LOCUS BC007891 2496 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens selenocysteine lyase, mRNA (cDNA clone MGC:14083
IMAGE:4126478), complete cds.
ACCESSION BC007891
VERSION BC007891.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2496)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2496)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC007891.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: f Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39725671.
FEATURES Location/Qualifiers
source 1..2496
/db_xref="H-InvDB:HIT000033516"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14083 IMAGE:4126478"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2496
/gene="SCLY"
/gene_synonym="SCL"
/db_xref="GeneID:51540"
/db_xref="HGNC:HGNC:18161"
CDS 17..1354
/gene="SCLY"
/gene_synonym="SCL"
/codon_start=1
/product="selenocysteine lyase"
/protein_id="AAH07891.1"
/db_xref="GeneID:51540"
/db_xref="HGNC:HGNC:18161"
/translation="MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEP
EVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTES
NNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQV
AAVTFVPVSKVSGQTEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQ
ERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEF
TPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERL
EAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDH
GDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA"
BASE COUNT 564 a 745 c 678 g 509 t
ORIGIN
1 cagcagtggg gcggggatgg aggcggccgt ggcgccgggg agggatgcgc cggcacccgc
61 ggcgagtcag cccagcggct gcgggaaaca caactcgccg gagaggaaag tttatatgga
121 ctataatgca acgactcccc tggagccaga agttatccag gccatgacca aggccatgtg
181 ggaagcctgg ggaaatccca gcagcccgta ttcagcagga agaaaggcca aggatattat
241 aaatgcagct cgggaaagcc tcgcgaagat gatagggggg aaacctcaag atataatctt
301 cacttccggg ggcactgagt caaataattt agtaatccat tctgtggtga aacatttcca
361 cgcaaaccag acctcaaagg gacacacagg tgggcaccac agcccagtga agggggccaa
421 gccccatttc attacttcct cggtggaaca cgactccatc cggctgcccc tggagcacct
481 ggtggaagaa caagtggcag cggtcacctt tgtcccggtg tccaaggtga gcgggcagac
541 agaggtggac gacatcctcg cggcagtccg cccgaccaca cgcctcgtga ccatcatgct
601 ggccaacaat gagactggca ttgtcatgcc tgtccctgaa atcagtcagc gcattaaagc
661 cctgaaccag gaacgggtgg cagctgggct acctcccatc ctcgtgcaca cggatgctgc
721 acaggccttg gggaagcagc gcgtggatgt ggaggacctg ggcgtggact tccttacaat
781 cgtggggcac aagttttatg gtcccaggat tggcgcactt tatatacgag gacttggtga
841 atttacccct ctctacccta tgctatttgg aggtggacaa gaacggaatt tcaggccagg
901 gacagagaac accccaatga ttgctggcct tgggaaggcc gcggagctgg tgacccagaa
961 ctgcgaggct tatgaggccc acatgaggga cgtccgcgac tacctggaag agaggctgga
1021 agctgaattc ggtcagaaga gaatccatct gaatagccag tttccaggca cccagcggct
1081 tcccaatacc tgtaactttt ccatccgggg accccggctt caaggccacg tggtgcttgc
1141 gcagtgccga gtgctgatgg ccagtgtggg ggccgcgtgc cactcggacc acggggacca
1201 gccgtcccca gtgctgctga gctacggtgt ccccttcgac gtggccagga acgcgctccg
1261 gctcagcgtg ggccgcagca ccaccagggc cgaggtggac ctcgtcgtgc aggacctgaa
1321 gcaggccgtg gcgcagctgg aggaccaggc ctagcactgg ggccgccttc cccaccccgc
1381 ttctgggaag cccgtggcag ggcacagggt tgtccctcca gttccctcct gagggctgtg
1441 ccaggatgac tgtctcatgc cccctctgca ttttgtcctg gagtgccagc gagtgtgcac
1501 ccccagtttc cttccctgga accctgcaga gctcacaggg cccaggacac caacgccgca
1561 taggaccgcc cacatgggaa cgcccacatg ggaccgccca cataggaccg cccacatagg
1621 accgcccaca tgggaccgcc cacatagaac cgcccacata ggaccgccca catgggaacg
1681 cccacatggg accgcccaca tgggaccgcc cacatgggac cgcccacata gaaccgtcct
1741 ccagtggtga agcggaaaca cttagcttta tccaccctcc ccactgggaa ctgggcacgc
1801 ctgttgtgag tgccctttcc tggaaggtgt ttttatctgg aagatagaat ccaagtattt
1861 ataactcatt gtcagccaaa tgctatcatg aacgtaggaa acttgatttt tttgttttga
1921 tcatggcctc tacatgcacc tttccagagt ggtctcttct cgggcccttt ttagtccctt
1981 tccaaagctg cccccaccac cctgctcctc tggcctcagt gcacagtggc ccccagcctc
2041 ggccaggcct gctctgctca gcgcccaccg cccaccaccc ctcctgcttc cccgagcctg
2101 accctgttcc gcccactggc aatcagggct gcgcacttcc ctgtccacgg tccccaggcc
2161 ttcctgtctt gtcccttttg atcattaact cagggtttca gctccaacct cgctgagttg
2221 gtgcagctcc gggtcattcc tggggtggga atcggatcat ccctgactca gcttatacct
2281 taattttatt tgcagaggat tcttttctca aaatgctctg gcatttggac acacatcaca
2341 tgtcgatatt tgcataggag tcattttcag tggaataaca tttttaatgt gtggttttac
2401 ggttcaagga actacatgat gattttgagg aaacacttgc cagaaactaa attaacgaat
2461 aaaagatttc agtgcccgaa aaaaaaaaaa aaaaaa
//