LOCUS BC008776 3532 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens gem (nuclear organelle) associated protein 5, mRNA
(cDNA clone IMAGE:3143002), partial cds.
ACCESSION BC008776
VERSION BC008776.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3532)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3532)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 28, 2003 this sequence version replaced BC008776.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: f Column: 12.
FEATURES Location/Qualifiers
source 1..3532
/db_xref="H-InvDB:HIT000087154"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3143002"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..3532
/gene="GEMIN5"
/gene_synonym="DKFZP586M1824"
/db_xref="GeneID:25929"
/db_xref="MIM:607005"
CDS <1..2768
/gene="GEMIN5"
/gene_synonym="DKFZP586M1824"
/codon_start=3
/product="GEMIN5 protein"
/protein_id="AAH08776.2"
/db_xref="GeneID:25929"
/db_xref="MIM:607005"
/translation="HEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEP
YRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHQGRLLCVA
WSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKP
TLRTPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVI
CTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLIKKRKARSLLPLSTSLDHRSKEEL
HQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLENGHPEL
FHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQDQYV
KAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPVLKDLYLSWGTVLERDG
HYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGEDELSASLALRCAQEL
LLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGKSSSSYHTWNTGTE
GPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQLLLHICHDLTLA
VLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRDKLGDHQSPA
TPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDTASTEETD
PETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQETLAEMI
RQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTEANQ
RMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYRR
HCQTFCM"
misc_feature 36..401
/gene="GEMIN5"
/gene_synonym="DKFZP586M1824"
/note="WD40; Region: WD40 domain, found in a number of
eukaryotic proteins that cover a wide variety of functions
including adaptor/regulatory modules in signal
transduction, pre-mRNA processing and cytoskeleton
assembly"
/db_xref="CDD:cd00200"
BASE COUNT 1014 a 825 c 837 g 856 t
ORIGIN
1 atcatgagca tggcagccag ccagaattga gctatctgat ggcctctggc tccaacaatg
61 cagtcattta cgtgcacaac ctgaagactg tcatagagag cagccctgag tctccagtga
121 ccattacaga gccctaccgg accctctcag ggcatacggc caagattacc agtgtggcgt
181 ggagcccaca tcatgatgga aggctggtat ctgcttccta tgatggtaca gcccaggtgt
241 gggatgctct ccgggaagag cccctgtgca atttccgagg acatcaaggt cgactgcttt
301 gtgtggcatg gtctcctttg gatccagact gcatctattc aggggcagat gacttttgtg
361 tgcacaagtg gctcacttcc atgcaagatc attcccggcc tcctcaaggc aaaaaaagta
421 ttgaattgga gaaaaaacgg ctctctcaac ctaaggcaaa gcccaaaaag aagaaaaagc
481 ccaccttgag aactcctgta aagctggaat cgattgatgg aaatgaagaa gaaagcatga
541 aggagaactc aggacctgtt gagaatggtg tgtcagacca agaaggggag gagcaagcac
601 gggagccgga attaccctgt ggccttgctc cagcggtttc tagagaacca gttatctgca
661 ctccagtttc ctcaggcttt gaaaagtcaa aagtcaccat taataacaaa gtcattttac
721 tgaaaaagga gccaccaaaa gagaagccag aaaccttaat caagaagaga aaagctcgtt
