LOCUS BC005252 1489 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens geranylgeranyl diphosphate synthase 1, mRNA (cDNA
clone MGC:12287 IMAGE:4051481), complete cds.
ACCESSION BC005252
VERSION BC005252.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1489)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1489)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: l Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21359876.
FEATURES Location/Qualifiers
source 1..1489
/db_xref="H-InvDB:HIT000032322"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12287 IMAGE:4051481"
/tissue_type="Kidney, hypernephroma"
/clone_lib="NIH_MGC_58"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1489
/gene="GGPS1"
/gene_synonym="GGPPS"
/gene_synonym="GGPPS1"
/db_xref="GeneID:9453"
/db_xref="HGNC:HGNC:4249"
/db_xref="MIM:606982"
CDS 233..1135
/gene="GGPS1"
/gene_synonym="GGPPS"
/gene_synonym="GGPPS1"
/codon_start=1
/product="geranylgeranyl diphosphate synthase 1"
/protein_id="AAH05252.1"
/db_xref="GeneID:9453"
/db_xref="HGNC:HGNC:4249"
/db_xref="MIM:606982"
/translation="MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPED
KLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEK
VLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAV
GLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTI
HAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQID
ARGGNPELVALVKHLSKMFKEENE"
BASE COUNT 490 a 274 c 309 g 416 t
ORIGIN
1 agtgtgaccg ggatggcgca ttttcttgca ccaactaatg cggtgtcgct ggcggctgag
61 gagggcggag agttctgtgg tgaaatagtg ggaaggattc atgtaggcat cgggaagagc
121 ctaagtccac attataaaat aggaagttga tgcggggtac agttactccc ggaccggcgg
181 cgtgaaagtc gtgatatcat cgttgaacta ttagctttga agtttaaatc caatggagaa
241 gactcaagaa acagtccaaa gaattcttct agaaccctat aaatacttac ttcagttacc
301 aggtaaacaa gtgagaacca aactttcaca ggcatttaat cattggctga aagttccaga
361 ggacaagcta cagattatta ttgaagtgac agaaatgttg cataatgcca gtttactcat
421 cgatgatatt gaagacaact caaaactccg acgtggcttt ccagtggccc acagcatcta
481 tggaatccca tctgtcatca attctgccaa ttacgtgtat ttccttggct tggagaaagt
541 cttaaccctt gatcacccag atgcagtgaa gctttttacc cgccagcttt tggaactcca
601 tcagggacaa ggcctagata tttactggag ggataattac acttgtccca ctgaagaaga
661 atataaagct atggtgctgc agaaaacagg tggactgttt ggattagcag taggtctcat
721 gcagttgttc tctgattaca aagaagattt aaaaccgcta cttaatacac ttgggctctt
781 tttccaaatt agggatgatt atgctaatct acactccaaa gaatatagtg aaaacaaaag
841 tttttgtgaa gatctgacag agggaaagtt ctcatttcct actattcatg ctatttggtc
901 aaggcctgaa agcacccagg tgcagaatat cttgcgccag agaacagaaa acatagatat
961 aaaaaaatac tgtgtacatt atcttgagga tgtaggttct tttgaataca ctcgtaatac
1021 ccttaaagag cttgaagcta aagcctataa acagattgat gcacgtggtg ggaaccctga
1081 gctagtagcc ttagtaaaac acttaagtaa gatgttcaaa gaagaaaatg aataatgtta
1141 agccattctt gattggacct catagcttat tttagttaat cttttttttg tcttttagcc
1201 ttaccacctt ttaaaaaatt tgttattctc cagaaacagt aaataggtga gtaggggtgg
1261 tgcaagtgaa ttcgttttca tttagaagcc cctctgtaca gataatcaaa attcaaagtt
1321 gaaagaatca aaagcagcca cagttatgta ggtctgattt gaatgtcata attgcagtga
1381 caggacattg ccaccaactc tatcctacta ccatcaatgt tgtgtttatt ccgtcaataa
1441 aaaagacttg cttccaggca aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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