LOCUS BC006225 1648 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens transcription factor EB, mRNA (cDNA clone
IMAGE:3944945), partial cds.
ACCESSION BC006225
VERSION BC006225.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1648)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1648)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC006225.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: i Column: 23.
FEATURES Location/Qualifiers
source 1..1648
/db_xref="H-InvDB:HIT000086618"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3944945"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1648
/gene="TFEB"
/gene_synonym="TCFEB"
/db_xref="GeneID:7942"
/db_xref="MIM:600744"
CDS <1..1005
/gene="TFEB"
/gene_synonym="TCFEB"
/codon_start=1
/product="TFEB protein"
/protein_id="AAH06225.2"
/db_xref="GeneID:7942"
/db_xref="MIM:600744"
/translation="HFQSPPPVPGEVLKLDDVIDNIMRLDDVLGYINPEMQMPNTLPL
SSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIE
RRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHS
RRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEAL
MLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLA
PGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL
"
misc_feature 271..453
/gene="TFEB"
/gene_synonym="TCFEB"
/note="HLH; Region: Helix-loop-helix domain, found in
specific DNA- binding proteins that act as transcription
factors"
/db_xref="CDD:cd00083"
BASE COUNT 339 a 524 c 494 g 291 t
ORIGIN
1 cacttccagt cgccaccacc tgtgcctggg gaggtgttga agttggatga tgtcattgac
61 aacattatgc gtctggacga tgtccttggc tacatcaatc ctgaaatgca gatgcccaac
121 acgctacccc tgtccagcag ccacctgaat gtgtacagca gcgaccccca ggtcacagcc
181 tccctggtgg gcgtcaccag cagctcctgc cctgcggacc tgacccagaa gcgagagctc
241 acagatgctg agagcagggc cctggccaag gagcggcaga agaaagacaa tcacaactta
301 attgaaagga gacgaaggtt caacatcaat gaccgcatca aggagttggg aatgctgatc
361 cccaaggcca atgacctgga cgtgcgctgg aacaagggca ccatcctcaa ggcctctgtg
421 gattacatcc ggaggatgca gaaggacctg caaaagtcca gggagctgga gaaccactct
481 cgccgcctgg agatgaccaa caagcagctc tggctccgta tccaggagct ggagatgcag
541 gctcgagtgc acggcctccc taccacctcc ccgtccggca tgaacatggc tgagctggcc
601 cagcaggtgg tgaagcagga gctgcctagc gaagagggcc caggggaggc cctgatgctg
661 ggggctgagg tccctgaccc tgagccactg ccagctctgc ccccgcaagc cccgctgccc
721 ctgcccaccc agccaccgtc cccattccat cacctggact tcagccacag cctgagcttt
781 gggggcaggg aggacgaggg tcccccgggc taccccgaac ccctggcacc ggggcatggc
841 tccccattcc ccagcctgtc caagaaggat ctggacctca tgctcctgga cgactcactg
901 ctaccgctgg cctctgatcc acttctgtcc accatgtccc ccgaggcctc caaggccagc
961 agccgccgga gcagcttcag catggaggag ggcgatgtgc tgtgaccctg gctgcccctg
1021 tgccagggaa caggggccgg cctgggggct gggagggcca ggggcacctc cctcccaccc
1081 ttcaggctgc actgtgtgtg aagtagccac ctgccctgcc tccctcctcc ccgttggccc
1141 ctgtttggac ttagtgcctg tctggcagcc tgtggggtca ggagaagcac ccccagggca
1201 gccctcttga ctggcgcagt gggaagaggc cttcagcccc tctcccggag atggaatcgc
1261 ggggcaggga ggggcagggt gttctagagg tgagaagagg gcctggtgga gattccctgt
1321 cttctgagcc cgagcccctc attaccagtg aaggacatgc ttgaggggtt cgggaagctc
1381 ctcatctgag gcaactggtc ctgggggtgc tcaggcctgc ctttttggga ctcagatggc
1441 aggaggtcca ccccgcagcc tggtcctcgg ctctcccaca ggtgggcacc ccccactttg
1501 gtgctaatag ctctccacca ggtggtgtga gcgcgggggc tgccagaagc gggaggggtc
1561 actgccggaa gagcagctgc cctccgaccc ctcactttgt gcctttagta aacactgtgc
1621 tttgtaaaaa aaaaaaaaaa aaaaaaaa
//