LOCUS BC006124 1663 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens IMP (inosine monophosphate) dehydrogenase 2, mRNA
(cDNA clone MGC:13021 IMAGE:3545693), complete cds.
ACCESSION BC006124
VERSION BC006124.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1663)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1663)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: f Column: 15.
FEATURES Location/Qualifiers
source 1..1663
/db_xref="H-InvDB:HIT000032622"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13021 IMAGE:3545693"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1663
/gene="IMPDH2"
/gene_synonym="IMPD2"
/gene_synonym="IMPDH-II"
/db_xref="GeneID:3615"
/db_xref="HGNC:HGNC:6053"
/db_xref="MIM:146691"
CDS 41..1585
/gene="IMPDH2"
/gene_synonym="IMPD2"
/gene_synonym="IMPDH-II"
/codon_start=1
/product="IMP (inosine monophosphate) dehydrogenase 2"
/protein_id="AAH06124.1"
/db_xref="GeneID:3615"
/db_xref="HGNC:HGNC:6053"
/db_xref="MIM:146691"
/translation="MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDF
TADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQAN
EVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISS
RDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDEL
VAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSS
QGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQ
EVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAA
TTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHS
YEKRLF"
BASE COUNT 436 a 412 c 448 g 367 t
ORIGIN
1 cgcggtcctc ggagacacgc ggcggtgtcc tgtgttggcc atggccgact acctgattag
61 tgggggcacg tcctacgtgc cagacgacgg actcacagca cagcagctct tcaactgcgg
121 agacggcctc acctacaatg actttctcat tctccctggg tacatcgact tcactgcaga
181 ccaggtggac ctgacttctg ctctgaccaa gaaaatcact cttaagaccc cactggtttc
241 ctctcccatg gacacagtca cagaggctgg gatggccata gcaatggcgc ttacaggcgg
301 tattggcttc atccaccaca actgtacacc tgaattccag gccaatgaag ttcggaaagt
361 gaagaaatat gaacagggat tcatcacaga ccctgtggtc ctcagcccca aggatcgcgt
421 gcgggatgtt tttgaggcca aggcccggca tggtttctgc ggtatcccaa tcacagacac
481 aggccggatg gggagccgct tggtgggcat catctcctcc agggacattg attttctcaa
541 agaggaggaa catgactgtt tcttggaaga gataatgaca aagagggaag acttggtggt
601 agcccctgca ggcatcacac tgaaggaggc aaatgaaatt ctgcagcgca gcaagaaggg
661 aaagttgccc attgtaaatg aagatgatga gcttgtggcc atcattgccc ggacagacct
721 gaagaagaat cgggactacc cactagcctc caaagatgcc aagaaacagc tgctgtgtgg
781 ggcagccatt ggcactcatg aggatgacaa gtataggctg gacttgctcg cccaggctgg
841 tgtggatgta gtggttttgg actcttccca gggaaattcc atcttccaga tcaatatgat
901 caagtacatc aaagacaaat accctaatct ccaagtcatt ggaggcaatg tggtcactgc
961 tgcccaggcc aagaacctca ttgatgcagg tgtggatgcc ctgcgggtgg gcatgggaag
1021 tggctccatc tgcattacgc aggaagtgct ggcctgtggg cggccccaag caacagcagt
1081 gtacaaggtg tcagagtatg cacggcgctt tggtgttccg gtcattgctg atggaggaat
1141 ccaaaatgtg ggtcatattg cgaaagcctt ggcccttggg gcctccacag tcatgatggg
1201 ctctctcctg gctgccacca ctgaggcccc tggtgaatac ttcttttccg atgggatccg
1261 gctaaagaaa tatcgcggta tgggttctct cgatgccatg gacaagcacc tcagcagcca
1321 gaacagatat ttcagtgaag ctgacaaaat caaagtggcc cagggagtgt ctggtgctgt
1381 gcaggacaaa gggtcaatcc acaaatttgt cccttacctg attgctggca tccaacactc
1441 atgccaggac attggtgcca agagcttgac ccaagtccga gccatgatgt actctgggga
1501 gcttaagttt gagaagagaa cgtcctcagc ccaggtggaa ggtggcgtcc atagcctcca
1561 ttcgtatgag aagcggcttt tctgaaaagg gatccagcac acctcctcgg tttttttttc
1621 aataaaagtt tagaaagaaa aaaaaaaaaa aaaaaaaaaa aaa
//