LOCUS BC007740 2565 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cholinergic receptor, muscarinic 1, mRNA (cDNA clone
MGC:13136 IMAGE:4128514), complete cds.
ACCESSION BC007740
VERSION BC007740.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2565)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2565)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007740.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: h Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37622909.
FEATURES Location/Qualifiers
source 1..2565
/db_xref="H-InvDB:HIT000033414"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13136 IMAGE:4128514"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2565
/gene="CHRM1"
/gene_synonym="HM1"
/gene_synonym="M1"
/gene_synonym="MGC30125"
/db_xref="GeneID:1128"
/db_xref="HGNC:HGNC:1950"
/db_xref="MIM:118510"
CDS 123..1505
/gene="CHRM1"
/gene_synonym="HM1"
/gene_synonym="M1"
/gene_synonym="MGC30125"
/codon_start=1
/product="cholinergic receptor, muscarinic 1"
/protein_id="AAH07740.1"
/db_xref="GeneID:1128"
/db_xref="HGNC:HGNC:1950"
/db_xref="MIM:118510"
/translation="MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNL
LVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWL
ALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPA
ILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENR
ARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKE
EEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGR
DRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCK
DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPG
SVHRTPSRQC"
BASE COUNT 541 a 849 c 702 g 473 t
ORIGIN
1 ggcagtgggg ttgaggaccc tacagacccc tcttcagccc cgtggtgatg actttcccct
61 gaggaagccc tgtagcgtgc ctggaggaag gggctctcca accccagccc cacctagcca
121 ccatgaacac ttcagcccca cctgctgtca gccccaacat caccgtcctg gcaccaggaa
181 agggtccctg gcaagtggcc ttcattggga tcaccacggg cctcctgtcg ctagccacag
241 tgacaggcaa cctgctggta ctcatctctt tcaaggtcaa cacggagctc aagacagtca
301 ataactactt cctgctgagc ctggcctgtg ctgacctcat catcggtacc ttctccatga
361 acctctatac cacgtacctg ctcatgggcc actgggctct gggcacgctg gcttgtgacc
421 tctggctggc cctggactat gtggccagca atgcctccgt catgaatctg ctgctcatca
481 gctttgaccg ctacttctcc gtgactcggc ccctgagcta ccgtgccaag cgcacacccc
541 gccgggcagc tctgatgatc ggcctggcct ggctggtttc ctttgtgctc tgggccccag
601 ccatcctctt ctggcagtac ctggtagggg agcggacagt gctagctggg cagtgctaca
661 tccagttcct ctcccagccc atcatcacct ttggcacagc catggctgcc ttctacctcc
721 ctgtcacagt catgtgcacg ctctactggc gcatctaccg ggagacagag aaccgagcac
781 gggagctggc agcccttcag ggctccgaga cgccaggcaa agggggtggc agcagcagca
841 gctcagagag gtctcagcca ggggctgagg gctcaccaga gactcctcca ggccgctgct
901 gtcgctgctg ccgggccccc aggctgctgc aggcctacag ctggaaggaa gaagaggaag
961 aggacgaagg ctccatggag tccctcacat cctcagaggg agaggagcct ggctccgaag
1021 tggtgatcaa gatgccaatg gtggaccccg aggcacaggc ccccaccaag cagcccccac
1081 ggagctcccc aaatacagtc aagaggccga ctaagaaagg gcgtgatcga gctggcaagg
1141 gccagaagcc ccgtggaaag gagcagctgg ccaagcggaa gaccttctcg ctggtcaagg
1201 agaagaaggc ggctcggacc ctgagtgcca tcctcctggc cttcatcctc acctggacac
1261 cgtacaacat catggtgctg gtgtccacct tctgcaagga ctgtgttccc gagaccctgt
1321 gggagctggg ctactggctg tgctacgtca acagcaccat caaccccatg tgctacgcac
1381 tctgcaacaa agccttccgg gacacctttc gcctgctgct gctttgccgc tgggacaaga
1441 gacgctggcg caagatcccc aagcgccctg gctccgtgca ccgcactccc tcccgccaat
1501 gctgatagtc ccctctcctg catccctcca ccccagtccc cgggaaaggc cggtgggaag
1561 agggcagggg ctgcatcctc agccccaggg ccctgctcag gcctcacctg gcttcccagg
1621 accctgggtc accttcctgg gcagcccaga gagaccctgc caactttcca gacttcgcta
1681 ttcccaggca gggagggaaa cccggggaac tggtttttct gttccctgct gggtgggaat
1741 gcgctcttca ccaggaagaa ggcccgggag gaggatccgg gctttggact ccttgtttgc
1801 ctttaggcag gaagtcagga gccagcaggg cgggccagga gaaagaaggc ttaacattaa
1861 gtattccttg gcccagcagc ggcccagatt gcggtgtgag atggtgcccc ctggggggca
1921 cagccagaaa ctgaactggc cgctgggaga aaagccagat gacagggagc tggggaatcc
1981 cctcgcttca taggcagagc ccgcccacct gggccctagg catactctcc aggattgtcc
2041 acaaatgtcc tcagagggtc cctaggtggg tcaactccaa ggcaaatgtc caagcatcag
2101 caagacaatg acactggaag ggtccggctt ggctagtcac atatcaagtc ccgaggcagc
2161 aacaggacca ggagccaggt gtcctgactg tcctacaata tcattttcct gggagtggga
2221 gtcaagtgtg cctgctatcc agccgcaaat ccataccccc tgccccagag aagcctcagt
2281 ccctccctcc tggctcacag ccaccacctg gatggatctg ctccatgcag atctagccag
2341 gcctcccgca tgctgcctgc ctccggccct gccccacaca ggcctggccc agccagcagg
2401 ttctctcctg tgagctcccc aatccaaccc atgcatggcc tcccagccac ccggatctcc
2461 aggcccagcc tggccccaaa tgttctttcc tttcatcctc agcaagtgct gagtctgtga
2521 ataaagccac ataaccagcg ggcaaaaaaa aaaaaaaaaa aaaaa
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