LOCUS BC007670 3442 bp mRNA linear HUM 11-SEP-2007
DEFINITION Homo sapiens minichromosome maintenance complex component 2, mRNA
(cDNA clone MGC:2123 IMAGE:3143264), complete cds.
ACCESSION BC007670
VERSION BC007670.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3442)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3442)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC007670.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: b Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33356546.
FEATURES Location/Qualifiers
source 1..3442
/db_xref="H-InvDB:HIT000033368"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2123 IMAGE:3143264"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3442
/gene="MCM2"
/gene_synonym="BM28"
/gene_synonym="cdc19"
/gene_synonym="D3S3194"
/gene_synonym="MITOTIN"
/db_xref="GeneID:4171"
/db_xref="HGNC:HGNC:6944"
/db_xref="MIM:116945"
CDS 49..2763
/gene="MCM2"
/gene_synonym="BM28"
/gene_synonym="cdc19"
/gene_synonym="D3S3194"
/gene_synonym="MITOTIN"
/codon_start=1
/product="minichromosome maintenance complex component 2"
/protein_id="AAH07670.2"
/db_xref="GeneID:4171"
/db_xref="HGNC:HGNC:6944"
/db_xref="MIM:116945"
/translation="MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGR
DLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDV
EELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATED
GEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKER
ISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDR
ITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNF
VLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPR
SKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNK
VAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG
GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVS
REWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARC
TVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGS
HVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQ
DKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM
LESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQVTYQRNRFGAQQD
TIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQF"
BASE COUNT 764 a 944 c 1021 g 713 t
ORIGIN
1 gcgaaacctg gttgttgctg tagtggcgga gaggatcgtg gtactgctat ggcggaatca
61 tcggaatcct tcaccatggc atccagcccg gcccagcgtc ggcgaggcaa tgatcctctc
121 acctccagcc ctggccgaag ctcccggcgt actgatgccc tcacctccag ccctggccgt
181 gaccttccac catttgagga tgagtccgag gggctcctag gcacagaggg gcccctggag
241 gaagaagagg atggagagga gctcattgga gatggcatgg aaagggacta ccgcgccatc
301 ccagagctgg acgcctatga ggccgaggga ctggctctgg atgatgagga cgtagaggag
361 ctgacggcca gtcagaggga ggcagcagag cgggccatgc ggcagcgtga ccgggaggct
421 ggccggggcc tgggccgcat gcgccgtggg ctcctgtatg acagcgatga ggaggacgag
481 gagcgccctg cccgcaagcg ccgccaggtg gagcgggcca cggaggacgg cgaggaggac
541 gaggagatga ttgagagcat cgagaacctg gaggatctca aaggccactc tgtgcgcgag
601 tgggtgagca tggcgggccc ccggctggag atccaccacc gcttcaagaa cttcctgcgc
661 actcacgtcg acagccacgg ccacaacgtc ttcaaggagc gcatcagcga catgtgcaaa
721 gagaaccgtg agagcctggt ggtgaactat gaggacttgg cagccaggga gcacgtgctg
