LOCUS BC005861 2788 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens integrin, beta 2 (complement component 3 receptor 3
and 4 subunit), mRNA (cDNA clone MGC:3628 IMAGE:3532902), complete
cds.
ACCESSION BC005861
VERSION BC005861.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2788)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2788)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 31, 2003 this sequence version replaced BC005861.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 11 Row: p Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557885.
FEATURES Location/Qualifiers
source 1..2788
/db_xref="H-InvDB:HIT000032483"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3628 IMAGE:3532902"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2788
/gene="ITGB2"
/gene_synonym="LAD"
/gene_synonym="LCAMB"
/gene_synonym="LFA-1"
/gene_synonym="MAC-1"
/gene_synonym="MF17"
/db_xref="GeneID:3689"
/db_xref="HGNC:HGNC:6155"
/db_xref="MIM:600065"
CDS 45..2354
/gene="ITGB2"
/gene_synonym="LAD"
/gene_synonym="LCAMB"
/gene_synonym="LFA-1"
/gene_synonym="MAC-1"
/gene_synonym="MF17"
/codon_start=1
/product="ITGB2 protein"
/protein_id="AAH05861.1"
/db_xref="GeneID:3689"
/db_xref="HGNC:HGNC:6155"
/db_xref="MIM:600065"
/translation="MLGLRPPLLALVGLLSLGCVLSQECTKFKVSSCRECIESGPGCT
WCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQK
VTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEI
TESGRIGFGSFVDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQ
TEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLG
AILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLT
EIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTH
RNQPRGDCDGVQINVPITFQVKVTATECIQEQSFVIRALGFTDIVTVQVLPQCECRCR
DQSRDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSG
LGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHP
GFEGSACQCERTTEGCLNPRRVECSGRGRCRCNVCECHSGYQLPLCQECPGCPSPCGK
YISCAECLKFEKGPFGKNCSAACPGLQLSNNPVKGRTCKERDSEGCWVAYTLEQQDGM
DRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEK
EKLKSQWNNDNPLFKSATTTVMNPKFAES"
BASE COUNT 627 a 810 c 829 g 522 t
ORIGIN
1 gttgggcctg agaccgtcac caagacccct tccctccaca ggacatgctg ggcctgcgcc
61 ccccacttct cgccctggtg gggctgctct ccctcgggtg cgtcctctct caggagtgca
121 cgaagttcaa ggtcagcagc tgccgggaat gcatcgagtc ggggcccggc tgcacctggt
181 gccagaagct gaacttcaca gggccggggg atcctgactc cattcgctgc gacacccggc
241 cacagctgct catgaggggc tgtgcggctg acgacatcat ggaccccaca agcctcgctg
301 aaacccagga agaccacaat gggggccaga agcagctgtc cccacaaaaa gtgacgcttt
361 acctgcgacc aggccaggca gcagcgttca acgtgacctt ccggcgggcc aagggctacc
421 ccatcgacct gtactatctg atggacctct cctactccat gcttgatgac ctcaggaatg
481 tcaagaagct aggtggcgac ctgctccggg ccctcaacga gatcaccgag tccggccgca
541 ttggcttcgg gtccttcgtg gacaagaccg tgctgccgtt cgtgaacacg caccctgata
601 agctgcgaaa cccatgcccc aacaaggaga aagagtgcca gcccccgttt gccttcaggc
661 acgtgctgaa gctgaccaac aactccaacc agtttcagac cgaggtcggg aagcagctga
721 tttccggaaa cctggatgca cccgagggtg ggctggacgc catgatgcag gtcgccgcct
781 gcccggagga aatcggctgg cgcaacgtca cgcggctgct ggtgtttgcc actgatgacg
841 gcttccattt cgcgggcgac gggaagctgg gcgccatcct gacccccaac gacggccgct
901 gtcacctgga ggacaacttg tacaagagga gcaacgaatt cgactaccca tcggtgggcc
961 agctggcgca caagctggct gaaaacaaca tccagcccat cttcgcggtg accagtagga
1021 tggtgaagac ctacgagaaa ctcaccgaga tcatccccaa gtcagccgtg ggggagctgt
1081 ctgaggactc cagcaatgtg gtccatctca ttaagaatgc ttacaataaa ctctcctcca
1141 gggtattcct ggatcacaac gccctccccg acaccctgaa agtcacctac gactccttct
1201 gcagcaatgg agtgacgcac aggaaccagc ccagaggtga ctgtgatggc gtgcagatca
1261 atgtcccgat caccttccag gtgaaggtca cggccacaga gtgcatccag gagcagtcgt
1321 ttgtcatccg ggcgctgggc ttcacggaca tagtgaccgt gcaggtcctt ccccagtgtg
1381 agtgccggtg ccgggaccag agcagagacc gcagcctctg ccatggcaag ggcttcttgg
1441 agtgcggcat ctgcaggtgt gacactggct acattgggaa aaactgtgag tgccagacac
1501 agggccggag cagccaggag ctggaaggaa gctgccggaa ggacaacaac tccatcatct
1561 gctcagggct gggggactgt gtctgcgggc agtgcctgtg ccacaccagc gacgtccccg
1621 gcaagctgat atacgggcag tactgcgagt gtgacaccat caactgtgag cgctacaacg
1681 gccaggtctg cggcggcccg gggagggggc tctgcttctg cgggaagtgc cgctgccacc
1741 cgggctttga gggctcagcg tgccagtgcg agaggaccac tgagggctgc ctgaacccgc
1801 ggcgtgttga gtgtagtggt cgtggccggt gccgctgcaa cgtatgcgag tgccattcag
1861 gctaccagct gcctctgtgc caggagtgcc ccggctgccc ctcaccctgt ggcaagtaca
1921 tctcctgcgc cgagtgcctg aagttcgaaa agggcccctt tgggaagaac tgcagcgcgg
1981 cgtgtccggg cctgcagctg tcgaacaacc ccgtgaaggg caggacctgc aaggagaggg
2041 actcagaggg ctgctgggtg gcctacacgc tggagcagca ggacgggatg gaccgctacc
2101 tcatctatgt ggatgagagc cgagagtgtg tggcaggccc caacatcgcc gccatcgtcg
2161 ggggcaccgt ggcaggcatc gtgctgatcg gcattctcct gctggtcatc tggaaggctc
2221 tgatccacct gagcgacctc cgggagtaca ggcgctttga gaaggagaag ctcaagtccc
2281 agtggaacaa tgataatccc cttttcaaga gcgccaccac gacggtcatg aaccccaagt
2341 ttgctgagag ttaggagcac ttggtgaaga caaggccgtc aggacccacc atgtctgccc
2401 catcacgcgg ccgagacatg gcttgccaca gctcttgagg atgtcaccaa ttaaccagaa
2461 atccagttat tttccaccct caaaatgaca gccatggccg gccgggtgct tctgggggct
2521 cgtcgggggg acagctccac tctgactggc acagtctttg catggagact tgaggaggga
2581 gggcttgagg ttggtgaggt taggtgcgtg tttcctgtgc aagtcaggac atcagtctga
2641 ttaaaggtgg tgccaattta tttacattta aacttgtcag ggtataaaat gacatcccat
2701 taattatatt gttaatcaat cacgtgtata gaaaaaaaat aaaacttcaa tacaggctgt
2761 ccatggaaaa aaaaaaaaaa aaaaaaaa
//