LOCUS BC007024 1290 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol
dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid
dehydrogenase, type III), mRNA (cDNA clone MGC:12374
IMAGE:3681970), complete cds.
ACCESSION BC007024
VERSION BC007024.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1290)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1290)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: a Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56121816.
FEATURES Location/Qualifiers
source 1..1290
/db_xref="H-InvDB:HIT000032994"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12374 IMAGE:3681970"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1290
/gene="AKR1C2"
/gene_synonym="AKR1C-pseudo"
/gene_synonym="BABP"
/gene_synonym="DD"
/gene_synonym="DD2"
/gene_synonym="HAKRD"
/gene_synonym="HBAB"
/gene_synonym="MCDR2"
/db_xref="GeneID:1646"
/db_xref="HGNC:HGNC:385"
/db_xref="MIM:600450"
CDS 23..994
/gene="AKR1C2"
/gene_synonym="AKR1C-pseudo"
/gene_synonym="BABP"
/gene_synonym="DD"
/gene_synonym="DD2"
/gene_synonym="HAKRD"
/gene_synonym="HBAB"
/gene_synonym="MCDR2"
/codon_start=1
/product="aldo-keto reductase family 1, member C2
(dihydrodiol dehydrogenase 2; bile acid binding protein;
3-alpha hydroxysteroid dehydrogenase, type III)"
/protein_id="AAH07024.1"
/db_xref="GeneID:1646"
/db_xref="HGNC:HGNC:385"
/db_xref="MIM:600450"
/translation="MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEA
GFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERS
LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLA
KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSA
LGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQR
IRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY"
BASE COUNT 409 a 276 c 302 g 303 t
ORIGIN
1 gctaaccagg ccagtgacag aaatggattc gaaataccag tgtgtgaagc tgaatgatgg
61 tcacttcatg cctgtcctgg gatttggcac ctatgcgcct gcagaggttc ctaaaagtaa
121 agctctagag gccgtcaaat tggcaataga agccgggttc caccatattg attctgcaca
181 tgtttacaat aatgaggagc aggttggact ggccatccga agcaagattg cagatggcag
241 tgtgaagaga gaagacatat tctacacttc aaagctttgg agcaattccc atcgaccaga
301 gttggtccga ccagccttgg aaaggtcact gaaaaatctt caattggact atgttgacct
361 ctatcttatt cattttccag tgtctgtaaa gccaggtgag gaagtgatcc caaaagatga
421 aaatggaaaa atactatttg acacagtgga tctctgtgcc acatgggagg ccatggagaa
481 gtgtaaagat gcaggattgg ccaagtccat cggggtgtcc aacttcaacc acaggctgct
541 ggagatgatc ctcaacaagc cagggctcaa gtacaagcct gtctgcaacc aggtggaatg
601 tcatccttac ttcaaccaga gaaaactgct ggatttctgc aagtcaaaag acattgttct
661 ggttgcctat agtgctctgg gatcccatcg agaagaacca tgggtggacc cgaactcccc
721 ggtgctcttg gaggacccag tcctttgtgc cttggcaaaa aagcacaagc gaaccccagc
781 cctgattgcc ctgcgctacc agctgcagcg tggggttgtg gtcctggcca agagctacaa
841 tgagcagcgc atcagacaga acgtgcaggt gtttgaattc cagttgactt cagaggagat
901 gaaagccata gatggcctaa acagaaatgt gcgatatttg acccttgata tttttgctgg
961 cccccctaat tatccatttt ctgatgaata ttaacatgga gggcattgca tgaggtctgc
1021 cagaaggccc tgcgtgtgga tggtgacaca gaggatggct ctatgctggt gactggacac
1081 atcgcctctg gttaaatctc tcctgcttgg cgacttcagt aagctacagc taagcccatc
1141 ggccggaaaa gaaagacaat aattttgttt ttcattttga aaaaattaaa tgctctctcc
1201 taaagattct tcacctaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaatt
1261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//