LOCUS BC007231 2544 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens plasminogen activator, tissue, mRNA (cDNA clone
MGC:15287 IMAGE:3161005), complete cds.
ACCESSION BC007231
VERSION BC007231.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2544)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2544)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: i Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14702165.
FEATURES Location/Qualifiers
source 1..2544
/db_xref="H-InvDB:HIT000033086"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15287 IMAGE:3161005"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2544
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
CDS 82..1770
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/codon_start=1
/product="plasminogen activator, tissue"
/protein_id="AAH07231.1"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
/translation="MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDE
KTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALY
FSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKP
YSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFG
NGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKP
WCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRR
SPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKY
IVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYG
KHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDA
CQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP"
BASE COUNT 633 a 685 c 684 g 542 t
ORIGIN
1 ggagtccagg gctggagaga aaacctctgc gaggaaaggg aaggagcaag ccgtgaattt
61 aagggacgct gtgaagcaat catggatgca atgaagagag ggctctgctg tgtgctgctg
121 ctgtgtggag cagtcttcgt ttcgcccagc caggaaatcc atgcccgatt cagaagagga
181 gccagatctt accaagtgat ctgcagagat gaaaaaacgc agatgatata ccagcaacat
241 cagtcatggc tgcgccctgt gctcagaagc aaccgggtgg aatattgctg gtgcaacagt
301 ggcagggcac agtgccactc agtgcctgtc aaaagttgca gcgagccaag gtgtttcaac
361 gggggcacct gccagcaggc cctgtacttc tcagatttcg tgtgccagtg ccccgaagga
421 tttgctggga agtgctgtga aatagatacc agggccacgt gctacgagga ccagggcatc
481 agctacaggg gcacgtggag cacagcggag agtggcgccg agtgcaccaa ctggaacagc
541 agcgcgttgg cccagaagcc ctacagcggg cggaggccag atgccatcag gctgggcctg
601 gggaaccaca actactgcag aaacccagat cgagactcaa agccctggtg ctacgtcttt
661 aaggcgggga agtacagctc agagttctgc agcacccctg cctgctctga gggaaacagt
721 gactgctact ttgggaatgg gtcagcctac cgtggcacgc acagcctcac cgagtcgggt
781 gcctcctgcc tcccgtggaa ttccatgatc ctgataggca aggtttacac agcacagaac
841 cccagtgccc aggcactggg cctgggcaaa cataattact gccggaatcc tgatggggat
901 gccaagccct ggtgccacgt gctgaagaac cgcaggctga cgtgggagta ctgtgatgtg
961 ccctcctgct ccacctgcgg cctgagacag tacagccagc ctcagtttcg catcaaagga
1021 gggctcttcg ccgacatcgc ctcccacccc tggcaggctg ccatctttgc caagcacagg
1081 aggtcgcccg gagagcggtt cctgtgcggg ggcatactca tcagctcctg ctggattctc
1141 tctgccgccc actgcttcca ggagaggttt ccgccccacc acctgacggt gatcttgggc
1201 agaacatacc gggtggtccc tggcgaggag gagcagaaat ttgaagtcga aaaatacatt
1261 gtccataagg aattcgatga tgacacttac gacaatgaca ttgcgctgct gcagctgaaa
1321 tcggattcgt cccgctgtgc ccaggagagc agcgtggtcc gcactgtgtg ccttcccccg
1381 gcggacctgc agctgccgga ctggacggag tgtgagctct ccggctacgg caagcatgag
1441 gccttgtctc ctttctattc ggagcggctg aaggaggctc atgtcagact gtacccatcc
1501 agccgctgca catcacaaca tttacttaac agaacagtca ccgacaacat gctgtgtgct
1561 ggagacactc ggagcggcgg gccccaggca aacttgcacg acgcctgcca gggcgattcg
1621 ggaggccccc tggtgtgtct gaacgatggc cgcatgactt tggtgggcat catcagctgg
1681 ggcctgggct gtggacagaa ggatgtcccg ggtgtgtaca ccaaggttac caactaccta
1741 gactggattc gtgacaacat gcgaccgtga ccaggaacac ccgactcctc aaaagcaaat
1801 gagatcccgc ctcttcttct tcagaagaca ctgcaaaggc gcagtgcttc tctacagact
1861 tctccagacc caccacaccg cagaagcggg acgagaccct acaggagagg gaagagtgca
1921 ttttcccaga tacttcccat tttggaagtt ttcaggactt ggtctgattt caggatactc
1981 tgtcagatgg gaagacatga atgcacacta gcctctccag gaatgcctcc tccctgggca
2041 gaaagtggcc atgccaccct gttttcagct aaagcccaac ctcctgacct gtcaccgtga
2101 gcagctttgg aaacaggacc acaaaaatga aagcatgtct caatagtaaa agataacaag
2161 atctttcagg aaagacggat tgcattagaa atagacagta tatttatagt cacaagagcc
2221 cagcagggcc tcaaagttgg ggcaggctgg ctggcccgtc atgttcctca aaagcaccct
2281 tgacgtcaag tctccttccc ctttccccac tccctggctc tcagaaggta ttccttttgt
2341 gtacagtgtg taaagtgtaa atcctttttc tttataaact ttagagtagc atgagagaat
2401 tgtatcattt gaacaactag gcttcagcat atttatagca atccatgtta gtttttactt
2461 tctgttgcca caaccctgtt ttatactgta cttaataaat tcagatatat ttttcacagt
2521 ttttccaaaa aaaaaaaaaa aaaa
//