781 gcctacttcc tgcctgaggc accggcggag ctgctgcaga tctttgatga ggctgccctg
841 gaggtggtac tggccatgta ccccaagtac gaccgcatca ccaaccacat ccatgtccgc
901 atctcccacc tgcctctggt ggaggagctg cgctcgctga ggcagctgca tctgaaccag
961 ctgatccgca ccagtggggt ggtgaccagc tgcactggcg tcctgcccca gctcagcatg
1021 gtcaagtaca actgcaacaa gtgcaatttc gtcctgggtc ctttctgcca gtcccagaac
1081 caggaggtga aaccaggctc ctgtcctgag tgccagtcgg ccggcccctt tgaggtcaac
1141 atggaggaga ccatctatca gaactaccag cgtatccgaa tccaggagag tccaggcaaa
1201 gtggcggctg gccggctgcc ccgctccaag gacgccattc tcctcgcaga tctggtggac
1261 agctgcaagc caggagacga gatagagctg actggcatct atcacaacaa ctatgatggc
1321 tccctcaaca ctgccaatgg cttccctgtc tttgccactg tcatcctagc caaccacgtg
1381 gccaagaagg acaacaaggt tgctgtaggg gaactgaccg atgaagatgt gaagatgatc
1441 actagcctct ccaaggatca gcagatcgga gagaagatct ttgccagcat tgctccttcc
1501 atctatggtc atgaagacat caagagaggc ctggctctgg ccctgttcgg aggggagccc
1561 aaaaacccag gtggcaagca caaggtacgt ggtgatatca acgtgctctt gtgcggagac
1621 cctggcacag cgaagtcgca gtttctcaag tatattgaga aagtgtccag ccgagccatc
1681 ttcaccactg gccagggggc gtcggctgtg ggcctcacgg cgtatgtcca gcggcaccct
1741 gtcagcaggg agtggacctt ggaggctggg gccctggttc tggctgaccg aggagtgtgt
1801 ctcattgatg aatttgacaa gatgaatgac caggacagaa ccagcatcca tgaggccatg
1861 gagcaacaga gcatctccat ctcgaaggct ggcatcgtca cctccctgca ggctcgctgc
1921 acggtcattg ctgccgccaa ccccatagga gggcgctacg acccctcgct gactttctct
1981 gagaacgtgg acctcacaga gcccatcatc tcacgctttg acatcctgtg tgtggtgagg
2041 gacaccgtgg acccagtcca ggacgagatg ctggcccgct tcgtggtggg cagccacgtc
2101 agacaccacc ccagcaacaa ggaggaggag gggctggcca atggcagcgc tgctgagccc
2161 gccatgccca acacgtatgg cgtggagccc ctgccccagg aggtcctgaa gaagtacatc
2221 atctacgcca aggagagggt ccacccgaag ctcaaccaga tggaccagga caaggtggcc
2281 aagatgtaca gtgacctgag gaaagaatct atggcgacag gcagcatccc cattacggtg
2341 cggcacatcg agtccatgat ccgcatggcg gaggcccacg cgcgcatcca tctgcgggac
2401 tatgtgatcg aagacgacgt caacatggcc atccgcgtga tgctggagag cttcatagac
2461 acacagaagt tcagcgtcat gcgcagcatg cgcaagactt ttgcccgcta cctttcattc
2521 cggcgtgaca acaatgagct gttgctcttc atactgaagc agttagtggc agagcaggtg
2581 acatatcagc gcaaccgctt tggggcccag caggacacta ttgaggtccc tgagaaggac
2641 ttggtggata aggctcgtca gatcaacatc cacaacctct ctgcatttta tgacagtgag
2701 ctcttcagga tgaacaagtt cagccacgac ctgaaaagga aaatgatcct gcagcagttc
2761 tgaggcccta tgccatccat aaggattcct tgggattctg gtttggggtg gtcagtgccc
2821 tctgtgcttt atggacacaa aaccagagca cttgatgaac tcggggtact agggtcaggg
2881 cttatagcag gatgtctggc tgcacctggc atgactgttt gtttctccaa gcctgctttg
2941 tgcttctcac ctttgggtgg gatgccttgc cagtgtgtct tacttggttg ctgaacatct
3001 tgccacctcc gagtgctttg tctccactca gtaccttgga tcagagctgc tgagttcagg
3061 atgcctgcgt gtggtttagg tgttagcctt cttacatgga tgtcaggaga gctgctgccc
3121 tcttggcgtg agttgcgtat tcaggctgct tttgctgcct ttggccagag agctggttga
3181 agatgtttgt aatcgttttc agtctcctgc aggtttctgt gcccctgtgg tggaagaggg
3241 cacgacagtg ccagcgcagc gttctgggct cctcagtcgc aggggtggga tgtgagtcat
3301 gcggattatc cactcgccac agttatcagc tgccattgct ccctgtctgt ttccccactc
3361 tcttatttgt gcattcggtt tggtttctgt agttttaatt tttaataaag ttgaataaaa
3421 tataaaaaaa aaaaaaaaaa aa
//