LOCUS BC004375 4202 bp mRNA linear HUM 14-SEP-2006
DEFINITION Homo sapiens 24-dehydrocholesterol reductase, mRNA (cDNA clone
MGC:10569 IMAGE:3638639), complete cds.
ACCESSION BC004375
VERSION BC004375.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4202)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4202)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: f Column: 10.
FEATURES Location/Qualifiers
source 1..4202
/db_xref="H-InvDB:HIT000031900"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10569 IMAGE:3638639"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4202
/gene="DHCR24"
/gene_synonym="KIAA0018"
/gene_synonym="Nbla03646"
/gene_synonym="seladin-1"
/gene_synonym="SELADIN1"
/db_xref="GeneID:1718"
/db_xref="HGNC:HGNC:2859"
/db_xref="MIM:606418"
CDS 36..1586
/gene="DHCR24"
/gene_synonym="KIAA0018"
/gene_synonym="Nbla03646"
/gene_synonym="seladin-1"
/gene_synonym="SELADIN1"
/codon_start=1
/product="24-dehydrocholesterol reductase"
/protein_id="AAH04375.1"
/db_xref="GeneID:1718"
/db_xref="HGNC:HGNC:2859"
/db_xref="MIM:606418"
/translation="MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSL
IFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSL
RVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELD
DLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSC
GTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDE
AVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRS
IFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMK
CLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEA
RSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYD
KICKAARH"
BASE COUNT 928 a 1151 c 1132 g 991 t
ORIGIN
1 gcgaacccgc agcgcttacc gcgcggcgcc gcaccatgga gcccgccgtg tcgctggccg
61 tgtgcgcgct gctcttcctg ctgtgggtgc gcctgaaggg gctggagttc gtgctcatcc
121 accagcgctg ggtgttcgtg tgcctcttcc tcctgccgct ctcgcttatc ttcgatatct
181 actactacgt gcgcgcctgg gtggtgttca agctcagcag cgctccgcgc ctgcacgagc
241 agcgcgtgcg ggacatccag aagcaggtgc gggaatggaa ggagcagggt agcaagacct
301 tcatgtgcac ggggcgccct ggctggctca ctgtctcact acgtgtcggg aagtacaaga
361 agacacacaa aaacatcatg atcaacctga tggacattct ggaagtggac accaagaaac
421 agattgtccg tgtggagccc ttggtgacca tgggccaggt gactgccctg ctgacctcca
481 ttggctggac tctccccgtg ttgcctgagc ttgatgacct cacagtgggg ggcttgatca
541 tgggcacagg catcgagtca tcatcccaca agtacggcct gttccaacac atctgcactg
601 cttacgagct ggtcctggct gatggcagct ttgtgcgatg cactccgtcc gaaaactcag
661 acctgttcta tgccgtaccc tggtcctgtg ggacgctggg tttcctggtg gccgctgaga
721 tccgcatcat ccctgccaag aagtacgtca agctgcgttt cgagccagtg cggggcctgg
781 aggctatctg tgccaagttc acccacgagt cccagcggca ggagaaccac ttcgtggaag
841 ggctgctcta ctccctggat gaggctgtca ttatgacagg ggtcatgaca gatgaggcag
901 agcccagcaa gctgaatagc attggcaatt actacaagcc gtggttcttt aagcatgtgg
961 agaactatct gaagacaaac cgagagggcc tggagtacat tcccttgaga cactactacc
1021 accgccacac gcgcagcatc ttctgggagc tccaggacat tatccccttt ggcaacaacc
1081 ccatcttccg ctacctcttt ggctggatgg tgcctcccaa gatctccctc ctgaagctga
1141 cccagggtga gaccctgcgc aagctgtacg agcagcacca cgtggtgcag gacatgctgg
1201 tgcccatgaa gtgcctgcag caggccctgc acaccttcca aaacgacatc cacgtctacc
1261 ccatctggct gtgtccgttc atcctgccca gccagccagg cctagtgcac cccaaaggaa
1321 atgaggcaga gctctacatc gacattggag catatgggga gccgcgtgtg aaacactttg
1381 aagccaggtc ctgcatgagg cagctggaga agtttgtccg cagcgtgcat ggcttccaga
