LOCUS BC007979 2407 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serine hydroxymethyltransferase 1 (soluble), mRNA
(cDNA clone MGC:15229 IMAGE:3687873), complete cds.
ACCESSION BC007979
VERSION BC007979.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2407)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2407)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007979.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 24 Row: g Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22547185.
FEATURES Location/Qualifiers
source 1..2407
/db_xref="H-InvDB:HIT000033566"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15229 IMAGE:3687873"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2407
/gene="SHMT1"
/gene_synonym="CSHMT"
/gene_synonym="MGC15229"
/gene_synonym="MGC24556"
/gene_synonym="SHMT"
/db_xref="GeneID:6470"
/db_xref="HGNC:HGNC:10850"
/db_xref="MIM:182144"
CDS 58..1509
/gene="SHMT1"
/gene_synonym="CSHMT"
/gene_synonym="MGC15229"
/gene_synonym="MGC24556"
/gene_synonym="SHMT"
/codon_start=1
/product="serine hydroxymethyltransferase 1 (soluble)"
/protein_id="AAH07979.1"
/db_xref="GeneID:6470"
/db_xref="HGNC:HGNC:10850"
/db_xref="MIM:182144"
/translation="MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQ
RVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQ
AYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKI
SATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIA
DENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSV
DPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVAN
CRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGD
RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKE
RLAGDKYQAAVQALREEVESFASFFPLPGLPDF"
BASE COUNT 636 a 598 c 613 g 560 t
ORIGIN
1 caggcaccgg cggcggcgta ggacggaggc gtcgctaggc agcttcgaac cagtgcaatg
61 acgatgccag tcaacggggc ccacaaggat gctgacctgt ggtcctcaca tgacaagatg
121 ctggcacaac ccctcaaaga cagtgatgtt gaggtttaca acatcattaa gaaggagagt
181 aaccggcaga gggttggatt ggagctgatt gcctcggaga atttcgccag ccgagcagtt
241 ttggaggccc taggctcttg cttaaataac aaatactctg aggggtaccc gggccagaga
301 tactatggcg ggactgagtt tattgatgaa ctggagaccc tctgtcagaa gcgagccctg
361 caggcctata agctggaccc acagtgctgg ggggtcaacg tccagcccta ctcaggctcc
421 cctgcaaact ttgctgtgta cactgccctg gtggaacccc atgggcgcat catgggcctg
481 gaccttccgg atgggggcca cctgacccat gggttcatga cagacaagaa gaaaatctct
541 gccacgtcca tcttctttga atctatgccc tacaaggtga acccagatac tggctacatc
601 aactatgacc agctggagga gaacgcacgc ctcttccacc cgaagctgat catcgcagga
661 accagctgct actcccgaaa cctggaatat gcccggctac ggaagattgc agatgagaac
721 ggggcgtatc tcatggcgga catggctcac atcagcgggc tggtggcggc tggcgtggtg
781 ccctccccat ttgaacactg ccatgtggtg accaccacca ctcacaagac cctgcgaggc
841 tgccgagctg gcatgatctt ctacaggaaa ggagtgaaaa gtgtggatcc caagactggc
901 aaagagattc tgtacaacct ggagtctctt atcaattctg ctgtgttccc tggcctgcag
961 ggaggtcccc acaaccacgc cattgctggg gttgctgtgg cactgaagca agctatgact
1021 ctggaattta aagtttatca acaccaggtg gtggccaact gcagggctct gtctgaggcc
1081 ctgacggagc tgggctacaa aatagtcaca ggtggttctg acaaccattt gatccttgtg
1141 gatctccgtt ccaaaggcac agatggtgga agggctgaga aggtgctaga agcctgttct
1201 attgcctgca acaagaacac ctgtccaggt gacagaagcg ctctgcggcc cagtggactg
1261 cggctgggga ccccagcact gacgtcccgt ggacttttgg aaaaagactt ccaaaaagta
1321 gcccacttta ttcacagagg gatagagctg accctgcaga tccagagcga cactggtgtc
1381 agagccaccc tgaaagagtt caaggagaga ctggcagggg ataagtacca ggcggccgtg
1441 caggctctcc gggaggaggt tgagagcttc gcctctttct tccctctgcc tggcctgcct
1501 gacttctaaa ggagcgggcc cactctggac ccacctggcg ccacagagga agctggctgc
1561 cggaggaccc ccacttgaga gatggatgag ctgctccaaa ggggaactgt tgacactcgg
1621 gccctttgag ggggtttctt ttggactttt ttcatgtttt cttcacaaat caaaatttgt
1681 ttaagtctca ttgttagtaa ttctgggaca ggttattaaa ggatttaaat ttgaacctgg
1741 ctttctcaca gctggacata attctaggaa aataagatac tatgtcgcca cttggtcata
1801 atcatttaga tggtggtgta gggcaaagct gttagaaaga ttgtagcgtt ttactctccc
1861 tgggctttcc tccgccttgc tgcaacagag aggaaatgcc catgtccaca gcttgtacac
1921 actgccccct cactatcttg ttatccagtg gcatgccaaa ggagaactga attagcttct
1981 gaggcttctg ctgtaaatca gaagtgtatg ttagtcaaga gtaaacaaga tgcacccagt
2041 atggtgggag ggttttgctg tcagtagctc aaagtatggt gtagaaatgg cctcctccct
2101 ccatcctggg aagtcccagt cccatcctgg tgtgagaatc aaccaggctt tcctgctcca
2161 cctgagataa ccaactccct cccgtaatca ggaagccaaa tgtcaccttc ccaaagaaat
2221 tttattttca cgtagctgaa gtgcaaaaca tagatgacca tttttaataa gcacaatcaa
2281 atttttaacc acagaatgtc tacaagaatt atagctttaa aaaatacaac caatttttat
2341 atttcaaaaa tatttgaact caaataaatt aatttcttaa aaagtaaaaa aaaaaaaaaa
2401 aaaaaaa
//