LOCUS       BC007456                1880 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens GDP-mannose pyrophosphorylase A, mRNA (cDNA clone
            MGC:995 IMAGE:2989461), complete cds.
ACCESSION   BC007456
VERSION     BC007456.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1880)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-MAY-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 19, 2003 this sequence version replaced BC007456.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 3 Row: k Column: 14
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 45447089.
FEATURES             Location/Qualifiers
     source          1..1880
                     /db_xref="H-InvDB:HIT000033237"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:995 IMAGE:2989461"
                     /tissue_type="Lymph, Burkitt lymphoma"
                     /clone_lib="NIH_MGC_8"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..1880
                     /gene="GMPPA"
                     /db_xref="GeneID:29926"
                     /db_xref="HGNC:HGNC:22923"
     CDS             364..1626
                     /gene="GMPPA"
                     /codon_start=1
                     /product="GDP-mannose pyrophosphorylase A"
                     /protein_id="AAH07456.1"
                     /db_xref="GeneID:29926"
                     /db_xref="HGNC:HGNC:22923"
                     /translation="MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEAC
                     AQVPGMQEILLIGFYQPDEPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQI
                     LAGSPEAFFVLNADVCSDFPLSAMLEAHRRQRHPFLLLGTTANRTQSLNYGCIVENPQ
                     THEVLHYVEKPSTFISDIINCGIYLFSPEALKPLRDVFQRNQQDGQLEDSPGLWPGAG
                     TIRLEQDVFSALAGQGQIYVHLTDGIWSQIKSAGSALYASRLYLSRYQDTHPERLAKH
                     TPGGPWIRGNVYIHPTAKVAPSAVLGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHT
                     CVLHSIVGWGSTVGRWARVEGTPSDPNPNDPRARMDSESLFKDGKLLPAITILGCRVR
                     IPAEVLILNSIVLPHKELSRSFTNQIIL"
BASE COUNT          440 a          531 c          527 g          382 t
ORIGIN      
        1 gggcggcaga gctggagtga agggagctag tggtaaaggg agctggtgga ggggtggcgg
       61 caggggtaag gggcagggga caccctctag acggagagcg ggctccgagg tcctggctgg
      121 ccctcggtgc gcccgcccct gtgttggtcc cacaatccct ggcaatgaga ggccagggtt
      181 tattggacag agtcagttgt ggggttcaga gggtcagcaa tcaatcaatc ctccgaatcc
      241 agagatttag acccagtcgt ccgtattagg actggagggg ggtcaatagg ttcagtgttt
      301 gagatgccaa gggaacctgt cttttgattt ggggttcaac atacagaggt agcagtcacc
      361 attatgctca aagcggtgat cctgattgga ggccctcaaa agggaactcg cttcagacct
      421 ttgtcttttg aggtgcccaa accattgttt cctgtggcag gggtccctat gatccaacac
      481 catattgaag cctgtgccca ggtccctgga atgcaggaga ttctgctcat tggcttctac
      541 caacctgatg agcccctcac ccagttccta gaagccgccc agcaggagtt taaccttcca
      601 gtcaggtacc tgcaggaatt tgccccccta ggcacagggg gtggtcttta ccattttcga
      661 gaccagatcc tggctgggag ccccgaggca ttcttcgtgc tcaatgctga tgtctgctcc
      721 gacttcccct tgagtgctat gttggaagcc caccgacgcc agcgtcaccc tttcttactc
      781 cttggcacta cggctaacag gacgcaatcc ctcaactacg gctgcatcgt tgagaatcca
      841 cagacacacg aggtattgca ctatgtggag aaacccagca catttatcag tgacatcatc
      901 aactgcggca tctacctctt ttctcctgaa gccttgaagc ctcttcggga tgtcttccag
      961 cgtaatcagc aggatgggca attggaggac tcaccaggct tgtggccagg ggcaggtacc
     1021 atccgcctag agcaggatgt gttttcagcc ctggcagggc agggccagat atacgtgcat
     1081 ctcactgatg gtatctggag tcagatcaag tccgcaggtt cagccctcta cgcctcccgc
     1141 ctctacctga gccgatacca ggacactcac ccagaacggc tggccaagca caccccaggg
     1201 ggcccatgga tccgagggaa tgtgtacatc cacccgaccg ccaaggtggc cccctcggct
     1261 gtgctgggcc ccaacgtctc catcgggaag ggggtgaccg tgggtgaggg tgtgcggctc
     1321 cgggagagca tcgtcctcca tggagccact ttgcaggagc acacgtgtgt tctgcatagc
     1381 atcgtgggct gggggagcac cgtgggacgc tgggcccgcg tggagggtac ccccagtgac
     1441 cctaacccca acgatccccg agcccgcatg gacagtgaga gcctcttcaa ggacgggaag
     1501 ctgctgcctg ctatcaccat cctgggctgc cgagtccgga tccctgccga ggtgctcatc
     1561 ctgaactcga ttgttctgcc acacaaggag ctgagccgaa gcttcaccaa ccagatcatc
     1621 ctctgagtag ggctgccaga aggcccccag ctcctaccca ctccccttga ggctgctgcc
     1681 tgcttggcca gcctctgtcc agaaaggacc agagaaagcc aggctggatc gtcacatgcc
     1741 ggggagcaat gtggatggcc tggggactcc tgggttttct ccctcccgac tccctaataa
     1801 accccgtgaa ccttggaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1861 aaaaaaaaaa aaaaaaaaaa
//