LOCUS BC008280 1846 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens prostaglandin E synthase, mRNA (cDNA clone MGC:10317
IMAGE:3623516), complete cds.
ACCESSION BC008280
VERSION BC008280.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1846)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1846)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: c Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38505195.
FEATURES Location/Qualifiers
source 1..1846
/db_xref="H-InvDB:HIT000033693"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10317 IMAGE:3623516"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1846
/gene="PTGES"
/gene_synonym="MGC10317"
/gene_synonym="MGST-IV"
/gene_synonym="MGST1-L1"
/gene_synonym="PGES"
/gene_synonym="PIG12"
/gene_synonym="PP102"
/gene_synonym="PP1294"
/gene_synonym="TP53I12"
/db_xref="GeneID:9536"
/db_xref="HGNC:HGNC:9599"
/db_xref="MIM:605172"
CDS 36..494
/gene="PTGES"
/gene_synonym="MGC10317"
/gene_synonym="MGST-IV"
/gene_synonym="MGST1-L1"
/gene_synonym="PGES"
/gene_synonym="PIG12"
/gene_synonym="PP102"
/gene_synonym="PP1294"
/gene_synonym="TP53I12"
/codon_start=1
/product="prostaglandin E synthase"
/protein_id="AAH08280.1"
/db_xref="GeneID:9536"
/db_xref="HGNC:HGNC:9599"
/db_xref="MIM:605172"
/translation="MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAF
ANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMH
FLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL"
BASE COUNT 417 a 498 c 492 g 439 t
ORIGIN
1 tgatcacacc cacagttgag ctgcgctggc cagagatgcc tgcccacagc ctggtgatga
61 gcagcccggc cctcccggcc ttcctgctct gcagcacgct gctggtcatc aagatgtacg
121 tggtggccat catcacgggc caagtgaggc tgcggaagaa ggcctttgcc aaccccgagg
181 atgccctgag acacggaggc ccccagtatt gcaggagcga ccccgacgtg gaacgctgcc
241 tcagggccca ccggaacgac atggagacca tctacccctt ccttttcctg ggcttcgtct
301 actcctttct gggtcctaac ccttttgtcg cctggatgca cttcctggtc ttcctcgtgg
361 gccgtgtggc acacaccgtg gcctacctgg ggaagctgcg ggcacccatc cgctccgtga
421 cctacaccct ggcccagctc ccctgcgcct ccatggctct gcagatcctc tgggaagcgg
481 cccgccacct gtgaccagca gctgatgcct ccttggccac cagaccatgg gccaagagcc
541 gccgtggcta tacctgggga cttgatgttc cttccagatt gtggtgggcc ctgagtcctg
601 gtttcctggc agcctgctgc gcgtgtgggt ctctgggcac agtgggcctg tgtgtgtgcc
661 cgtgtgtgtg tatgtgtatg tgtgtgtgta tgtttcttag ccccttggat tcctgcacga
721 agtggctgat gggaaccatt tcaagacaga ttgtgaagat tgatagaaaa tccttcagct
781 aaagtaacag agcatcaaaa acatcactcc ctctccctcc ctaacagtga aaagagagaa
841 gggagactct atttaagatt cccaaaccta atgatcatct gaatcccggg ctaagaatgc
901 agacttttca gactgacccc agaaattctg gcccagccaa tctagaggca agcctggcca
961 tctgtatttt tttttttcca agacagagtc ttgctctgtt gcccaagctg gagtgaagtg
1021 gtacaatctg gctcactgca gcctccgcct cccgggttca agcgattctc ccgcctcagc
1081 ctcctgagta gctgggatta caggcgcgta tcaccatacc cagctaattt ttgtattttt
1141 agtagagacg ggttcaccat gttgcccagg agggtctcga actcctggcc tcaagtgatc
1201 caccggcctc ggcctcccaa agtgctggga tgacaggcat gaatcactgt gctcagccac
1261 catctggagt tttaaaaggc tcccatgtga gtccctgtga tggccaggcc aggggacccc
1321 tgccagttct ctgtggaagc aaggctgggg tcttgggttc ctgtatggtg gaagctgggt
1381 gagccaagga cagggctggc tcctctgccc ccgctgacgc ttcccttgcc gttggctttg
1441 gatgtctttg ctgcagtctt ctctctggct caggtgtggg tgggaggggc ccacaggaag
1501 ctcagccttc tcctcccaag gtttgagtcc ctccaaaggg cagtgggtgg aggaccggga
1561 gctttgggtg accagccact caaaggaact ttctggtccc ttcagtatct tcaaggtttg
1621 gaaactgcaa atgtcccctt gatggggaat ccgtgtgtgt gtgtgtgtgt gtgtgtgtgt
1681 gtgtgtgtgt gtgtgttttc tcctagaccc gtgacctgag atgtgtgatt tttagtcatt
1741 aaatggaagt gtctgccaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//