcagcc agccacaccc cagacttctt tggctctgcc cttcgaggag
1441 gccgagacct ggatggcaat ggatatcctg atctgattgt ggggtccttt ggtgtggaca
1501 aggctgtggt atacaggggc cgccccatcg tgtccgctag tgcctccctc accatcttcc
1561 ccgccatgtt caacccagag gagcggagct gcagcttaga ggggaaccct gtggcctgca
1621 tcaaccttag cttctgcctc aatgcttctg gaaaacacgt tgctgactcc attggtttca
1681 cagtggaact tcagctggac tggcagaagc agaagggagg ggtacggcgg gcactgttcc
1741 tggcctccag gcaggcaacc ctgacccaga ccctgctcat ccagaatggg gctcgagagg
1801 attgcagaga gatgaagatc tacctcagga acgagtcaga atttcgagac aaactctcgc
1861 cgattcacat cgctctcaac ttctccttgg acccccaagc cccagtggac agccacggcc
1921 tcaggccagc cctacattat cagagcaaga gccggataga ggacaaggct cagatcttgc
1981 tggactgtgg agaagacaac atctgtgtgc ctgacctgca gctggaagtg tttggggagc
2041 agaaccatgt gtacctgggt gacaagaatg ccctgaacct cactttccat gcccagaatg
2101 tgggtgaggg tggcgcctat gaggctgagc ttcgggtcac cgcccctcca gaggctgagt
2161 actcaggact cgtcagacac ccagggaact tctccagcct gagctgtgac tactttgccg
2221 tgaaccagag ccgcctgctg gtgtgtgacc tgggcaaccc catgaaggca ggagccagtc
2281 tgtggggtgg ccttcggttt acagtccctc atctccggga cactaagaaa accatccagt
2341 ttgacttcca gatcctcagc aagaatctca acaactcgca aagcgacgtg gtttcctttc
2401 ggctctccgt ggaggctcag gcccaggtca ccctgaacgg tgtctccaag cctgaggcag
2461 tgctattccc agtaagcgac tggcatcccc gagaccagcc tcagaaggag gaggacctgg
2521 gacctgctgt ccaccatgtc tatgagctca tcaaccaagg ccccagctcc attagccagg
2581 gtgtgctgga actcagctgt ccccaggctc tggaaggtca gcagctccta tatgtgacca
2641 gagttacggg actcaactgc accaccaatc accccattaa cccaaagggc ctggagttgg
2701 atcccgaggg ttccctgcac caccagcaaa aacgggaagc tccaagccgc agctctgctt
2761 cctcgggacc tcagatcctg aaatgcccgg aggctgagtg tttcaggctg cgctgtgagc
2821 tcgggcccct gcaccaacaa gagagccaaa gtctgcagtt gcatttccga gtctgggcca
2881 agactttctt gcagcgggag caccagccat ttagcctgca gtgtgaggct gtgtacaaag
2941 ccctgaagat gccctaccga atcctgcctc ggcagctgcc ccaaaaagag cgtcaggtgg
3001 ccacagctgt gcaatggacc aaggcagaag gcagctatgg cgtcccactg tggatcatca
3061 tcctagccat cctgtttggc ctcctgctcc taggtctact catctacatc ctctacaagc
3121 ttggattctt caaacgctcc ctcccatatg gcaccgccat ggaaaaagct cagctcaagc
3181 ctccagccac ctctgatgcc tgagtcctcc caatttcaga ctcccattcc tgaagaacca
3241 gtccccccac cctcattcta ctgaaaagga ggggtctggg tacttcttga aggtgctgac
3301 ggccagggag aagctcctct ccccagccca gagacatact tgaagggcca gagccagggg
3361 ggtgaggagc tggggatccc tcccccccat gcactgtgaa ggacccttgt ttacacatac
3421 cctcttcatg gatgggggaa ctcagatcca gggacagagg ccccagcctc cctgaagcct
3481 ttgcattttg gagagtttcc tgaaacaact tggaaagata actaggaaat ccattcacag
3541 ttctttgggc cagacatgcc acaaggactt cctgtccagc tccaacctgc aaagatctgt
3601 cctcagcctt gccagagatc caaaagaagc ccccagctaa gaacctggaa cttggggagt
3661 taagacctgg cagctctgga cagccccacc ctggtgggcc aacaaagaac actaactatg
3721 catggtgccc caggaccagc tcaggacaga tgccacacaa ggatagatgc tggcccaggg
3781 cccagagccc agctccaagg ggaatcagaa ctcaaatggg gccagatcca gcctggggtc
3841 tggagttgat ctggaaccca gactcagaca ttggcaccta atccaggcag atccaggact
3901 atatttgggc ctgctccaga cctgatcctg gaggcccagt tcaccctgat ttaggagaag
3961 ccaggaattt cccaggaccc tgaaggggcc atgatggcaa cagatctgga acctcagcct
4021 ggccagacac aggccctccc tgttccccag agaaagggga gcccactgtc ctgggcctgc
4081 agaatttggg ttctgcctgc cagctgcact gatgctgccc ctcatctctc tgcccaaccc
4141 ttccctcacc ttggcaccag acacccagga cttatttaaa ctctgttgca agtgcaataa
4201 atctgaccca gtgcccccac tgaccaaaaa aaaaaaaaaa aaa
//