LOCUS BC004887 982 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens LanC lantibiotic synthetase component C-like 2
(bacterial), mRNA (cDNA clone IMAGE:3838053), partial cds.
ACCESSION BC004887
VERSION BC004887.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 982)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 982)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC004887.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: a Column: 6.
FEATURES Location/Qualifiers
source 1..982
/db_xref="H-InvDB:HIT000086409"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3838053"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..982
/gene="LANCL2"
/gene_synonym="GPR69B"
/gene_synonym="TASP"
/db_xref="GeneID:55915"
CDS <1..759
/gene="LANCL2"
/gene_synonym="GPR69B"
/gene_synonym="TASP"
/codon_start=1
/product="LANCL2 protein"
/protein_id="AAH04887.2"
/db_xref="GeneID:55915"
/translation="GRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREE
RKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKK
FRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRG
LLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYS
LFEGMAGAIHFLSDVLGPETSRFPAFELDSSKRD"
misc_feature 1..738
/gene="LANCL2"
/gene_synonym="GPR69B"
/gene_synonym="TASP"
/note="LANC_like; Region: Lanthionine synthetase C-like
protein. This family contains the lanthionine synthetase
C-like proteins 1 and 2 which are related to the bacterial
lanthionine synthetase components C (LanC). LANCL1(P40
seven-transmembrane-domain protein) and LANCL2
(testes-specific adriamycin sensitivity protein) are
thought to be peptide-modifying enzyme components in
eukaryotic cells. Both proteins are produced in large
quantities in the brain and testes and may have role in
the immune surveillance of these organs"
/db_xref="CDD:pfam05147"
BASE COUNT 289 a 225 c 248 g 220 t
ORIGIN
1 ggacgggcag gttatctgta tgccttactg tacctgaaca cagagatagg tccaggcacc
61 gtgtgtgagt cagctattaa agaggtagtc aatgctatta ttgaatcggg taagactttg
121 tcaagggaag aaagaaaaac ggagcgctgc ccgctgttgt accagtggca ccggaagcag
181 tacgttggag cagcccatgg catggctgga atttactata tgttaatgca gccggcagca
241 aaagtggacc aagaaacctt gacagaaatg gtgaaaccca gtattgatta tgtgcgccac
301 aaaaaattcc gatctgggaa ttacccatca tcattaagca atgaaacaga ccggctggtg
361 cactggtgcc acggcgcccc gggggtcatc cacatgctca tgcaggcgta caaggtcttt
421 aaggaggaga agtacttgaa agaggccatg gagtgtagcg atgtgatttg gcagcgaggt
481 ttgctgcgga agggctacgg gatatgccat gggactgctg gcaacggcta ttccttcctg
541 tccctttacc gtctcacgca ggataagaag tacctctacc gagcttgcaa gtttgcagag
601 tggtgtctag attacggagc acacgggtgc cgcattcctg acagacccta ttcgctcttt
661 gaaggcatgg ctggcgctat tcactttctc tctgatgtcc tgggaccaga gacatcacgg
721 tttccagcat ttgaacttga ctcttcgaag agggattaaa aggtgcaaaa agacaactaa
781 aatacccatt tggaccaaaa gccgccagat tgcttagtgc ctgacagaaa caactgggaa
841 tcctgaaaga gaagcagaca ccgtcacagg cccctctggt tagactagca tgagtgaccg
901 aagccatcca tcaacatttt ctaacagcac cctcatcaat ataaaatatg acttcttcac
961 atacaaaaaa aaaaaaaaaa aa
//