LOCUS BC004964 4199 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens oxoglutarate (alpha-ketoglutarate) dehydrogenase
(lipoamide), mRNA (cDNA clone MGC:1693 IMAGE:3528538), complete
cds.
ACCESSION BC004964
VERSION BC004964.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4199)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4199)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: i Column: 5.
FEATURES Location/Qualifiers
source 1..4199
/db_xref="H-InvDB:HIT000032115"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1693 IMAGE:3528538"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4199
/gene="OGDH"
/gene_synonym="AKGDH"
/gene_synonym="E1k"
/gene_synonym="OGDC"
/db_xref="GeneID:4967"
/db_xref="HGNC:HGNC:8124"
/db_xref="MIM:203740"
CDS 43..3114
/gene="OGDH"
/gene_synonym="AKGDH"
/gene_synonym="E1k"
/gene_synonym="OGDC"
/codon_start=1
/product="oxoglutarate (alpha-ketoglutarate) dehydrogenase
(lipoamide)"
/protein_id="AAH04964.1"
/db_xref="GeneID:4967"
/db_xref="HGNC:HGNC:8124"
/db_xref="MIM:203740"
/translation="MFHLRTCAAKLRPLTASQTVKTFSQNRPAAARTFQQIRCYSAPV
AAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRG
SLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSS
VPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHI
GVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEK
RFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFD
SKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQ
FYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTT
DPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCY
RRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKIC
EEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSV
PVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGT
FSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNAL
VLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERF
LQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLII
FTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTR
ERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPR
LRTTISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFKNFS"
BASE COUNT 943 a 1210 c 1145 g 901 t
ORIGIN
1 ctgagccgga gacaggcagt tgtgaaaaac ttcaggacaa aaatgtttca tttaaggact
61 tgtgctgcta agttgagacc attgacggct tcccagactg ttaagacatt ttcacaaaac
121 agaccagcag cagctaggac atttcaacag attcggtgct attctgcacc tgttgctgct
181 gagccctttc tcagtgggac tagttcgaac tatgtggagg agatgtactg tgcttggctg
241 gaaaacccca aaagtgtaca taagtcatgg gacatttttt ttcgcaacac gaatgccgga
301 gccccaccgg gcactgccta ccagagtccc cttcccctga gccgaggctc cctggctgct
361 gtggcccatg cacagtccct ggtagaagca cagcccaacg tggacaagct cgtggaggac
421 cacctggcag tgcagtcgct catcagggca tatcagatac gagggcacca tgtagcacag
481 ctggaccccc tggggatttt ggatgctgat ctggactcct ccgtgcccgc tgacattatc
541 tcatccacag acaaacttgg gttctatggc ctggatgagt ctgacctcga caaggtcttc
601 cacttgccca ccaccacttt catcggggga caggaatcag cacttcctct gcgggagatc
661 atccgtcggc tggagatggc ctactgccag catattgggg tggagttcat gttcatcaat
721 gacctggagc agtgccagtg gatccggcag aagtttgaga cccctgggat catgcagttc
781 acaaatgagg agaaacggac cctgctggcc aggcttgtgc ggtccaccag gtttgaggag
841 ttcctacagc ggaagtggtc ctctgagaag cgctttggtc tagaaggctg cgaggtactg
901 atccctgccc tcaagaccat cattgacaag tctagtgaga atggcgtgga ctacgtgatc
961 atgggcatgc cacacagagg gcggctgaac gtgcttgcaa atgtcatcag gaaggagctg
1021 gaacagatct tctgtcaatt cgattcaaag ctggaggcag ctgatgaggg ctccggagat
1081 gtgaagtacc acctgggcat gtatcaccgc aggatcaatc gtgtcaccga caggaacatt
1141 accttgtcct tggtggccaa cccttcccac cttgaggccg ctgaccccgt ggtgatgggc
