LOCUS BC007621 2155 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens orthodenticle homeobox 1, mRNA (cDNA clone MGC:15736
IMAGE:3355563), complete cds.
ACCESSION BC007621
VERSION BC007621.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2155)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2155)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: p Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27436930.
FEATURES Location/Qualifiers
source 1..2155
/db_xref="H-InvDB:HIT000033337"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15736 IMAGE:3355563"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2155
/gene="OTX1"
/db_xref="GeneID:5013"
/db_xref="HGNC:HGNC:8521"
/db_xref="MIM:600036"
CDS 221..1285
/gene="OTX1"
/codon_start=1
/product="orthodenticle homeobox 1"
/protein_id="AAH07621.1"
/db_xref="GeneID:5013"
/db_xref="HGNC:HGNC:8521"
/db_xref="MIM:600036"
/translation="MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTT
FTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSG
TKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGN
PVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAA
ASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHH
HHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLN
FNSPDCLDYKDQASWRFQVL"
BASE COUNT 433 a 755 c 545 g 422 t
ORIGIN
1 atcacctaaa caaccgagca agacaagcca ctccgacaag gttggctgcc cggcgggtct
61 ctgtgagaga tccaggtaga tggtgaacgg ccccggcagc tgagggcagg ccaggccccc
121 agacgcatca gaccctgaag gactgcgtgg tgggagccct gcaccgctcc tggccccggg
181 ccccctggat ccgtcggggc gcctccaccc agctgttagc atgatgtctt acctcaaaca
241 acccccatac ggcatgaacg ggctgggcct ggccgggccc gccatggacc tcctgcaccc
301 atccgtgggc tatccggcca ctccgcggaa gcagcggcgg gagcgcacca ccttcacgcg
361 ttcacagctg gacgtgctcg aggcgctctt cgccaagact cgctaccctg acatcttcat
421 gcgggaggag gtggcgctca agatcaacct gccggagtct agagtccagg tctggttcaa
481 gaaccgccgc gccaaatgcc gccagcagca gcagagcggg agcggaacca agagccgccc
541 agccaagaag aagtcctctc cagtgcggga gagctcgggc tccgaaagca gtggccaatt
601 cacgccgcca gctgtgtcca gctctgcctc gtcctctagc tcggcgtcca gctcttccgc
661 caacccagcg gctgcagcgg ctgcgggact aggtgggaac ccggtggcgg ccgcgtcgtc
721 gctgagtaca ccagctgcct catctatctg gagcccggcc tccatctcgc caggctcagc
781 gcccgcgtcc gtgtcggtgc cggagccatt ggccgcgcct agcaacacct cgtgtatgca
841 gcgctccgta gctgcaggcg ccgccaccgc agcagcctct tatcccatgt cctacggcca
901 gggcggcagc tacggccaag gctaccctac gccctcctct tcctactttg gcggcgtgga
961 ctgcagctca tacctagcgc ccatgcactc acatcaccac ccgcaccagc tgagccccat
1021 ggcaccctcc tccatggcgg gccaccatca tcaccaccca catgcgcacc acccgttgag
1081 ccagtcctca ggccaccacc accaccatca ccaccaccac caccaaggct acggtggctc
1141 tgggcttgcc ttcaactctg ccgactgctt ggattacaag gagcctggcg ccgctgctgc
1201 ttcctccgcc tggaaactca acttcaactc ccccgactgt ctggactata aggaccaagc
1261 ctcatggcgg ttccaggtct tgtgagccca ggaatgaaag aggagaagaa acgcaactac
1321 ctgcgccctc cgtggtcccg atcctgttgc tgctgctgca ccgcccgcct ttgcctcgtc
1381 ttctccaaaa ctgaattttc accccccaaa aagatgtcca ttgcctgcac tgccgccccc
1441 atttttgtgc cacttgcttg gggggatgtg caaacccacc ctgccccttg gatgggggga
1501 ccggtgcttc ggcttggcct acacattcta tacaggagag atgtattatt tccccccttc
1561 agcccctact aaactcttaa gcctcccctt ccagtctttc tggacagcta ttaagcactt
1621 gcagccttcg gaggctctgc gctctgatcc gctgtttgag cccaacactt taatttattc
1681 tttctggaca ctggagtcac taactggcgt gtttctgccc attggagcac ccgcacacta
1741 ctccaaatca aaaccactaa gagttcctcc cgcgcagact gctgcccctt cagctgccct
1801 cgattttgct ccacgcctgc cggccagagc ctcccggcgt ttcttccgcc ccagcggagt
1861 gcgctggggc gcgccagggc taggcccgcc ggaggagcgc gtccccagcc ttccgcgcac
1921 agagccgcat cccgccccgc cctgcgctgg actggttcaa gcttccgcct cggcgggaac
1981 gctgtacata gtcaggtccg ttccagggac cacttaaact ttttagttgc tgttggttgg
2041 ttgaactgaa catatcttgt cttagcaccc aggaaacaga actttaagat atatacagca
2101 catatatata tatatacata tatatataca catatataaa aaaaaaaaaa aaaaa
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