LOCUS BC007725 1837 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ceroid-lipofuscinosis, neuronal 8 (epilepsy,
progressive with mental retardation), mRNA (cDNA clone MGC:12845
IMAGE:4303103), complete cds.
ACCESSION BC007725
VERSION BC007725.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1837)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1837)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007725.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: o Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31083052.
FEATURES Location/Qualifiers
source 1..1837
/db_xref="H-InvDB:HIT000033404"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12845 IMAGE:4303103"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1837
/gene="CLN8"
/db_xref="GeneID:2055"
/db_xref="HGNC:HGNC:2079"
/db_xref="MIM:607837"
CDS 160..1020
/gene="CLN8"
/codon_start=1
/product="ceroid-lipofuscinosis, neuronal 8 (epilepsy,
progressive with mental retardation)"
/protein_id="AAH07725.1"
/db_xref="GeneID:2055"
/db_xref="HGNC:HGNC:2079"
/db_xref="MIM:607837"
/translation="MNPASDGGTSESIFDLDYASWGIRSTLMVAGFVFYLGVFVVCHQ
LSSSLNATYRSLVAREKVFWDLAATRAVFGVQSTAAGLWALLGDPVLHADKARGQQNW
CWFHITTATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFLGFLGCLVNLQAGHYLA
MTTLLLEMSTPFTCVSWMLLKAGWSESLFWKLNQWLMIHMFHCRMVLTYHMWWVCFWH
WDGLVSSLYLPHLTLFLVGLALLTLIINPYWTHKKTQQLLNPVDWNFAQPEAKSRPEG
NGQLLRKKRP"
BASE COUNT 407 a 455 c 508 g 467 t
ORIGIN
1 gccaagcgca gggagcccgg ctgagtggca gcccagattg aagatggata cgtgacaatc
61 ccagggaccg ctgcactgac ttcatttcct tagacaagac acagtgtagg gcccggcccg
121 tgttggcccc aggactcctt tggaatatag ctgtggacaa tgaatcctgc gagcgatggg
181 ggcacatcag agagcatttt tgacctggac tatgcatcct gggggatccg ctccacgctg
241 atggtcgctg gctttgtctt ctacttgggc gtctttgtgg tctgccacca gctgtcctct
301 tccctgaatg ccacttaccg ttctttggtg gccagagaga aggtcttctg ggacctggcg
361 gccacgcgtg cagtctttgg tgttcagagc acagccgcag gcctgtgggc tctgctgggg
421 gaccctgtgc tgcatgccga caaggcgcgt ggccagcaga actggtgctg gtttcacatc
481 acgacagcaa cgggattctt ttgctttgaa aatgttgcag tccacctgtc caacttgatc
541 ttccggacat ttgacttgtt tctggttatc caccatctct ttgcctttct tgggtttctt
601 ggctgcttgg tcaatctcca agctggccac tatctagcta tgaccacgtt gctcctggag
661 atgagcacgc cctttacctg cgtttcctgg atgctcttaa aggcgggctg gtccgagtct
721 ctgttttgga agctcaacca gtggctgatg attcacatgt ttcactgccg catggttcta
781 acctaccaca tgtggtgggt gtgtttctgg cactgggacg gcctggtcag cagcctgtat
841 ctgcctcatt tgacactgtt ccttgtcgga ctggctctgc ttacgctaat cattaatcca
901 tattggaccc ataagaagac tcagcagctt ctcaatccgg tggactggaa cttcgcacag
961 ccagaagcca agagcaggcc agaaggcaac gggcagctgc tgcggaagaa gaggccatag
1021 ctgctccagc cggggctccg gggcggcagc agagctggca caccgattct gggaagcccc
1081 gcgaatgatg gcttttgaat taatgaggca gtgaatgttt tgtgtttact tctaagggaa
1141 atactaactt tctttcgcat tagtattaat tttgaagtag ctacaaagta tttttaagaa
1201 attataattt tatgactgtc tggcaggctc tgtcagttta gccgcgccgg accgtgtcaa
1261 gcatctagga gaggagtcca tggtgtccag gcatcggggc gtcacacctg ttgaggagtg
1321 gggtggcttt gaatgctgga aatggcttca tagtgaagtg cctcccacag ggcgggtggg
1381 tcagcgttga ctctttccag ctgcacactc atatgccgtg tgtcttattc agaagtcaca
1441 ttcttttcag ttggagagaa ttgggctaag atagaaaata acatgatttg ttccttatta
1501 aagtttccca gcgtatgaaa ttctaagctg ggtggggtgg ctcacacccg acgtaatccc
1561 agcacgttgg gaggccgagg caggtggatc acttgaggcc aggagttcga gaccagcctg
1621 gtcaagatgg tgaaacccca tctctactaa aattacaaaa attagccggg tgtcgtggca
1681 cacacctgta atcccagcta tttgggaggc caaggcagga gaattgcctg aacccgggag
1741 gcggaggttg cagtgagctg agatcgcacc actgcactcc agcactccag cctgggtgac
1801 ggagcaagac tctctctcaa aaaaaaaaaa aaaaaaa
//