1441 tgctgtatgc cgactgctac atgaaccggg aggagttctg ggagatgttt gatggctcct
1501 tgtaccacaa gctgcgagag aagctgggtt gccaggacgc cttccccgag gtgtacgaca
1561 agatctgcaa ggccgccagg cactgagctg gagcccgcct ggagagacag acacgtgtga
1621 gtggtcaggc atcttccctt cactcaagct tggctgcttt cctagatcca cactttcaaa
1681 gagaaacccc tccagaactc ccaccctgac agcccaacac caccttcctc ctggcttcca
1741 gggggcagcc cagtggaatg gaaagaatgt gggatttgga gtcagacaag cctgagtcca
1801 gttccctgtt tagaactcat tagctgtgtg actctgggtg agtcccttaa cccctctgag
1861 cccgggtctc ttcattagtt gaaagggata gtaataccta cttgcaggtt gttgtcatct
1921 gagttgagca ctggtcacat tgaaggtgct gggtaagtgg tagctcttgt tgcttcccgt
1981 tcagcgtcac atctgcagtg gagcctgaaa aggctccaca ttaggtcacc tgtgcacagc
2041 catggctgga atgatgaagg ggatacgctg gagttgccct gccatcgcct ccatcagcca
2101 gacgaggtcc tcacaggaga aggacagctc ttccccaccc tgggatctca ggagggcagc
2161 cacggagtgg ggaggcccca gatgcgctgt gccaaagcca ggtccgaggc caaagttctc
2221 cctgccatcc ttggtgccgt cctgcccctt cctccttcat gcctgggcct gcaggcccac
2281 cccagccacc actgagtcca ctcggagtgc cctgtgttcc tggagaaggc attccagggt
2341 tgaatcttgt cccagcctca gcctgggaca cctaggtgga gagagtggtc tccgctctga
2401 attggatcca ggggacctgg gctcattctt cttggctcac caaccctgca ggcctcatct
2461 ttcccaaaac ccactttgtc ttggtgggag tgggtccgcg ctgctctgca gcaggggctg
2521 gggagtggac agcatcaggt gggaaagtgg agtccaccct catgtttctg taggattctc
2581 accgtggggc tggaagaaaa gagcatcgac ttgatttctc caaccactca tccctctttt
2641 tctttcttcc accactcccc accccagctg tagttaattt cagtgcctta caaatcctaa
2701 gctcagagaa agttccattt ccgttccaga gggaagggaa cctccctagg tccttccctg
2761 gcttgttata acgcaaagct tggttgttta tgcaactcta tcttaagaac tgcccagcct
2821 cagctgaaaa cccgaatctg agaaggaatt gcgtcatgta agggaagctg gaattaaggg
2881 agctgagcca gtcatggttg tggcgtgtga gtcaggagac ctaggtttca gcccctctct
2941 actgtcagcg agctgtgcaa cgtgggcaag tcattgtcct ctgagctgca gtttcctcat
3001 ctgtcacatc gctacagaca agacctccct ggaacccttc tgattgtctt agacactgtg
3061 gttgcaaaac ccacggaaag cctcatttgt gtggaaagtc agaggaaaaa tgatccagtg
3121 gacacttggg gattatctgt cattcaagat ccttccttca accccaaggc cagctcccat
3181 ctcatttcca gaaaggctca tacctggctt gcagggaagc atctgtcttg tcattccagg
3241 tgccagaatc ctctcagagt cattgaaggg tgttcaccca tcccacccaa ggcttggcac
3301 actgccagtg tcttagcagg gtcttgtgag ggctgggggc atccaggcac tcagaaggca
3361 aaggaaccac cctacccatt tggcctctgg agggggcaga agaaagaaag aaacctcatc
3421 ctatatttta caaagcatgt gaattctggc attagctctc ataggagacc catgtgcttc
3481 cttgctcagt gcaaaactga tgattctact tgctgtagat gaatggttaa cacgagctag
3541 ttaaacagtg ccattgtttt gccagtgaag cctccaaccc taagccactg ggacggtggc
3601 cagagatgcc agcagcctct gtcgccctta gtcatataac caaaatccag accttatcca
3661 caacccgggg cttggaaagg aaggtatttt ggaatcacac cctccggtta tgttgctcca
3721 gtaaaatctt gcctggaaag aggcagtctt cttagcatgg tgagctgagt tcatggcttt
3781 tttttgtagc cagtcctgtc cctggccatc catgtgatgg ttttggatgg agttaaactt
3841 gatgccagtg ggcagtgcat gtggaaagta tcagagtaag cctctcccct ccagagccct
3901 gagtttcttg gctgcatgaa ggttttcttt agaatcagaa ttgtagccag tttctttggc
3961 cagaaggatg aatacttgga tattactgaa agggaggggt ggagatgggt gtggcagtgt
4021 atggtgtgtg atttttattt tcttctttgg tcatgggggc caaggagaaa ggcatgaatc
4081 ttccctgtca ggctcttaca gccacaggca ctgtgtctac tgtctggaag acatgtcccc
4141 gtggctgtgg ggccgctgct tctgtttaaa taaaagtggc ctggaaaaaa aaaaaaaaaa
4201 aa
//