781 ccttgcttcc cctgagtaca agcctggacc acagatccaa agaggagctt catcaggact
841 gtttggtact agcaactgca aagcactcca gagagctgaa tgaagatgtg tctgctgatg
901 ttgaggaaag atttcatctg gggcttttca cagacagggc taccctgtat agaatgattg
961 atattgaagg aaaaggtcac ttagaaaatg gccaccctga gttatttcac cagcttatgc
1021 tttggaaagg agatctcaaa ggtgttctcc agactgcagc agaaagaggg gagctgacag
1081 acaaccttgt ggctatggca ccagcagctg gctaccatgt gtggctatgg gctgtggaag
1141 cttttgccaa acagctgtgt tttcaggatc agtatgtcaa ggctgcttct cacctacttt
1201 ccatccacaa agtgtatgaa gcggtggagc tgctcaagtc aaaccatttt tacagggaag
1261 ctattgcgat tgccaaggcc cggctgcgcc cggaggaccc agtcctgaag gacttgtacc
1321 tcagctgggg aaccgtccta gaaagagatg gccactatgc tgtagctgcc aaatgctatt
1381 taggggccac ttgtgcttat gatgcagcca aagttttggc caaaaagggg gatgcggcat
1441 cacttagaac ggctgcagag ttggctgcca tcgtaggaga ggatgagttg tctgcttccc
1501 tggctctcag atgtgcccaa gagctgcttc tggccaacaa ctgggtggga gcccaggaag
1561 ccctgcagct gcatgaaagt ctacagggtc agagattggt gttttgcctt ctggagctac
1621 tgtccaggca tctggaggaa aagcagcttt cagagggcaa aagctcctcc tcttaccaca
1681 cttggaacac gggcaccgaa gggcctttcg tggagagggt gactgcagtg tggaagagca
1741 tcttcagcct tgacacccct gagcagtatc aggaagcctt tcagaagctg cagaacatca
1801 agtacccatc tgctacaaat aacacacctg ccaaacagct cctgcttcac atttgccatg
1861 acttgaccct ggcagtgctg agccaacaga tggcctcctg ggacgaggct gtgcaggcgc
1921 tccttcgggc ggtggtccgg agctatgact cagggagctt caccatcatg caggaagtgt
1981 actcagcctt tctccctgat ggctgtgacc acctaagaga caagttgggg gaccatcaat
2041 cccctgccac accagctttc aaaagtttgg aggccttttt tctttatggg cgtctgtatg
2101 aattctggtg gtctctctcc agaccttgcc caaattccag tgtctgggta agggctggtc
2161 acagaacact ctctgttgag ccaagccagc agttagacac tgccagcact gaagaaacgg
2221 accctgaaac ttctcagcca gagccaaaca ggccttcaga actagacttg agactcacag
2281 aagaaggtga gcgaatgctg agtactttta aggagctctt ttcagaaaag catgccagtc
2341 tccaaaactc acagagaact gttgctgaag tccaagagac cttggcagaa atgatccgac
2401 aacaccaaaa gagtcaactc tgtaaatcca cagcaaatgg tcctgataag aatgaaccgg
2461 aagtagaagc agagcagccc ctctgcagtt ctcagagcca gtgtaaagaa gaaaaaaatg
2521 agccactttc tctgcctgag ttaaccaaaa ggcttaccga ggcaaatcag agaatggcaa
2581 aatttcctga gagcattaag gcctggccct tcccagatgt gctggagtgc tgcctcgtcc
2641 tgcttctcat caggtcccac tttcctggct gtctggccca ggaaatgcag cagcaggccc
2701 aagagctcct tcagaaatac ggcaacacga aaacttacag aagacactgc cagaccttct
2761 gtatgtgaat tttcacacac cttgaagaaa ctgccaaatt gaaaatgttt gacatctttc
2821 acctctgcag ttatgcctca ccagacattc actctggtcc ctagatgttt ttgcagtaat
2881 ccaaaagaat acaaacaagg attaagtttg aatcaaccct gcctacccat agacaacggt
2941 ggatctgact ttagactcaa ttgtggtctc ctactggagg gaagatcatg aaaagcccac
3001 agtagttatt cagaactaac acctgcagag tgttggtcat ctctacagcc ttaggcaggt
3061 ttcacccaaa gaggagaaac ttctgtcgtc acccaaagtg ttacatgctt aaaacacaag
3121 ctacctttgt aaatacttca tctgatcaga agtgtgtcat gcttgtttga gatggagttg
3181 ctgcatttta ggactattga tacctttttt taattgtttt tataatattt aatttgaaag
3241 aggagaccct tctctctcta ctctttcata gactgaagtt tgaatatgaa ataggcctta
3301 accatcatgt tgactctcct gtcagaattt taggttggaa atttggtttt attctttcat
3361 gtaattgctt atttgaacag atcacttact aaagctttag aagaagtgat tcaaatgtgt
3421 gttttccctt cagttttata acaaatggat tgatggcagt caaatagctc aggaataaat
3481 tactgtttca atggtaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//