LOCUS BC007511 1702 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens uridine monophosphate synthetase, mRNA (cDNA clone
MGC:4244 IMAGE:2964556), complete cds.
ACCESSION BC007511
VERSION BC007511.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1702)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1702)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC007511.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 10 Row: p Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507834.
FEATURES Location/Qualifiers
source 1..1702
/db_xref="H-InvDB:HIT000033265"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4244 IMAGE:2964556"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1702
/gene="UMPS"
/gene_synonym="OPRT"
/db_xref="GeneID:7372"
/db_xref="HGNC:HGNC:12563"
/db_xref="MIM:258900"
CDS 24..1466
/gene="UMPS"
/gene_synonym="OPRT"
/codon_start=1
/product="uridine monophosphate synthetase"
/protein_id="AAH07511.1"
/db_xref="GeneID:7372"
/db_xref="HGNC:HGNC:12563"
/db_xref="MIM:258900"
/translation="MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIV
SRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKD
YGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGK
DKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSI
KEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPS
ICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIA
SWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEE
HSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVG
RGIISAADRLEAAEMYRKAAWEAYLSRLGV"
BASE COUNT 470 a 331 c 446 g 455 t
ORIGIN
1 aagcaaacag gcagcgcgcg acaatggcgg tcgctcgtgc agctttgggg ccattggtga
61 cgggtctgta cgacgtgcag gctttcaagt ttggggactt cgtgctgaag agcgggcttt
121 cctcccccat ctacatcgat ctgcggggca tcgtgtctcg accgcgtctt ctgagtcagg
181 ttgcagatat tttattccaa actgcccaaa atgcaggcat cagttttgac accgtgtgtg
241 gagtgcctta tacagctttg ccattggcta cagttatctg ttcaaccaat caaattccaa
301 tgcttattag aaggaaagaa acaaaggatt atggaactaa gcgtcttgta gaaggaacta
361 ttaatccagg agaaacctgt ttaatcattg aagatgttgt caccagtgga tctagtgttt
421 tggaaactgt tgaggttctt cagaaggagg gcttgaaggt cactgatgcc atagtgctgt
481 tggacagaga gcagggaggc aaggacaagt tgcaggcgca cgggatccgc ctccactcag
541 tgtgtacatt gtccaaaatg ctggagattc tcgagcagca gaaaaaagtt gatgctgaga
601 cagttgggag agtgaagagg tttattcagg agaatgtctt tgtggcagcg aatcataatg
661 gttctcccct ttctataaag gaagcaccca aagaactcag cttcggtgca cgtgcagagc
721 tgcccaggat ccacccagtt gcatcgaagc ttctcaggct tatgcaaaag aaggagacca
781 atctgtgtct atctgctgat gtttcactgg ccagagagct gttgcagcta gcagatgctt
841 taggacctag tatctgcatg ctgaagactc atgtagatat tttgaatgat tttactctgg
901 atgtgatgaa ggagttgata actctggcaa aatgccatga gttcttgata tttgaagacc
961 ggaagtttgc agatatagga aacacagtga aaaagcagta tgaaggaggt atctttaaaa
1021 tagcttcctg ggcagatcta gtaaatgctc acgtggtgcc aggctcagga gttgtgaaag
1081 gcctgcaaga agtgggcctg cctttgcatc gggggtgcct ccttattgcg gaaatgagct
1141 ccaccggctc cctggccact ggggactaca ctagagcagc ggttagaatg gctgaggagc
1201 actctgaatt tgttgttggt tttatttctg gctcccgagt aagcatgaaa ccagaatttc
1261 ttcacttgac tccaggagtt cagttggaag caggaggaga taatcttggc caacagtaca
1321 atagcccaca agaagttatt ggcaaacgag gttccgatat catcattgta ggtcgtggca
1381 taatctcagc agctgatcgt ctggaagcag cagagatgta cagaaaagct gcttgggaag
1441 cgtatttgag tagacttggt gtttgagtgc ttcagataca tttttcagat acaatgtgaa
1501 gacattgaag atatgtggtc ctcctgaaag tcactggctg gaaataatcc aattattcct
1561 gcttggattc ttccacaggg cctgtgtaag aatgggttct ggagttctca tggtctttag
1621 gaaatattga gtaatttgta atcaccgcat tgatactata ataagttcat tcttaagctt
1681 gaaaaaaaaa aaaaaaaaaa aa
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