LOCUS BC005026 1600 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sirtuin (silent mating type information regulation 2
homolog) 6 (S. cerevisiae), mRNA (cDNA clone MGC:12574
IMAGE:2820472), complete cds.
ACCESSION BC005026
VERSION BC005026.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1600)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1600)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: a Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7706709.
FEATURES Location/Qualifiers
source 1..1600
/db_xref="H-InvDB:HIT000032167"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12574 IMAGE:2820472"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1600
/gene="SIRT6"
/gene_synonym="SIR2L6"
/db_xref="GeneID:51548"
/db_xref="HGNC:HGNC:14934"
/db_xref="MIM:606211"
CDS 4..1071
/gene="SIRT6"
/gene_synonym="SIR2L6"
/codon_start=1
/product="sirtuin (silent mating type information
regulation 2 homolog) 6 (S. cerevisiae)"
/protein_id="AAH05026.1"
/db_xref="GeneID:51548"
/db_xref="HGNC:HGNC:14934"
/db_xref="MIM:606211"
/translation="MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQS
SSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLE
RVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLK
ATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQ
IRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAW
DGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRE
RPTSPAPHRPPKRVKAKAVPS"
BASE COUNT 307 a 530 c 496 g 267 t
ORIGIN
1 aggatgtcgg tgaattacgc ggcggggctg tcgccgtacg cggacaaggg caagtgcggc
61 ctcccggaga tcttcgaccc cccggaggag ctggagcgga aggtgtggga actggcgagg
121 ctggtctggc agtcttccag tgtggtgttc cacacgggtg ccggcatcag cactgcctct
181 ggcatccccg acttcagggg tccccacgga gtctggacca tggaggagcg aggtctggcc
241 cccaagttcg acaccacctt tgagagcgcg cggcccacgc agacccacat ggcgctggtg
301 cagctggagc gcgtgggcct cctccgcttc ctggtcagcc agaacgtgga cgggctccat
361 gtgcgctcag gcttccccag ggacaaactg gcagagctcc acgggaacat gtttgtggaa
421 gaatgtgcca agtgtaagac gcagtacgtc cgagacacag tcgtgggcac catgggcctg
481 aaggccacgg gccggctctg caccgtggct aaggcaaggg ggctgcgagc ctgcagggga
541 gagctgaggg acaccatcct agactgggag gactccctgc ccgaccggga cctggcactc
601 gccgatgagg ccagcaggaa cgccgacctg tccatcacgc tgggtacatc gctgcagatc
661 cggcccagcg ggaacctgcc gctggctacc aagcgccggg gaggccgcct ggtcatcgtc
721 aacctgcagc ccaccaagca cgaccgccat gctgacctcc gcatccatgg ctacgttgac
781 gaggtcatga cccggctcat gaagcacctg gggctggaga tccccgcctg ggacggcccc
841 cgtgtgctgg agagggcgct gccacccctg ccccgcccgc ccacccccaa gctggagccc
901 aaggaggaat ctcccacccg gatcaacggc tctatccccg ccggccccaa gcaggagccc
961 tgcgcccagc acaacggctc agagcccgcc agccccaaac gggagcggcc caccagccct
1021 gccccccaca gaccccccaa aagggtgaag gccaaggcgg tccccagctg accagggtgc
1081 ttggggaggg tggggctttt tgtagaaact gtggattctt tttctctcgt ggtctcactt
1141 tgttacttgt ttctgtcccc gggagcctca gggctctgag agctgtgctc caggccaggg
1201 gttacacctg ccctccgtgg tccctccctg ggctccaggg gcctctggtg cggttccggg
1261 aagaagccac accccagagg tgacagctga gcccctgcca caccccagcc tctgacttgc
1321 tgtgttgtcc agaggtgagg ctgggccctc cctggtctcc agcttaaaca ggagtgaact
1381 ccctctgtcc ccagggcctc ccttctgggc cccctacagc ccaccctacc cctcctccat
1441 gggccctgca ggaggggaga cccaccttga agtgggggat cagtagaggc ttgcactgcc
1501 tttggggctg gagggagacg tgggtccacc aggcttctgg aaaagtcctc aatgcaataa
1561 aaacaatttc tttcttgcaa aaaaaaaaaa aaaaaaaaaa
//