LOCUS BC007981 2291 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serine/threonine kinase 11, mRNA (cDNA clone MGC:16254
IMAGE:3689780), complete cds.
ACCESSION BC007981
VERSION BC007981.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2291)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2291)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007981.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 24 Row: i Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58530881.
FEATURES Location/Qualifiers
source 1..2291
/db_xref="H-InvDB:HIT000033568"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:16254 IMAGE:3689780"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2291
/gene="STK11"
/gene_synonym="LKB1"
/gene_synonym="PJS"
/db_xref="GeneID:6794"
/db_xref="HGNC:HGNC:11389"
/db_xref="MIM:602216"
CDS 451..1752
/gene="STK11"
/gene_synonym="LKB1"
/gene_synonym="PJS"
/codon_start=1
/product="serine/threonine kinase 11"
/protein_id="AAH07981.1"
/db_xref="GeneID:6794"
/db_xref="HGNC:HGNC:11389"
/db_xref="MIM:602216"
/translation="MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAK
LIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLL
RRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQL
IDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPA
FQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPG
DCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRS
MTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCM
NGTEAAQLSTKSRAEGRAPNPARKACSASSKIRRLSACKQQ"
BASE COUNT 452 a 705 c 729 g 405 t
ORIGIN
1 ggcctgtggg atgggcggcc cggagaagac tgcgctcggc cgtgttcata cttgtccgtg
61 ggcctgaggt ccccggagga tgacctagca ctgaaaagcc ccggccggcc tccccagggt
121 ccccgaggac gaagttgacc ctgaccgggc cgtctcccag ttctgaggcc cgggtcccac
181 tggaactcgc gtctgagccg ccgtcccgga cccccggtgc ccgccggtcc gcagaccctg
241 caccgggctt ggactcgcag ccgggactga cgtgtagaac aatcgtttct gttggaagaa
301 gggtttttcc cttccttttg gggtttttgt tgcctttttt ttttcttttt tctttgtaaa
361 attttggaga agggaagtcg gaacacaagg aaggaccgct cacccgcgga ctcagggctg
421 gcggcgggac tccaggaccc tgggtccagc atggaggtgg tggacccgca gcagctgggc
481 atgttcacgg agggcgagct gatgtcggtg ggtatggaca cgttcatcca ccgcatcgac
541 tccaccgagg tcatctacca gccgcgccgc aagcgggcca agctcatcgg caagtacctg
601 atgggggacc tgctggggga aggctcttac ggcaaggtga aggaggtgct ggactcggag
661 acgctgtgca ggagggccgt caagatcctc aagaagaaga agttgcgaag gatccccaac
721 ggggaggcca acgtgaagaa ggaaattcaa ctactgagga ggttacggca caaaaatgtc
781 atccagctgg tggatgtgtt atacaacgaa gagaagcaga aaatgtatat ggtgatggag
841 tactgcgtgt gtggcatgca ggaaatgctg gacagcgtgc cggagaagcg tttcccagtg
901 tgccaggccc acgggtactt ctgtcagctg attgacggcc tggagtacct gcatagccag
961 ggcattgtgc acaaggacat caagccgggg aacctgctgc tcaccaccgg tggcaccctc
1021 aaaatctccg acctgggcgt ggccgaggca ctgcacccgt tcgcggcgga cgacacctgc
1081 cggaccagcc agggctcccc ggctttccag ccgcccgaga ttgccaacgg cctggacacc
1141 ttctccggct tcaaggtgga catctggtcg gctggggtca ccctctacaa catcaccacg
1201 ggtctgtacc ccttcgaagg ggacaacatc tacaagttgt ttgagaacat cgggaagggg
1261 agctacgcca tcccgggcga ctgtggcccc ccgctctctg acctgctgaa agggatgctt
1321 gagtacgaac cggccaagag gttctccatc cggcagatcc ggcagcacag ctggttccgg
1381 aagaaacatc ctccggctga agcaccagtg cccatcccac cgagcccaga caccaaggac
1441 cggtggcgca gcatgactgt ggtgccgtac ttggaggacc tgcacggcgc ggacgaggac
1501 gaggacctct tcgacatcga ggatgacatc atctacactc aggacttcac ggtgcccgga
1561 caggtcccag aagaggaggc cagtcacaat ggacagcgcc ggggcctccc caaggccgtg
1621 tgtatgaacg gcacagaggc ggcgcagctg agcaccaaat ccagggcgga gggccgggcc
1681 cccaaccctg cccgcaaggc ctgctccgcc agcagcaaga tccgccggct gtcggcctgc
1741 aagcagcagt gaggctggcc gcctgcagcc cgtgtccagg agccccgcca ggtgcccgcg
1801 ccaggccctc agtcttcctg ccggttccgc ccgccctccc ggagaggtgg ccgccatgct
1861 tctgtgccga ccacgcccca ggacctccgg agcgccctgc agggccgggc agggggacag
1921 cagggaccgg gcgcagccct cccccctcgg ccgcccggca gtgcacgcgg cttgttgact
1981 tcgcagcccc gggcggagcc ttcccgggcg ggcgtgggag gagggaggcg gcctccatgc
2041 actttatgtg gagactactg gccccgcccg tggcctcgtg ctccgcaggg cgcccagcgc
2101 cgtccggcgg ccccgccgca gaccagctgg cgggtgtgga gaccaggctc ctgaccccgc
2161 catgcatgca gcgccacctg gaagccgcgc ggccgctttg gttttttgtt tggttggttc
2221 cattttcttt ttttcttttt ttttttaaga aaaaataaaa ggtggatttg aaaaaaaaaa
2281 aaaaaaaaaa a
//