LOCUS BC006233 1589 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ketohexokinase (fructokinase), mRNA (cDNA clone
MGC:10370 IMAGE:3946893), complete cds.
ACCESSION BC006233
VERSION BC006233.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1589)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1589)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC006233.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: b Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557692.
FEATURES Location/Qualifiers
source 1..1589
/db_xref="H-InvDB:HIT000032690"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10370 IMAGE:3946893"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1589
/gene="KHK"
/db_xref="GeneID:3795"
/db_xref="HGNC:HGNC:6315"
/db_xref="MIM:229800"
CDS 456..1352
/gene="KHK"
/codon_start=1
/product="ketohexokinase (fructokinase)"
/protein_id="AAH06233.1"
/db_xref="GeneID:3795"
/db_xref="HGNC:HGNC:6315"
/db_xref="MIM:229800"
/translation="MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNAS
NSCTILSLLGAPCAFMGSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIIN
EASGSRTILYYDRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQ
PPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKG
AVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQE
ALRFGCQVAGKKCGLQGFDGIV"
BASE COUNT 327 a 431 c 517 g 314 t
ORIGIN
1 ctcgcgtgtc ccgggtcggg agtcggagac gcaggtgcag gagagtgcgg ggcaagtagc
61 gcattttctc tttgcattct cgagatcgct tagccgcgct ttaaaaaggt ttgcatcagc
121 tgtgagtcca tctgacaagc gaggaaacta aggctgagaa gtgggaggcg ttgccatctg
181 caggcccagg caacctgcta cgggaagacc ggggaccaag acctctgggt tggctttcct
241 agacccgctc gggtcttcgg gtgtcgcgag gaagggccct gctcctttcg ttccctgcac
301 ccctggccgc tgcaggtggc tccctggagg aggagctccc acgcggagga ggagccaggg
361 cagctgggag cggggacacc atcctcctgg ataagaggca gaggccggga ggaaccccgt
421 cagccgggcg ggcaggaagc tctgggagta gcctcatgga agagaagcag atcctgtgcg
481 tggggctagt ggtgctggac gtcatcagcc tggtggacaa gtaccctaag gaggactcgg
541 agataaggtg tttgtcccag agatggcagc gcggaggcaa cgcgtccaac tcctgcacca
601 ttctctccct gctcggagcc ccctgtgcct tcatgggctc aatggctcct ggccatgttg
661 ctgattttgt cctggatgac ctccgccgtt attctgtgga cctacgctac acagtctttc
721 agaccacagg ctccgtcccc atcgccacgg tcatcatcaa cgaggccagt ggtagccgca
781 ccatcctata ctatgacagg agcctgccag atgtgtctgc tacagacttt gagaaggttg
841 atctgaccca gttcaagtgg atccacattg agggccggaa cgcatcggag caggtgaaga
901 tgctgcagcg gatagacgca cacaacacca ggcagcctcc agagcagaag atccgggtgt
961 ccgtggaggt ggagaagcca cgagaggagc tcttccagct gtttggctac ggagacgtgg
1021 tgtttgtcag caaagatgtg gccaagcact tggggttcca gtcagcagag gaagccttga
1081 ggggcttgta tggtcgtgtg aggaaagggg ctgtgcttgt ctgtgcctgg gctgaggagg
1141 gcgccgacgc cctgggccct gatggcaaat tgctccactc ggatgctttc ccgccacccc
1201 gcgtggtgga tacactggga gctggagaca ccttcaatgc ctccgtcatc ttcagcctct
1261 cccaggggag gagcgtgcag gaagcactga gattcgggtg ccaggtggcc ggcaagaagt
1321 gtggcctgca gggctttgat ggcatcgtgt gagagcaggt gccggctcct cacacaccat
1381 ggagactacc attgcggctg catcgccttc tcccctccat ccagcctggc gtccaggttg
1441 ccctgttcag gggacagatg caagctgtgg ggaggactct gcctgtgtcc tgtgttcccc
1501 acagggagag gctctggggg gatggctggg ggatgcagag cctcagagca aataaatctt
1561 cctcagagcc aaaaaaaaaa aaaaaaaaa
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