LOCUS BC004246 4249 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mutS homolog 6 (E. coli), mRNA (cDNA clone MGC:10498
IMAGE:3629489), complete cds.
ACCESSION BC004246
VERSION BC004246.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4249)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4249)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: m Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504190.
FEATURES Location/Qualifiers
source 1..4249
/db_xref="H-InvDB:HIT000031813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10498 IMAGE:3629489"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4249
/gene="MSH6"
/gene_synonym="HNPCC5"
/gene_synonym="HSAP"
/db_xref="GeneID:2956"
/db_xref="HGNC:HGNC:7329"
/db_xref="MIM:600678"
CDS 53..4135
/gene="MSH6"
/gene_synonym="HNPCC5"
/gene_synonym="HSAP"
/codon_start=1
/product="mutS homolog 6 (E. coli)"
/protein_id="AAH04246.1"
/db_xref="GeneID:2956"
/db_xref="HGNC:HGNC:7329"
/db_xref="MIM:600678"
/translation="MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSP
GGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEG
YPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQ
KGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDK
SEEDNEIESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSD
EISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETK
NTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLV
FMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRV
VRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLG
KFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPG
SQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALS
ALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTL
NNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDL
MVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKII
DFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDT
AFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGI
GRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLK
DCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPF
LELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQ
AGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHA
TAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAV
RLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL"
BASE COUNT 1264 a 829 c 1064 g 1092 t
ORIGIN
1 tgcttttagg agctccgtcc gacagaacgg ttgggccttg ccggctgtcg gtatgtcgcg
61 acagagcacc ctgtacagct tcttccccaa gtctccggcg ctgagtgatg ccaacaaggc
121 ctcggccagg gcctcacgcg aaggcggccg tgccgccgct gcccccgggg cctctccttc
181 cccaggcggg gatgcggcct ggagcgaggc tgggcctggg cccaggccct tggcgcgatc
241 cgcgtcaccg cccaaggcga agaacctcaa cggagggctg cggagatcgg tagcgcctgc
301 tgcccccacc agttgtgact tctcaccggg agatttggtt tgggccaaga tggagggtta
361 cccctggtgg ccttgtctgg tttacaacca cccctttgat ggaacattca tccgcgagaa
421 agggaaatca gtccgtgttc atgtacagtt ttttgatgac agcccaacaa ggggctgggt
481 tagcaaaagg cttttaaagc catatacagg ttcaaaatca aaggaagccc agaagggagg
541 tcatttttac agtgcaaagc ctgaaatact gagagcaatg caacgtgcag acgaagcctt
601 aaataaagac aagattaaga ggcttgaatt ggcagtttgt gatgagccct cagagccaga
661 agaggaagaa gagatggagg taggcacaac ttacgtaaca gataagagtg aagaagataa
721 tgaaattgag agtgaagagg aagtacagcc taagacacaa ggatctaggc gaagtagccg
781 ccaaataaaa aaacgaaggg tcatatcaga ttctgagagt gacattggtg gctctgatgt
841 ggaatttaag ccagacacta aggaggaagg aagcagtgat gaaataagca gtggagtggg
901 ggatagtgag agtgaaggcc tgaacagccc tgtcaaagtt gctcgaaagc ggaagagaat
