LOCUS BC005041 2072 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase inhibitor 2C (p18, inhibits
CDK4), mRNA (cDNA clone MGC:12768 IMAGE:3160354), complete cds.
ACCESSION BC005041
VERSION BC005041.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2072)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2072)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: c Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17981697.
FEATURES Location/Qualifiers
source 1..2072
/db_xref="H-InvDB:HIT000258908"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12768 IMAGE:3160354"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2072
/gene="CDKN2C"
/gene_synonym="INK4C"
/gene_synonym="p18"
/gene_synonym="p18-INK4C"
/db_xref="GeneID:1031"
/db_xref="HGNC:HGNC:1789"
/db_xref="MIM:603369"
CDS 1189..1695
/gene="CDKN2C"
/gene_synonym="INK4C"
/gene_synonym="p18"
/gene_synonym="p18-INK4C"
/codon_start=1
/product="cyclin-dependent kinase inhibitor 2C (p18,
inhibits CDK4)"
/protein_id="AAH05041.1"
/db_xref="GeneID:1031"
/db_xref="HGNC:HGNC:1789"
/db_xref="MIM:603369"
/translation="MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV
MKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE
GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG
AGGATNLQ"
BASE COUNT 508 a 548 c 592 g 424 t
ORIGIN
1 gttaaaatgg gggcgggttt ttcaactcaa aaagcgctca atttttttct tttcaaaaaa
61 agctgatgag gtcggaaaaa agggagaaga aaccggcacc ctctctgaga ggcaacagaa
121 gcagcaattg tttcagcgaa aaaagcagca agggagggag tgaaggaaaa aagcaaaaaa
181 gggggcgaca cgcaagtgcc tgtaggggtg aaaggagcag ggaccggcga tctagggggg
241 gatcagctac aaaagaaact gtcactggga gcggtgcggc caaggaggaa gcagtgctgc
301 caggctctgc tccagggcac agctggctgg cggctgccct gtccgcagca aaggggcaca
361 ggccggggac cgcgagaggt ggcaaagtgg caccgggcgc cgaggctgct gagcgctcgc
421 cgagacggcg accggactgg ctgccccgga actgcggcga ctctccctac tcagaacttg
481 gcctacgttt cccaggactc tccccatctc cagaggcccc cacaaaaccg ggaaaggaag
541 gaaaggacag cggcggcagc agctcaatga gtgcctacag cagaaagcct gaacgagctc
601 ggtcgtaggc gggaagttcc cgggggggct gcccagtgca gccgcaatgc tgccgcgagc
661 tgccccagca gtccgggctc cgtagacgct ttccgcatca ctctccttcc tcgggctgcc
721 gggagtcccg ggacctggcg gggccggcat gacgggcttc tcgggggccc gccgcacgcc
781 cggcagcctc cggagacgcg cgccgagccc ggctcccacg gcctctgagg ctcggcgggg
841 ctgcggctgc ctggcgggcg ggctccggag ctttcctgag cggcattagc ccacggcttg
901 gcccggacgc gaccaaaggc tcttctggag aagcccagag cactgggcaa tcgttacgac
961 ctgtaacttg agggccaccg aactgctact cccgttcgcc tttggcgatc atcttttaac
1021 cctccggagc acgtcagcat ccagccaccg cggcgctctc ccagcagcgg aggacccagg
1081 actatccctt cggcgagacg gatggaaacc gagccccctg gaggacctgc ccctgcagtt
1141 ctgcctcaca cggctcaagt caccaccgtg aacaagggac cctaaagaat ggccgagcct
1201 tgggggaacg agttggcgtc cgcagctgcc aggggggacc tagagcaact tactagtttg
1261 ttgcaaaata atgtaaacgt caatgcacaa aatggatttg gaaggactgc gctgcaggtt
1321 atgaaacttg gaaatcccga gattgccagg agactgctac ttagaggtgc taatcccgat
1381 ttgaaagacc gaactggttt cgctgtcatt catgatgcgg ccagagcagg tttcctggac
1441 actttacaga ctttgctgga gtttcaagct gatgttaaca tcgaggataa tgaagggaac
1501 ctgcccttgc acttggctgc caaagaaggc cacctccggg tggtggagtt cctggtgaag
1561 cacacggcca gcaatgtggg gcatcggaac cataaggggg acaccgcctg tgatttggcc
1621 aggctctatg ggaggaatga ggttgttagc ctgatgcagg caaacggggc tgggggagcc
1681 acaaatcttc aataaacgtg gggagggctc ccccacgttg cctctacttt atcaattaac
1741 tgagtagctc tcctgacttt taatgtcatt tgttaaaata cagttctgtc atatgttaag
1801 cagctaaatt ttctgaaact gcataagtga aaatcttaca acaggcttat gaatatattt
1861 aagcaacatc tttttaacct gcaaaatctg ttctaacatg taattgcaga taactttgac
1921 tttcttctga atattttatc tttccttggc ttttcccttg cttccccttt tgccaatctc
1981 aacacccaag ttgaagactt tgtttttaaa atggtttgtc ctgatgcttt tgtctaatta
2041 aaacactttc aaaaaaaaaa aaaaaaaaaa aa
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