LOCUS BC007390 1299 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens tripartite motif-containing 28, mRNA (cDNA clone
IMAGE:3831930), partial cds.
ACCESSION BC007390
VERSION BC007390.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1299)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1299)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007390.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 24 Row: f Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1299
/db_xref="H-InvDB:HIT000086816"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3831930"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1299
/gene="TRIM28"
/gene_synonym="KAP1"
/gene_synonym="RNF96"
/gene_synonym="TF1B"
/gene_synonym="TIF1B"
/db_xref="GeneID:10155"
/db_xref="MIM:601742"
CDS <1..1114
/gene="TRIM28"
/gene_synonym="KAP1"
/gene_synonym="RNF96"
/gene_synonym="TF1B"
/gene_synonym="TIF1B"
/codon_start=2
/product="TRIM28 protein"
/protein_id="AAH07390.2"
/db_xref="GeneID:10155"
/db_xref="MIM:601742"
/translation="SGVKRSRSGEGEVSGLMRKVPRVSLERLDLDLTADSQPPVFKVF
PGSTTEDYNLIVIERGAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPT
ATEGPETKPVLMALAEGPGAEGPRLASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSA
TICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLS
LDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPGGTLDLT
LIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEA
FGDTKFSAVLVEPPPMSLPGAGLSSQELSGGPGDGP"
misc_feature 485..619
/gene="TRIM28"
/gene_synonym="KAP1"
/gene_synonym="RNF96"
/gene_synonym="TF1B"
/gene_synonym="TIF1B"
/note="PHD; Region: PHD-finger. PHD folds into an
interleaved type of Zn-finger chelating 2 Zn ions in a
similar manner to that of the RING and FYVE domains"
/db_xref="CDD:pfam00628"
misc_feature 695..1009
/gene="TRIM28"
/gene_synonym="KAP1"
/gene_synonym="RNF96"
/gene_synonym="TF1B"
/gene_synonym="TIF1B"
/note="BROMO; Region: bromo domain"
/db_xref="CDD:smart00297"
BASE COUNT 249 a 414 c 372 g 264 t
ORIGIN
1 gtcaggtgtg aaacggtccc gctcaggtga gggcgaggtg agcggcctta tgcgcaaggt
61 gccacgagtg agccttgaac gcctggacct ggacctcaca gctgacagcc agccacccgt
121 cttcaaggtc ttcccaggca gtaccactga ggactacaac cttattgtta ttgaacgtgg
181 cgctgccgct gcagctaccg gccagccagg gactgcgcct gcaggaaccc ctggtgcccc
241 acccctggct ggcatggcca ttgtcaagga ggaggagacg gaggctgcca ttggagcccc
301 tcctactgcc actgagggcc ctgagaccaa acctgtgctt atggctcttg cggagggtcc
361 tggtgctgag ggtccccgcc tggcctcacc tagtggcagc accagctcag ggctggaggt
421 ggtggctcct gagggtacct cagccccagg tggtggcccg ggaaccctgg atgacagtgc
481 caccatttgc cgtgtctgcc agaagccagg cgatctggtt atgtgcaacc agtgtgagtt
541 ttgtttccac ctggactgtc acctgccggc cctgcaggat gtaccagggg aggagtggag
601 ctgctcactc tgccatgtgc tccctgacct gaaggaggag gatggcagcc tcagcctgga
661 tggtgcagac agcactggcg tggtggccaa gctctcacca gccaaccagc ggaaatgtga
721 gcgtgtactg ctggccctat tctgtcacga accctgccgc cccctgcatc agctggctac
781 cgactccacc ttctccctgg accagcccgg tggcaccctg gatctgaccc tgatccgtgc
841 ccgcctccag gagaagttgt cacctcccta cagctcccca caggagtttg cccaggatgt
901 gggccgcatg ttcaagcaat tcaacaagtt aactgaggac aaggcagacg tgcagtccat
961 catcggcctg cagcgcttct tcgagacgcg catgaacgag gccttcggtg acaccaagtt
1021 ctctgctgtg ctggtggagc ccccgccgat gagcctgcct ggtgctggcc tgagttccca
1081 ggagctgtct ggtggccctg gtgatggccc ctgaggctgg agcccccatg gccagcccag
1141 cctggctctg ttctctgtcc tgtcacccca tccccactcc cctggtggcc tgactcccac
1201 tccctggtgg ccccatcccc cagttcctca cgatatggtt tttacttctg tggatttaat
1261 aaaaacttca ccagttaaaa aaaaaaaaaa aaaaaaaaa
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