LOCUS BC008037 2171 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens protein kinase C and casein kinase substrate in
neurons 2, mRNA (cDNA clone MGC:1214 IMAGE:2967052), complete cds.
ACCESSION BC008037
VERSION BC008037.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2171)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2171)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (21-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC008037.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: o Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6005825.
FEATURES Location/Qualifiers
source 1..2171
/db_xref="H-InvDB:HIT000033604"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1214 IMAGE:2967052"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2171
/gene="PACSIN2"
/db_xref="GeneID:11252"
/db_xref="MIM:604960"
CDS 223..1683
/gene="PACSIN2"
/codon_start=1
/product="PACSIN2 protein"
/protein_id="AAH08037.1"
/db_xref="GeneID:11252"
/db_xref="MIM:604960"
/translation="MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNC
LHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKA
SLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHH
AACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQG
TPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRA
ADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKATDGVTLTGINQTGD
QSLPSKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQ
SYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAG
DELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ"
misc_feature 274..534
/gene="PACSIN2"
/note="FCH; Region: Fes/CIP4 homology domain. Alignment
extended from. Highly alpha-helical"
/db_xref="CDD:pfam00611"
misc_feature 1504..1677
/gene="PACSIN2"
/note="SH3; Region: Src homology 3 domains"
/db_xref="CDD:smart00326"
BASE COUNT 602 a 538 c 642 g 389 t
ORIGIN
1 ctgtcccact gggcaggtgc ctctgacgga gaggaggcgt cgtcgggaag tatgtggccg
61 tggctgctct ggcatgatcc tgaagactgg cacgaagggg aatggagccg cacagagaat
121 ttcaggcatc agaggggaag cgcaggtttg tctacagatt ttgagcgttc gaagttgacc
181 cctgactaag tatactttgc tgctccctca gcctttgaaa aaatgtctgt cacatatgat
241 gattccgttg gagtagaagt gtccagcgac agcttctggg aggtcgggaa ctacaagcgg
301 actgtgaagc ggatcgacga tggccaccgc ctgtgcagcg acctcatgaa ctgcctgcat
361 gagcgggcgc gcatcgagaa ggcgtatgcg cagcagctca ctgagtgggc ccggcgctgg
421 aggcagctcg tggagaaagg gccccagtac gggaccgtgg agaaggcctg gatggccttc
481 atgtccgagg cagagagggt gagcgagctg cacctcgagg tgaaggcctc actgatgaac
541 gatgacttcg agaagatcaa gaactggcag aaggaagcct ttcacaagca gatgatgggc
601 ggcttcaagg agaccaagga agctgaggac ggctttcgga aggcacagaa gccctgggcc
661 aagaagctga aagaggtaga agcagcaaag aaagcccacc atgcagcgtg caaagaggag
721 aagctggcta tctcacgaga agccaacagc aaggcagacc catccctcaa ccctgaacag
781 ctcaagaaat tgcaagacaa aatagaaaag tgcaagcaag atgttcttaa gaccaaagag
841 aagtatgaga agtccctgaa ggaactcgac cagggcacac cccagtacat ggagaacatg
901 gagcaggtgt ttgagcagtg ccagcagttc gaggagaaac gccttcgctt cttccgggag
961 gttctgctgg aggttcagaa gcacctagac ctgtccaatg tggctggcta caaagccatt
1021 taccatgacc tggagcagag catcagagca gctgatgcag tggaggacct gaggtggttc
1081 cgagccaatc acgggccggg catggccatg aactggccgc agtttgagga gtggtccgca
1141 gacctgaatc gaaccctcag ccggagagag aagaagaagg ccactgacgg cgtcaccctg
1201 acgggcatca accagacagg cgaccagtct ctgccgagta agcccagcag cacccttaat
1261 gtcccgagca accccgccca gtctgcgcag tcacagtcca gctacaaccc cttcgaggat
1321 gaggacgaca cgggcagcac cgtcagtgag aaggacgaca ctaaggccaa aaatgtgagc
1381 agctacgaga agacccagag ctatcccacc gactggtcag acgatgagtc taacaacccc
1441 ttctcctcca cggatgccaa tggggactcg aatccattcg acgacgacgc cacctcgggg
1501 acggaagtgc gagtccgggc cctgtatgac tatgaggggc aggagcatga tgagctgagc
1561 ttcaaggctg gggatgagct gaccaagatg gaggacgagg atgagcaggg ctggtgcaag
1621 ggacgcttgg acaacgggca agttggccta tacccggcaa attatgtgga ggcgatccag
1681 tgatgagtcg gggacaggcc agcgggggga cggaggcggc gggcccagga gcctcagcca
1741 gccacgtggg catccactcc ttttcctgca agagatgatg gttccattgc tcttggcttc
1801 atggtgttcc tggaaggcag atgagctggt catttcgcct gggactcggc acctttccga
1861 gtgcagctgg agggatctga gcgcaggaag acgcagaaca acagaaatag ccgcccctcc
1921 ccgcccactg tgcctgttgg cctatcatag atctctatgt tcttgacttt gtctctcctt
1981 tccgagtcaa tggtgggtta cactgatctt gttccactga ttactctctc tgacgagtcc
2041 atcacctgca acttaaatga acaagcttac atcccatttt gagtgaagat tttgaggttt
2101 ttaatttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa a
//