LOCUS BC005298 1323 bp mRNA linear HUM 26-NOV-2007
DEFINITION Homo sapiens cyclin-dependent kinase 7, mRNA (cDNA clone MGC:12365
IMAGE:3997991), complete cds.
ACCESSION BC005298
VERSION BC005298.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1323)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1323)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: j Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16950659.
FEATURES Location/Qualifiers
source 1..1323
/db_xref="H-InvDB:HIT000032355_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12365 IMAGE:3997991"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1323
/gene="CDK7"
/gene_synonym="CAK1"
/gene_synonym="CDKN7"
/gene_synonym="MO15"
/gene_synonym="p39MO15"
/gene_synonym="STK1"
/db_xref="GeneID:1022"
/db_xref="HGNC:HGNC:1778"
/db_xref="MIM:601955"
CDS 89..1129
/gene="CDK7"
/gene_synonym="CAK1"
/gene_synonym="CDKN7"
/gene_synonym="MO15"
/gene_synonym="p39MO15"
/gene_synonym="STK1"
/codon_start=1
/product="cyclin-dependent kinase 7"
/protein_id="AAH05298.1"
/db_xref="GeneID:1022"
/db_xref="HGNC:HGNC:1778"
/db_xref="MIM:601955"
/translation="MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIK
LGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVII
KDNSLVLTPSHIKAYMLMTLQGLEYLHRHWILHRDLKPNNLLLDENGVLKLADFGLAK
SFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSD
LDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLF
LFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEA
LEQGGLPKKLIF"
BASE COUNT 440 a 234 c 293 g 356 t
ORIGIN
1 tgggtgttgg aggctttaag gtagctttaa attcgtgttg tcctgggagc tcgccctttt
61 cggctggagt cgggctttac ggcgccggat ggctctggac gtgaagtctc gggcaaagcg
121 ttatgagaag ctggacttcc ttggggaggg acagtttgcc accgtttaca aggccagaga
181 taagaacacc aaccaaattg tcgccattaa gaaaatcaaa cttggacata gatcagaagc
241 taaagatggt ataaatagaa ccgccttaag agagataaaa ttattacagg agctaagtca
301 tccaaatata attggtctcc ttgatgcttt tggacataaa tctaatatta gccttgtctt
361 tgattttatg gaaactgatc tagaggttat aataaaggat aatagtcttg tgctgacacc
421 atcacacatc aaagcctaca tgttgatgac tcttcaagga ttagaatatt tacatcgaca
481 ttggatccta catagggatc tgaaaccaaa caacttgttg ctagatgaaa atggagttct
541 aaaactggca gattttggcc tggccaaatc ttttgggagc cccaatagag cttatacaca
601 tcaggttgta accaggtggt atcgggcccc cgagttacta tttggagcta ggatgtatgg
661 tgtaggtgtg gacatgtggg ctgttggctg tatattagca gagttacttc taagggttcc
721 ttttttgcca ggagattcag accttgatca gctaacaaga atatttgaaa ctttgggcac
781 accaactgag gaacagtggc cggacatgtg tagtcttcca gattatgtga catttaagag
841 tttccctgga atacctttgc atcacatctt cagtgcagca ggagacgact tactagatct
901 catacaaggc ttattcttat ttaatccatg tgctcgaatt acggccacac aggcactgaa
961 aatgaagtat ttcagtaatc ggccagggcc aacacctgga tgtcagctgc caagaccaaa
1021 ctgtccagtg gaaaccttaa aggagcaatc aaatccagct ttggcaataa aaaggaaaag
1081 aacagaggcc ttagaacaag gaggattgcc caagaaacta attttttaaa gagaacactg
1141 gacaacattt tactactgag ggaaatagcc aaaaaggcaa ataatggaaa aatagtaaac
1201 attaagtaaa tgctgtagaa gtgagtttgt aaatattcta cacatgtaaa atatgtaaaa
1261 ctatgggtta tttttattaa atgtatttta aaacaaaaaa aaaaaaaaaa aaaaaaaaaa
1321 aaa
//