1201 aagaccaaag ccgaacagtt ttactgtggc gacactgaag ggaaaaaggt catgtccatc
1261 ctgttgcatg gggatgctgc atttgctggc cagggcattg tgtacgagac cttccacctc
1321 agcgacctgc catcctacac aactcatggc accgtgcacg tggtcgtcaa caaccagatc
1381 ggcttcacca ccgaccctcg gatggcccgc tcctccccct accccactga cgtggcccga
1441 gtggtgaatg cccccatttt ccacgtgaac tcagatgacc ccgaggctgt catgtacgtg
1501 tgcaaagtgg cggccgagtg gaggagcacc ttccacaagg acgtggttgt cgatttggtg
1561 tgttaccggc gcaacggcca caacgagatg gatgagccca tgttcacgca gccgctcatg
1621 tacaagcaga tccgcaagca gaagcctgtg ttacagaagt acgctgagct gctggtgtcg
1681 cagggtgtgg tcaaccagcc tgagtatgag gaggaaattt ccaagtatga taagatctgt
1741 gaggaagctt ttgccagatc taaagatgag aagatcttgc acattaagca ctggctggac
1801 tctccctggc ctggcttctt caccctggac gggcagccca ggagcatgtc ctgcccctcc
1861 acgggtctga cggaggatat tctgacacac atcgggaatg tggctagttc tgtgcctgtg
1921 gaaaacttta ctattcatgg agggctgagc cggatcttga agactcgtgg ggaaatggtg
1981 aagaaccgga ctgtggactg ggctctagcg gagtacatgg cgtttggctc gctcctgaag
2041 gagggcatcc acattcggct gagcggccag gacgtggagc ggggcacatt cagccaccgc
2101 caccatgtgc tccatgacca gaatgtggac aagagaacct gcatccccat gaaccatctc
2161 tggcccaatc aggcccccta tactgtgtgc aacagctcac tgtctgagta cggcgtgctg
2221 ggctttgagc tgggcttcgc catggccagt cctaatgccc tggtcctctg ggaagcccaa
2281 tttggtgact tccacaacac ggcccagtgt atcatcgacc agttcatctg cccgggacaa
2341 gccaagtggg tgcggcagaa tggcatcgtg ttgctgctgc cccatggcat ggagggcatg
2401 ggtccagaac attcctccgc ccgcccagag cggttcttgc agatgtgcaa cgatgaccca
2461 gatgtcctgc cagaccttaa agaagccaac ttcgacatca atcagctata tgactgcaat
2521 tgggttgttg tcaactgctc cactcctggc aacttcttcc acgtgctacg acgccagatc
2581 ctgctgccat tccggaagcc gttaattatc ttcaccccca aatccctgtt gcgccacccc
2641 gaggccagat ccagctttga tgagatgctt ccaggaaccc acttccagcg ggtgatccca
2701 gaagatggcc ctgcagctca gaacccagaa aatgtcaaaa ggcttctctt ctgcaccggc
2761 aaagtgtatt atgacctcac ccgggagcgc aaagcacgcg acatggtggg gcaggtggcc
2821 atcacaagga ttgagcagct gtcgccattc ccctttgacc tcctgctgaa ggaggtgcag
2881 aagtacccca atgctgagct ggcctggtgc caggaggagc acaagaacca aggctactat
2941 gactacgtga agccaagact tcggaccacc atcagccgcg ccaagcccgt ctggtatgcc
3001 ggccgggacc cagcggctgc tccagccacc ggcaacaaga agacccacct gacggagctg
3061 cagcgcctcc tggacacggc cttcgacctg gacgtcttca agaacttctc gtagatgctg
3121 cctagggttg cttgggccac tgccctctcc acacccatga ctgccccttg cttctcaact
3181 aaagaatagt gcctcagcgc tgcccacacc accgccctcc tcgctgtgcc accacccctc
3241 cctctgctct cataggagtt aggctgtcgt ccccctccag tgcttggctg ccccacaggc
3301 cacacgctgc ccaggctctg ctgacttctg agcagttttc caggaggccg gggggagcag
3361 gagcaggaaa ggtagccccc gagggatgtc cttggggagg ggtcagctct ggccacaatc
3421 ctccccacca gtctcaccca ctaggatagg aactgggcct tgtgtgctgg cttccgctgt
3481 cacccagcaa ggcacaggct cctgtatttg agactaggat agcttcatct tgagcctgag
3541 ccttagaatc tgtagaggag cctggagtcg gatctagcca tggctggcag aggtttctag
3601 ggtgggcccc agccgtggcg tgaactgagg atgacccggg gcagctggca ggagagagcc
3661 ttggcctgac ctggcacaga aagggcagct tcagtctctg cagtgtccat tatctgctgt
3721 tccttcgagg gttccaggct gtgtgtgggg cccaagcatg ccccacccac ccctcctggg
3781 cccaggcagc acctggagcc cacagagtct gtgtgtagcc aggaagcccc gctcaggtag
3841 ccaccgccgg ggcactggct gctctgtctt ggtcctgtta accctccacc tcctctcttg
3901 gactccctcc ccaccccaac cactctttct ttctccttta acccaatgga gactttctga
3961 tgcatcgttt tctttgctgt gccaaagcag gtcagaagag ggagaggagg ggctgggggt
4021 gaggggccag gccatggcca aggggccagc tgcccctcat ttatcactct gaccttcaca
4081 gggacagatc tgatttattt attttggtta aaaaaaaaaa aaaggaacag aaacaacttt
4141 gcattgcatt ggcttgaccc ataaactaag ttatatccgt gaaaaaaaaa aaaaaaaaa
//