LOCUS BC004966 1790 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens solute carrier family 10 (sodium/bile acid
cotransporter family), member 3, mRNA (cDNA clone MGC:2336
IMAGE:3503242), complete cds.
ACCESSION BC004966
VERSION BC004966.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1790)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1790)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: j Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10938005.
FEATURES Location/Qualifiers
source 1..1790
/db_xref="H-InvDB:HIT000032117"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2336 IMAGE:3503242"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1790
/gene="SLC10A3"
/gene_synonym="DXS253E"
/gene_synonym="P3"
/db_xref="GeneID:8273"
/db_xref="MIM:312090"
CDS 216..1562
/gene="SLC10A3"
/gene_synonym="DXS253E"
/gene_synonym="P3"
/codon_start=1
/product="SLC10A3 protein"
/protein_id="AAH04966.1"
/db_xref="GeneID:8273"
/db_xref="MIM:312090"
/translation="MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQG
TASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPG
PMLRVTSLDTEVLTIKNLVDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSE
NPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKV
FMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAI
YSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLL
LGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEV
GVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP"
misc_feature 717..1271
/gene="SLC10A3"
/gene_synonym="DXS253E"
/gene_synonym="P3"
/note="SBF; Region: Sodium Bile acid symporter family.
This family consists of Na+/bile acid co-transporters.
These transmembrane proteins function in the liver in the
uptake of bile acids from portal blood plasma a process
mediated by the co-transport of Na+. Also in the family is
ARC3 from S. cerevisiae, a putative transmembrane protein
involved in resistance to arsenic compounds"
/db_xref="CDD:pfam01758"
BASE COUNT 352 a 574 c 479 g 385 t
ORIGIN
1 gctgcgcggt ggctgtggca ggttcgcgcc cgagctctgc tagccacccg tccgacaact
61 tccggactcc cagggacagc cctgccatca aggaagacag cacaggactg ggacccaccc
121 atgaaccctt ctcaggacaa cccaacagca ccagtgggga tgttctccta agccgcagag
181 ggcctgggca cgccatccgt cctccaggaa gagccatggt gttaatgcag gacaagggca
241 gctctcagca gtggcctggt ctggggggcg agggtggtgg cacaggtccc ttaagcatgc
301 tcagagctgc cctgctgctc atcagcctgc catggggggc ccaagggaca gccagcacca
361 gcctcagcac tgctgggggt cacaccgtgc caccgactgg gggccgctac ttgagcattg
421 gagatggctc tgtgatggag tttgagtttc ctgaggacag tgagggcatc atcgtgatct
481 ccagccagta cccaggccag gccaacagga cggcgcctgg ccccatgctc agggtcacct
541 ccctggacac agaggtgctg accatcaaga acctcgtgga cgcccatgag gccccgccca
601 cactgattga ggagcggaga gacttctgca tcaaggtctc acctgctgaa gacacgcctg
661 ccaccctcag cgccgacctg gcccacttct cggaaaaccc aatcctctac ctgctcctgc
721 ctcttatctt tgtcaacaag tgttcgtttg ggtgcaaagt ggaactcgag gttctgaagg
781 ggctcatgca gagcccccag cccatgctgc tgggcctcct gggccagttt ctggtcatgc
841 ccttgtacgc tttcctcatg gccaaggtct tcatgctgcc caaggccctg gctctgggcc
901 tcatcatcac ctgctcgtcg cctggcggcg gggggagcta cctcttcagc ctccttcttg
961 gaggggacgt caccctggcc atctccatga ctttcctctc tacggtggct gccactggct
1021 tcttgcctct gtcttcggcc atctacagcc gcctgctcag catccatgag acgctccacg
1081 tgcccatctc caagatcctg gggaccctgc tgttcattgc catccccata gccgtgggcg
1141 tgctgatcaa gtccaagctc cccaagttct cccagctgct gctgcaggtc gtcaagccct
1201 tcagctttgt gctcctcctg ggcggcctct tcctggccta tcgcatgggg gtcttcatcc
1261 tggcaggcat ccggctaccc atcgtactgg tgggtatcac ggtgcccctg gttggcctgt
1321 tggtgggcta ctgcctagcc acgtgtctga agctgccagt ggcccagcgg cggacggtca
1381 gcattgaggt aggggtgcag aacagcctgc tggccttggc catgctgcag ctatccctcc
1441 gccgccttca agctgactat gcctcccagg cccccttcat tgtggcgctg agcggcacct
1501 ccgagatgct ggccttggtc attggccact tcatctacag cagcctgttc ccagttccct
1561 gaggcctctg ggtcaagctt tcattagccc cagcccccac actccaccaa agttctcatg
1621 cactatgcac tcagaaaaat ccaggcttat tttttttact gattttttat tctccagctt
1681 tcagtgccaa agaggccatg ctgagttagg taggtgggcg ctgcccagaa aatatatttc
1741 aataaaagag agaagcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//