LOCUS BC008076 3195 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens bromodomain containing 8, mRNA (cDNA clone MGC:3524
IMAGE:3009915), complete cds.
ACCESSION BC008076
VERSION BC008076.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3195)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3195)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (21-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC008076.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 10 Row: o Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21264559.
FEATURES Location/Qualifiers
source 1..3195
/db_xref="H-InvDB:HIT000033633"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3524 IMAGE:3009915"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3195
/gene="BRD8"
/gene_synonym="P120"
/gene_synonym="SMAP"
/db_xref="GeneID:10902"
/db_xref="MIM:602848"
CDS 91..2853
/gene="BRD8"
/gene_synonym="P120"
/gene_synonym="SMAP"
/codon_start=1
/product="BRD8 protein"
/protein_id="AAH08076.1"
/db_xref="GeneID:10902"
/db_xref="MIM:602848"
/translation="MRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETT
ETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGH
MDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDS
ASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPV
TDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLL
EVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEP
PVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHT
VTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTG
EELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQE
RDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEI
VAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPES
MLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAA
SLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSV
CSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLST
IKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLAT
QLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFDGGTRGRRCAIEA
DMKMKK"
misc_feature 2341..2652
/gene="BRD8"
/gene_synonym="P120"
/gene_synonym="SMAP"
/note="BROMO; Region: bromo domain"
/db_xref="CDD:smart00297"
BASE COUNT 934 a 736 c 816 g 709 t
ORIGIN
1 gcgacgggaa cgggcaaaca caagctgcta agcactggcc ccacagagcc atggtccatc
61 cgagagaagc tatgtttagc atcttctgtc atgagaagtg gcgatcaaaa ttgggtatca
121 gttagcagag caatcaagcc ctttgcagaa cctggccgcc ctccagactg gttctctcaa
181 aaacattgtg cttcccagta ctcggagctt ttagagacca ctgagacacc aaaacggaaa
241 cgaggtgaaa agggagaagt ggtggaaact gttgaagatg ttattgttcg gaaattgact
301 gctgagcgag ttgaagaact aaagaaagtg ataaaggaaa cccaggagag atatagacgg
361 ctaaagagag atgcagaact aattcaagct ggacacatgg acagcagact ggatgagctt
421 tgcaatgaca ttgcaacgaa aaagaaattg gaagaagagg aggctgaagt aaagaggaag
481 gctacagatg ctgcatacca ggctcgtcaa gcagtaaaaa cacccccccg gaggttaccc
541 actgtgatgg ttcgctctcc tatagattct gcctccccag gaggtgatta tccacttggg
601 gacttgactc caaccactat ggaagaggct acctctgggg taacccccgg gactttgccg
661 agtaccccag tcacctcgtt tcctgggatt cctgacaccc ttcctccagg ctctgcaccc
721 ttagaagccc ccatgacccc agtaacagat gattcacccc agaaaaagat gcttggacag
781 aaagcaactc cacccccctc ccctctgctg tcagagctct tgaagaaggg cagcctcctg
841 cctactagcc ccagactggt caatgagagt gaaatggctg tggcttctgg ccacctgaac
901 agtacaggtg tcctcctgga ggtaggcggg gtccttccca tgatacatgg tggggagata
961 cagcaaacac ccaatactgt tgcagcctcc cctgctgcat caggtgctcc cactctttcc
1021 cggcttttag aagctggtcc tacacagttc accacacctc ttgcttcctt cactactgtt
1081 gccagtgagc ctccagttaa acttgtgcca ccccctgtag agtctgtgtc ccaagctacc
1141 attgtcatga tgcctgcgct gccagcacca tcctctgctc cggctgtctc cactactgaa
1201 agtgtagctc cagtgagtca acccgacaac tgtgttccca tggaggctgt gggggatcca
1261 catactgtga ctgtttccat ggacagcagt gaaatatcca tgatcatcaa ttctatcaaa
1321 gaagagtgtt ttcgatcagg ggtagcagag gctcctgttg gatcaaaggc tcccagcata
1381 gatgggaagg aagaattaga tctggctgag aagatggata ttgctgtgtc ttacacaggt
1441 gaagagctgg attttgagac tgttggagac atcattgcca tcattgagga caaggtagat
1501 gatcatcctg aagtgctgga tgtggcagca gtggaagcag cactgtcatt ttgtgaagaa
1561 aatgatgatc ctcagtccct gcctggcccc tgggagcatc ctatccagca ggagcgggac
1621 aagccagtac ctctccctgc accagaaatg acggtcaagc aagagagact ggactttgag
1681 gaaacggaaa acaagggaat acatgaactg gtggacatca gggagcccag tgcagagatc
1741 aaggtggaac ctgcagaacc agagccagtc atttcaggag ccgaaatagt agctggagtt
1801 gttccagcca caagtatgga gccaccagaa ctcaggagtc aggacttaga tgaggaactg
1861 ggaagtactg cagctggaga gattgttgaa gcagatgttg ccattgggaa aggcgatgag
1921 actccactta caaatgtgaa gacagaggca tcccctgaaa gcatgttgtc tccatcacat
1981 ggctcaaatc ccattgaaga tcctttagag gcagagactc agcacaagtt tgaaatgtca
2041 gactcattga aagaagaatc agggactatt tttggaagcc agataaagga tgccccaggt
2101 gaggatgagg aggaagatgg tgtcagtgaa gcggccagcc tagaggagcc taaggaagag
2161 gatcaaggag aaggctactt gtcagaaatg gataatgaac ctcctgtgag cgagagtgat
2221 gatggcttca gcatacacaa tgctacactg cagtcacaca cactggcaga ctccatcccc
2281 agcagccctg cttcttcaca gttctctgtc tgtagtgagg atcaggaagc tattcaggca
2341 cagaaaattt ggaagaaagc catcatgctt gtatggagag ctgcagctaa tcataggtat
2401 gccaatgtct tcctgcagcc tgttacagat gacatagcac ctggctacca cagcattgtg
2461 cagaggccta tggatttgtc aactattaag aaaaacatag aaaatggact gatccgaagc
2521 acagctgaat ttcagcgtga cattatgctg atgtttcaga atgctgtaat gtacaatagc
2581 tcagaccatg atgtctatca catggcagtg gagatgcagc gagatgtctt ggaacagatc
2641 cagcaattct tggccacgca gttgattatg caaacatccg agtctgggat cagtgctaaa
2701 agtcttcgag ggagagattc tacccgcaaa caggatgctt cagagaagga cagtgtccca
2761 atgggctctc ctgccttcct tctctctctc tttgatggag gaaccagggg acgccgctgt
2821 gccattgaag cagatatgaa gatgaaaaag tgaagcctca gagttaccct ctttgagccg
2881 aacctaaaat aaaagtaaac aagatagagc ttgggcttgc gggcccagtt ccagaggtgg
2941 aagttacaga agaggaggta cctgggccac acgacatgag ctggaaaatc tctcttagag
3001 agttggagta gcacaattgc ctgttttagg gcagaaacca tgggctatgt taatgtccta
3061 atgtgtagct agcagatcgt agctagtttg tattgtcttg tcaattgtac agacttttta
3121 aaaaaaacaa ccaccagtga aatgtgtgtg tatacaataa actgaaaaaa aaaactaaaa
3181 aaaaaaaaaa aaaaa
//