LOCUS BC008457 1574 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens major histocompatibility complex, class I, C, mRNA
(cDNA clone MGC:14707 IMAGE:4249847), complete cds.
ACCESSION BC008457
VERSION BC008457.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1574)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1574)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 21 Row: e Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1574
/db_xref="H-InvDB:HIT000033806"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14707 IMAGE:4249847"
/tissue_type="Prostate"
/clone_lib="NIH_MGC_83"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1574
/gene="HLA-C"
/gene_synonym="D6S204"
/gene_synonym="HLA-JY3"
/db_xref="GeneID:3107"
/db_xref="MIM:142840"
CDS 11..1129
/gene="HLA-C"
/gene_synonym="D6S204"
/gene_synonym="HLA-JY3"
/codon_start=1
/product="HLA-C protein"
/protein_id="AAH08457.1"
/db_xref="GeneID:3107"
/db_xref="MIM:142840"
/translation="MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTAVSRPGRGEP
HFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSL
RNLRGYYNQSEARSHIIQRMYGCDVGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAA
DTAAQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLKNGKETLQRAEHPKTHVTHHPV
SDHEATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG
EEQRYTCHVQHEGLPEPLTLRWEPSSQPTIPIVGIVAGLAVLAVLAVLGAVVAVVMCR
RKSSGHFLPTGGKGGSCSQAASSNSAQGSDESLIACKA"
misc_feature 83..619
/gene="HLA-C"
/gene_synonym="D6S204"
/gene_synonym="HLA-JY3"
/note="MHC_I; Region: Class I Histocompatibility antigen,
domains alpha 1 and 2"
/db_xref="CDD:pfam00129"
misc_feature 674..889
/gene="HLA-C"
/gene_synonym="D6S204"
/gene_synonym="HLA-JY3"
/note="IGc1; Region: Immunoglobulin C-Type"
/db_xref="CDD:smart00407"
BASE COUNT 349 a 443 c 475 g 307 t
ORIGIN
1 agacgccgag atgcgggtca tggcgccccg aaccctcatc ctgctgctct cgggagccct
61 ggccctgacc gagacctggg ccggctccca ctccatgagg tatttctaca ccgctgtgtc
121 ccggcccggc cgcggggagc cccacttcat cgcagtgggc tacgtggacg acacgcagtt
181 cgtgcggttc gacagcgacg ccgcgagtcc gagaggggag ccgcgggcgc cgtgggtgga
241 gcaggagggg ccggagtatt gggaccggga gacacagaag tacaagcgcc aggcacagac
301 tgaccgagtg agcctgcgga acctgcgcgg ctactacaac cagagcgagg ccaggtctca
361 catcatccag aggatgtatg gctgcgacgt ggggcccgac gggcgcctcc tccgcgggta
421 tgaccagtac gcctacgacg gcaaggatta catcgccctg aacgaggatc tgcgctcctg
481 gaccgccgcg gacacggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgaggc
541 ggagcagctg agagcctacc tggagggcct gtgcgtggag tggctccgca gatacctgaa
601 gaatgggaag gagacgctgc agcgcgcgga acacccaaag acacacgtga cccaccatcc
661 cgtctctgac catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat
721 cacactgacc tggcagtggg atggggagga ccaaactcag gacactgagc ttgtggagac
781 caggccagca ggagatggaa ccttccagaa gtgggcagct gtggtggtgc cttctggaga
841 agagcagaga tacacgtgcc atgtgcagca cgaggggctg ccggagcccc tcaccctgag
901 atgggagccg tcttcccagc ccaccatccc catcgtgggc atcgttgctg gcctggctgt
961 cctggctgtc ctagctgtcc taggagctgt ggtggctgtt gtgatgtgta ggaggaagag
1021 ctcagggcat tttcttccca caggtggaaa aggagggagc tgctctcagg ctgcgtccag
1081 caacagtgcc cagggctctg atgagtctct catcgcttgt aaagcctgag acagctgcct
1141 gtgtgggact gagatgcagg atttcttcac acctctcctt tgtgacttca agagcctctg
1201 gcatctcttt ctgcaaaggc atctgaatgt gtctgcgttc ctgttagcat aatgtgagga
1261 ggtggacaga cagcccaccc ccgtgtccac cgtgacccct gtccccacac tgacctgtgt
1321 tccctccccg atcatctttc ctgttccaga gaagtgggct ggatgtctcc atctctgtct
1381 caacttcatg gtgcgctgag ctgcaacttc ttacttccct aatgaagtta ggaacctgaa
1441 tataaatttg ttttctcaaa tatttgctat gaagggttga tggattaatt aaataagtca
1501 attcctggaa gttgagagag caaataaaga cctgagaact ttccaaaaaa aaaaaaaaaa
1561 aaaaaaaaaa aaaa
//