LOCUS BC005978 1782 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1),
mRNA (cDNA clone MGC:14668 IMAGE:4105058), complete cds.
ACCESSION BC005978
VERSION BC005978.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1782)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1782)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 21 Row: p Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62388891.
FEATURES Location/Qualifiers
source 1..1782
/db_xref="H-InvDB:HIT000032568_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14668 IMAGE:4105058"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1782
/gene="KPNA2"
/gene_synonym="IPOA1"
/gene_synonym="QIP2"
/gene_synonym="SRP1alpha"
/db_xref="GeneID:3838"
/db_xref="HGNC:HGNC:6395"
/db_xref="MIM:600685"
CDS 130..1719
/gene="KPNA2"
/gene_synonym="IPOA1"
/gene_synonym="QIP2"
/gene_synonym="SRP1alpha"
/codon_start=1
/product="karyopherin alpha 2 (RAG cohort 1, importin
alpha 1)"
/protein_id="AAH05978.1"
/db_xref="GeneID:3838"
/db_xref="HGNC:HGNC:6395"
/db_xref="MIM:600685"
/translation="MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKD
DQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARK
LLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKVVVD
GGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDM
SSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAIS
YLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDA
GALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFK
TQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQA
AENLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVP
ETTSEGYTFQVQDGAPGTFNF"
BASE COUNT 518 a 407 c 403 g 454 t
ORIGIN
1 acacggtctt tgagctgagt cgaggtggac cctttgaacg cagtcgccct acagccgctg
61 attccccccg catcgcctcc cgtggaagcc caggcccgct tcgcagcttt ctccctttgt
121 ctcataacca tgtccaccaa cgagaatgct aatacaccag ctgcccgtct tcacagattc
181 aagaacaagg gaaaagacag tacagaaatg aggcgtcgca gaatagaggt caatgtggag
241 ctgaggaaag ctaagaagga tgaccagatg ctgaagagga gaaatgtaag ctcatttcct
301 gatgatgcta cttctccgct gcaggaaaac cgcaacaacc agggcactgt aaattggtct
361 gttgatgaca ttgtcaaagg cataaatagc agcaatgtgg aaaatcagct ccaagctact
421 caagctgcca ggaaactact ttccagagaa aaacagcccc ccatagacaa cataatccgg
481 gctggtttga ttccgaaatt tgtgtccttc ttgggcagaa ctgattgtag tcccattcag
541 tttgaatctg cttgggcact cactaacatt gcttctggga catcagaaca aaccaaggtt
601 gtggtagatg gaggtgccat cccagcattc atttctctgt tggcatctcc ccatgctcac
661 atcagtgaac aagctgtctg ggctctagga aacattgcag gtgatggctc agtgttccga
721 gacttggtta ttaagtacgg tgcagttgac ccactgttgg ctctccttgc agttcctgat
781 atgtcatctt tagcatgtgg ctacttacgt aatcttacct ggacactttc taatctttgc
841 cgcaacaaga atcctgcacc cccgatagat gctgttgagc agattcttcc taccttagtt
901 cggctcctgc atcatgatga tccagaagta ttagcagata cctgctgggc tatttcctac
961 cttactgatg gtccaaatga acgaattggc atggtggtga aaacaggagt tgtgccccaa
1021 cttgtgaagc ttctaggagc ttctgaattg ccaattgtga ctcctgccct aagagccata
1081 gggaatattg tcactggtac agatgaacag actcaggttg tgattgatgc aggagcactc
1141 gccgtctttc ccagcctgct caccaacccc aaaactaaca ttcagaagga agctacgtgg
1201 acaatgtcaa acatcacagc cggccgccag gaccagatac agcaagttgt gaatcatgga
1261 ttagtcccat tccttgtcag cgttctctct aaggcagatt ttaagacaca aaaggaagct
1321 gtgtgggccg tgaccaacta taccagtggt ggaacagttg aacagattgt gtaccttgtt
1381 cactgtggca taatagaacc gttgatgaac ctcttaactg caaaagatac caagattatt
1441 ctggttatcc tggatgccat ttcaaatatc tttcaggctg ctgagaacct aggtgaaact
1501 gagaaactta gtataatgat tgaagaatgt ggaggcttag acaaaattga agctctacaa
1561 aaccatgaaa atgagtctgt gtataaggct tcgttaagct taattgagaa gtatttctct
1621 gtagaggaag aggaagatca aaacgttgta ccagaaacta cctctgaagg ctacactttc
1681 caagttcagg atggggctcc tgggaccttt aacttttaga tcatgtagct gagacataaa
1741 tttgttgtgt gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//