LOCUS BC005054 1128 bp mRNA linear HUM 09-MAR-2007
DEFINITION Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB
type, mRNA (cDNA clone MGC:12941 IMAGE:2822202), complete cds.
ACCESSION BC005054
VERSION BC005054.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1128)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1128)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: a Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41053624.
FEATURES Location/Qualifiers
source 1..1128
/db_xref="H-InvDB:HIT000086441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12941 IMAGE:2822202"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1128
/gene="MMAB"
/gene_synonym="ATR"
/db_xref="GeneID:326625"
/db_xref="HGNC:HGNC:19331"
/db_xref="MIM:607568"
CDS 14..766
/gene="MMAB"
/gene_synonym="ATR"
/codon_start=1
/product="methylmalonic aciduria (cobalamin deficiency)
cblB type"
/protein_id="AAH05054.2"
/db_xref="GeneID:326625"
/db_xref="HGNC:HGNC:19331"
/db_xref="MIM:607568"
/translation="MAVCGLGSRLGLGSRLGLQGCFGAARLLYPRFQSRGPQGVEDGD
RPQPSSKTPRIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALEL
VTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKY
TSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSD
YLFTLARYAAMKEGNQEKIYKKNDPSAESEGL"
BASE COUNT 297 a 289 c 322 g 220 t
ORIGIN
1 agcagcctgg ctcatggctg tgtgcggcct ggggagccgt cttggcctgg ggagccgtct
61 tggcctgcaa gggtgcttcg gcgccgccag gctcctgtat ccccgtttcc agagccgcgg
121 ccctcagggc gtggaagacg gggacaggcc acagccttcc tcgaagacac ccaggatccc
181 caagatttac accaaaacgg gagacaaagg gttttctagt accttcacag gagaaaggag
241 acccaaagat gaccaagtgt ttgaagccgt gggaactaca gatgaattaa gttcagctat
301 tgggtttgct ctggaattag tcacagaaaa gggccataca tttgccgaag agcttcagaa
361 aatccagtgc acattgcagg acgtcggctc ggccctggcg acaccatgct cctcggcccg
421 ggaggctcac ttaaagtata ccacgttcaa ggcggggccc atcctggagc tggagcagtg
481 gatcgacaag tacaccagcc agctcccacc actcacggcc ttcatcctgc cttcgggagg
541 caagatcagc tcggcgctgc atttctgccg ggccgtgtgc cgccgggccg agagacgtgt
601 ggtgcctctt gtccagatgg gagagaccga tgcgaacgtg gccaagttct taaacagact
661 cagtgactat ctcttcacgc tagccagata tgcagccatg aaggagggga atcaagagaa
721 aatatacaag aaaaatgacc catcggccga gtctgaggga ctctgaaatc acagaaagtg
781 ggagcttgga ggatccctcc atggcgatgg ccgtggagag aggagcttgc ccttctgggg
841 tcctggttcc tgaagagctc acccagagag gctcaaagca gccttttgtc ccagctcagc
901 tttgatctac acctcttgcc accttcctca agggactgtg accctttggg gattctgtcc
961 ctgaccctgc ttccccaagc tctcctaggt cttggaggga tgtgggaatg aattggcatt
1021 gcaggaaaga caggtaaagt gattgctgca atgagaagga gctgtgcgga aaaggaataa
1081 aagttggaaa ggcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//