LOCUS BC006093 2373 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa
gelatinase, 92kDa type IV collagenase), mRNA (cDNA clone MGC:12688
IMAGE:4054882), complete cds.
ACCESSION BC006093
VERSION BC006093.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2373)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2373)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: p Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4826835.
FEATURES Location/Qualifiers
source 1..2373
/db_xref="H-InvDB:HIT000032598"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12688 IMAGE:4054882"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2373
/gene="MMP9"
/gene_synonym="GELB"
/db_xref="GeneID:4318"
/db_xref="HGNC:HGNC:7176"
/db_xref="MIM:120361"
CDS 6..2129
/gene="MMP9"
/gene_synonym="GELB"
/codon_start=1
/product="matrix metallopeptidase 9 (gelatinase B, 92kDa
gelatinase, 92kDa type IV collagenase)"
/protein_id="AAH06093.1"
/db_xref="GeneID:4318"
/db_xref="HGNC:HGNC:7176"
/db_xref="MIM:120361"
/translation="MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQL
AEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVP
DLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY
SRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVV
PTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERL
YTRDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRAD
STVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQG
YSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYGPRPEPE
PRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPTGPPTAGPSTATTVP
LSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRK
LDSVFEEPLSKKLFFFSGRQVWVYTGASVLGPRRLDKLGLGADVAQVTGALRSGRGKM
LLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYREKAYFCQDRFYWRV
SSRSELNQVDQVGYVTYDILQCPED"
BASE COUNT 461 a 753 c 696 g 463 t
ORIGIN
1 tcaccatgag cctctggcag cccctggtcc tggtgctcct ggtgctgggc tgctgctttg
61 ctgcccccag acagcgccag tccacccttg tgctcttccc tggagacctg agaaccaatc
121 tcaccgacag gcagctggca gaggaatacc tgtaccgcta tggttacact cgggtggcag
181 agatgcgtgg agagtcgaaa tctctggggc ctgcgctgct gcttctccag aagcaactgt
241 ccctgcccga gaccggtgag ctggatagcg ccacgctgaa ggccatgcga accccacggt
301 gcggggtccc agacctgggc agattccaaa cctttgaggg cgacctcaag tggcaccacc
361 acaacatcac ctattggatc caaaactact cggaagactt gccgcgggcg gtgattgacg
421 acgcctttgc ccgcgccttc gcactgtgga gcgcggtgac gccgctcacc ttcactcgcg
481 tgtacagccg ggacgcagac atcgtcatcc agtttggtgt cgcggagcac ggagacgggt
541 atcccttcga cgggaaggac gggctcctgg cacacgcctt tcctcctggc cccggcattc
601 agggagacgc ccatttcgac gatgacgagt tgtggtccct gggcaagggc gtcgtggttc
661 caactcggtt tggaaacgca gatggcgcgg cctgccactt ccccttcatc ttcgagggcc
721 gctcctactc tgcctgcacc accgacggtc gctccgacgg cttgccctgg tgcagtacca
781 cggccaacta cgacaccgac gaccggtttg gcttctgccc cagcgagaga ctctacaccc
841 gggacggcaa tgctgatggg aaaccctgcc agtttccatt catcttccaa ggccaatcct
901 actccgcctg caccacggac ggtcgctccg acggctaccg ctggtgcgcc accaccgcca
961 actacgaccg ggacaagctc ttcggcttct gcccgacccg agctgactcg acggtgatgg
1021 ggggcaactc ggcgggggag ctgtgcgtct tccccttcac tttcctgggt aaggagtact
1081 cgacctgtac cagcgagggc cgcggagatg ggcgcctctg gtgcgctacc acctcgaact
1141 ttgacagcga caagaagtgg ggcttctgcc cggaccaagg atacagtttg ttcctcgtgg
1201 cggcgcatga gttcggccac gcgctgggct tagatcattc ctcagtgccg gaggcgctca
1261 tgtaccctat gtaccgcttc actgaggggc cccccttgca taaggacgac gtgaatggca
1321 tccggcacct ctatggtcct cgccctgaac ctgagccacg gcctccaacc accaccacac
1381 cgcagcccac ggctcccccg acggtctgcc ccaccggacc ccccactgtc cacccctcag
1441 agcgccccac agctggcccc acaggtcccc cctcagctgg ccccacaggt ccccccactg
1501 ctggcccttc tacggccact actgtgcctt tgagtccggt ggacgatgcc tgcaacgtga
1561 acatcttcga cgccatcgcg gagattggga accagctgta tttgttcaag gatgggaagt
1621 actggcgatt ctctgagggc agggggagcc ggccgcaggg ccccttcctt atcgccgaca
1681 agtggcccgc gctgccccgc aagctggact cggtctttga ggagccgctc tccaagaagc
1741 ttttcttctt ctctgggcgc caggtgtggg tgtacacagg cgcgtcggtg ctgggcccga
1801 ggcgtctgga caagctgggc ctgggagccg acgtggccca ggtgaccggg gccctccgga
1861 gtggcagggg gaagatgctg ctgttcagcg ggcggcgcct ctggaggttc gacgtgaagg
1921 cgcagatggt ggatccccgg agcgccagcg aggtggaccg gatgttcccc ggggtgcctt
1981 tggacacgca cgacgtcttc cagtaccgag agaaagccta tttctgccag gaccgcttct
2041 actggcgcgt gagttcccgg agtgagttga accaggtgga ccaagtgggc tacgtgacct
2101 atgacatcct gcagtgccct gaggactagg gctcccgtcc tgctttggca gtgccatgta
2161 aatccccact gggaccaacc ctggggaagg agccagtttg ccggatacaa actggtattc
2221 tgttctggag gaaagggagg agtggaggtg ggctgggccc tctcttctca cctttgtttt
2281 ttgttggagt gtttctaata aacttggatt ctctaacctt taaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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