LOCUS BC007679 3004 bp mRNA linear HUM 01-SEP-2006
DEFINITION Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 7,
mRNA (cDNA clone MGC:3683 IMAGE:3628076), complete cds.
ACCESSION BC007679
VERSION BC007679.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3004)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3004)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007679.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: g Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34335274.
FEATURES Location/Qualifiers
source 1..3004
/db_xref="H-InvDB:HIT000050484"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3683 IMAGE:3628076"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3004
/gene="P2RX7"
/gene_synonym="MGC20089"
/gene_synonym="P2X7"
/db_xref="GeneID:5027"
/db_xref="HGNC:HGNC:8537"
/db_xref="MIM:602566"
CDS 455..1732
/gene="P2RX7"
/gene_synonym="MGC20089"
/gene_synonym="P2X7"
/codon_start=1
/product="P2RX7 protein"
/protein_id="AAH07679.1"
/db_xref="GeneID:5027"
/db_xref="HGNC:HGNC:8537"
/db_xref="MIM:602566"
/translation="MDGPAEQRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNI
TCTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPK
YSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDI
IQLVVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKC
ESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLAL
HDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEALCCRKKPG
ACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQD
MADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY"
BASE COUNT 790 a 779 c 747 g 688 t
ORIGIN
1 gagctctggt ccagctccgc gcagggaggg aggctgtcac catgccggcc tgctgcagct
61 gcagtgatgt tttccagtat gagacgaaca aagtcactcg gatccagagc atgaattatg
121 gcaccattaa gtggttcttc cacgtgatca tcttttccta cgtttgcttt gctctggtga
181 gtgacaagct gtaccagcgg aaagagcctg tcatcagttc tgtgcacacc aaggtgaagg
241 ggatagcaga ggtgaaagag gagatcgtgg agaatggagt gaagaagttg gtgcacagtg
301 tctttgacac cgcagactac accttccctt tgcaggggaa ctctttcttc gtgatgacaa
361 actttctcaa aacagaaggc caagagcagc ggttgtgtcc cgagtatccc acccgcagga
421 cgctctgttc ctctgaccga ggttgtaaaa agggatggat ggacccgcag agcaaaggcc
481 tgctctcttg aacagtgccg aaaacttcac tgtgctcatc aagaacaata tcgacttccc
541 cggccacaac tacaccacga gaaacatcct gccaggttta aacatcactt gtaccttcca
601 caagactcag aatccacagt gtcccatttt ccgactagga gacatcttcc gagaaacagg
661 cgataatttt tcagatgtgg caattcaggg cggaataatg ggcattgaga tctactggga
721 ctgcaaccta gaccgttggt tccatcactg ccgtcccaaa tacagtttcc gtcgccttga
781 cgacaagacc accaacgtgt ccttgtaccc tggctacaac ttcagatacg ccaagtacta
841 caaggaaaac aatgttgaga aacggactct gataaaagtc ttcgggatcc gttttgacat
901 cctggttttt ggcaccggag gaaaatttga cattatccag ctggttgtgt acatcggctc
961 aaccctctcc tacttcggtc tggccgctgt gttcatcgac ttcctcatcg acacttactc
1021 cagtaactgc tgtcgctccc atatttatcc ctggtgcaag tgctgtcagc cctgtgtggt
1081 caacgaatac tactacagga agaagtgcga gtccattgtg gagccaaagc cgacattaaa
1141 gtatgtgtcc tttgtggatg aatcccacat taggatggtg aaccagcagc tactagggag
1201 aagtctgcaa gatgtcaagg gccaagaagt cccaagacct gcgatggact tcacagattt
1261 gtccaggctg cccctggccc tccatgacac acccccgatt cctggacaac cagaggagat
1321 acagctgctt agaaaggagg cgactcctag atccagggat agccccgtct ggtgccagtg
1381 tggaagctgc ctcccatctc aactccctga gagccacagg tgcctggagg cgctgtgctg
1441 ccggaaaaag ccgggggcct gcatcaccac ctcagagctg ttcaggaagc tggtcctgtc
1501 cagacacgtc ctgcagttcc tcctgctcta ccaggagccc ttgctggcgc tggatgtgga
1561 ttccaccaac agccggctgc ggcactgtgc ctacaggtgc tacgccacct ggcgcttcgg
1621 ctcccaggac atggctgact ttgccatcct gcccagctgc tgccgctgga ggatccggaa
1681 agagtttccg aagagtgaag ggcagtacag tggcttcaag agtccttact gaagccaggc
1741 accgtggctc acgtctgtaa tcccagcgct ttgggaggcc gaggcaggca gatcacctga
1801 ggtcgggagt tggagacccg cctggctaac aaggcgaaat cctgtctgta ctaaaaatac
1861 aaaaatcagc cagacatggt ggcatgcacc tgcaatccca gctactcggg aggctgaggc
1921 acaagaatca cttgaacccg ggaggcagag gttgtagtga gcccagattg tgccactgct
1981 ctccagcctg ggaggcacag caaactgtcc ccaaaaaaaa aaaaaagagt ccttaccaat
2041 agcaggggct gcagtagcca tgttaacatg acatttacca gcaacttgaa cttcacctgc
2101 aaagctctgt ggccacattt tcagccaaag ggaaatatgc tttcatcttc tgttgctctc
2161 tgtgtctgag agcaaagtga cctggttaaa caaaccagaa tccctctaca tggactcaga
2221 gaaaagagat tgagatgtaa gtctcaactc tgtccccagg aagttgtgtg accctaggcc
2281 tctcacctct gtgcctctgt ctccttgttg cccaactact atctcagaga tattgtgagg
2341 acaaattgag acagtgcaca tgaactgtct tttaatgtgt aaagatctac atgaatgcaa
2401 aacatttcat tatgaggtca gactaggata atgtccaact aaaaacaaac ccttttcatc
2461 ctggctggag aatgtggaga actaaaggtg gccacaaatt ctttgacact caagtccccc
2521 aagacctaag ggttttatct cctccccttg aatatgggtg gctctgattg ctttatccaa
2581 aagtggaagt gacattgtgt cagtttcaga tcctgatctt aagaggctga cagcttctac
2641 ttgctgtccc ttggaactct tgctatcggg gaagccagac gccatttaaa agtctgccta
2701 tcctggccag gtgtggtggc tcacacctgt aatcccagca ctttgggaga ccaaggcggg
2761 cggatcactt aaagtcagga gtccaagacc agactcgcca acatggtgaa accgtatctc
2821 taataaaaat acaaaaatta gctgggcatg gtgcgggcac ctgtagtcct agctatcaag
2881 aggctgagac aggagaaaca cttgaacctg ggaggtggag gttgcattga gctgagatcg
2941 tgccactgca ctccaggctg ggtgacagag cgagactcca tctcaaaaaa aaaaaaaaaa
3001 aaaa
//