LOCUS BC005046 1619 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens vitronectin, mRNA (cDNA clone MGC:12819
IMAGE:4040317), complete cds.
ACCESSION BC005046
VERSION BC005046.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1619)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1619)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: o Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18201910.
FEATURES Location/Qualifiers
source 1..1619
/db_xref="H-InvDB:HIT000032180"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12819 IMAGE:4040317"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1619
/gene="VTN"
/gene_synonym="V75"
/gene_synonym="VN"
/gene_synonym="VNT"
/db_xref="GeneID:7448"
/db_xref="HGNC:HGNC:12724"
/db_xref="MIM:193190"
CDS 81..1517
/gene="VTN"
/gene_synonym="V75"
/gene_synonym="VN"
/gene_synonym="VNT"
/codon_start=1
/product="vitronectin"
/protein_id="AAH05046.1"
/db_xref="GeneID:7448"
/db_xref="HGNC:HGNC:12724"
/db_xref="MIM:193190"
/translation="MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELC
SYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDL
QAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKP
FDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGK
TYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKG
KQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQF
ISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQN
SRRPSRAMWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLR
TRRVDTVDPPYPRSIAQYWLGCPAPGHL"
BASE COUNT 359 a 504 c 447 g 309 t
ORIGIN
1 ctcccttcct caggcatcag agcggagact tcagggagac cagagcccag cttgccaggc
61 actgagctag aagccctgcc atggcacccc tgagacccct tctcatactg gccctgctgg
121 catgggttgc tctggctgac caagagtcat gcaagggccg ctgcactgag ggcttcaacg
181 tggacaagaa gtgccagtgt gacgagctct gctcttacta ccagagctgc tgcacagact
241 atacggctga gtgcaagccc caagtgactc gcggggatgt gttcactatg ccggaggatg
301 agtacacggt ctatgacgat ggcgaggaga aaaacaatgc cactgtccat gaacaggtgg
361 ggggcccctc cctgacctct gacctccagg cccagtccaa agggaatcct gagcagacac
421 ctgttctgaa acctgaggaa gaggcccctg cgcctgaggt gggcgcctct aagcctgagg
481 ggatagactc aaggcctgag acccttcatc cagggagacc tcagccccca gcagaggagg
541 agctgtgcag tgggaagccc ttcgacgcct tcaccgacct caagaacggt tccctctttg
601 ccttccgagg gcagtactgc tatgaactgg acgaaaaggc agtgaggcct gggtacccca
661 agctcatccg agatgtctgg ggcatcgagg gccccatcga tgccgccttc acccgcatca
721 actgtcaggg gaagacctac ctcttcaagg gtagtcagta ctggcgcttt gaggatggtg
781 tcctggaccc tgattacccc cgaaatatct ctgacggctt cgatggcatc ccggacaacg
841 tggatgcagc cttggccctc cctgcccata gctacagtgg ccgggagcgg gtctacttct
901 tcaaggggaa acagtactgg gagtaccagt tccagcacca gcccagtcag gaggagtgtg
961 aaggcagctc cctgtcggct gtgtttgaac actttgccat gatgcagcgg gacagctggg
1021 aggacatctt cgagcttctc ttctggggca gaacctctgc tggtaccaga cagccccagt
1081 tcattagccg ggactggcac ggtgtgccag ggcaagtgga cgcagccatg gctggccgca
1141 tctacatctc aggcatggca ccccgcccct ccttggccaa gaaacaaagg tttaggcatc
1201 gcaaccgcaa aggctaccgt tcacaacgag gccacagccg tggccgcaac cagaactccc
1261 gccggccatc ccgcgccatg tggctgtcct tgttctccag tgaggagagc aacttgggag
1321 ccaacaacta tgatgactac aggatggact ggcttgtgcc tgccacctgt gaacccatcc
1381 agagtgtctt cttcttctct ggagacaagt actaccgagt caatcttcgc acacggcgag
1441 tggacactgt ggaccctccc tacccacgct ccatcgctca gtactggctg ggctgcccag
1501 ctcctggcca tctgtaggag tcagagccca catggccggg ccctctgtag ctccctcctc
1561 ccatctcctt cccccagccc aataaaggtc ccttagcccc gaaaaaaaaa aaaaaaaaa
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