961 ggtgactgga aatggctctc ttaaaaggaa aagctctagg aaggaaacgc cctcagccac
1021 caaacaagca actagcattt catcagaaac caagaatact ttgagagctt tctctgcccc
1081 tcaaaattct gaatcccaag cccacgttag tggaggtggt gatgacagta gtcgccctac
1141 tgtttggtat catgaaactt tagaatggct taaggaggaa aagagaagag atgagcacag
1201 gaggaggcct gatcaccccg attttgatgc atctacactc tatgtgcctg aggatttcct
1261 caattcttgt actcctggga tgaggaagtg gtggcagatt aagtctcaga actttgatct
1321 tgtcatctgt tacaaggtgg ggaaatttta tgagctgtac cacatggatg ctcttattgg
1381 agtcagtgaa ctggggctgg tattcatgaa aggcaactgg gcccattctg gctttcctga
1441 aattgcattt ggccgttatt cagattccct ggtgcagaag ggctataaag tagcacgagt
1501 ggaacagact gagactccag aaatgatgga ggcacgatgt agaaagatgg cacatatatc
1561 caagtatgat agagtggtga ggagggagat ctgtaggatc attaccaagg gtacacagac
1621 ttacagtgtg ctggaaggtg atccctctga gaactacagt aagtatcttc ttagcctcaa
1681 agaaaaagag gaagattctt ctggccatac tcgtgcatat ggtgtgtgct ttgttgatac
1741 ttcactggga aagtttttca taggtcagtt ttcagatgat cgccattgtt cgagatttag
1801 gactctagtg gcacactatc ccccagtaca agttttattt gaaaaaggaa atctctcaaa
1861 ggaaactaaa acaattctaa agagttcatt gtcctgttct cttcaggaag gtctgatacc
1921 cggctcccag ttttgggatg catccaaaac tttgagaact ctccttgagg aagaatattt
1981 tagggaaaag ctaagtgatg gcattggggt gatgttaccc caggtgctta aaggtatgac
2041 ttcagagtct gattccattg ggttgacacc aggagagaaa agtgaattgg ccctctctgc
2101 tctaggtggt tgtgtcttct acctcaaaaa atgccttatt gatcaggagc ttttatcaat
2161 ggctaatttt gaagaatata ttcccttgga ttctgacaca gtcagcacta caagatctgg
2221 tgctatcttc accaaagcct atcaacgaat ggtgctagat gcagtgacat taaacaactt
2281 ggagattttt ctgaatggaa caaatggttc tactgaagga accctactag agagggttga
2341 tacttgccat actccttttg gtaagcggct cctaaagcaa tggctttgtg ccccactctg
2401 taaccattat gctattaatg atcgtctaga tgccatagaa gacctcatgg ttgtgcctga
2461 caaaatctcc gaagttgtag agcttctaaa gaagcttcca gatcttgaga ggctactcag
2521 taaaattcat aatgttgggt ctcccctgaa gagtcagaac cacccagaca gcagggctat
2581 aatgtatgaa gaaactacat acagcaagaa gaagattatt gattttcttt ctgctctgga
2641 aggattcaaa gtaatgtgta aaattatagg gatcatggaa gaagttgctg atggttttaa
2701 gtctaaaatc cttaagcagg tcatctctct gcagacaaaa aatcctgaag gtcgttttcc
2761 tgatttgact gtagaattga accgatggga tacagccttt gaccatgaaa aggctcgaaa
2821 gactggactt attactccca aagcaggctt tgactctgat tatgaccaag ctcttgctga
2881 cataagagaa aatgaacaga gcctcctgga atacctagag aaacagcgca acagaattgg
2941 ctgtaggacc atagtctatt gggggattgg taggaaccgt taccagctgg aaattcctga
3001 gaatttcacc actcgcaatt tgccagaaga atacgagttg aaatctacca agaagggctg
3061 taaacgatac tggaccaaaa ctattgaaaa gaagttggct aatctcataa atgctgaaga
3121 acggagggat gtatcattga aggactgcat gcggcgactg ttctataact ttgataaaaa
3181 ttacaaggac tggcagtctg ctgtagagtg tatcgcagtg ttggatgttt tactgtgcct
3241 ggctaactat agtcgagggg gtgatggtcc tatgtgtcgc ccagtaattc tgttgccgga
3301 agataccccc cccttcttag agcttaaagg atcacgccat ccttgcatta cgaagacttt
3361 ttttggagat gattttattc ctaatgacat tctaataggc tgtgaggaag aggagcagga
3421 aaatggcaaa gcctattgtg tgcttgttac tggaccaaat atggggggca agtctacgct
3481 tatgagacag gctggcttat tagctgtaat ggcccagatg ggttgttacg tccctgctga
3541 agtgtgcagg ctcacaccaa ttgatagagt gtttactaga cttggtgcct cagacagaat
3601 aatgtcaggt gaaagtacat tttttgttga attaagtgaa actgccagca tactcatgca
3661 tgcaacagca cattctctgg tgcttgtgga tgaattagga agaggtactg caacatttga
3721 tgggacggca atagcaaatg cagttgttaa agaacttgct gagactataa aatgtcgtac
3781 attattttca actcactacc attcattagt agaagattat tctcaaaatg ttgctgtgcg
3841 cctaggacat atggcatgca tggtagaaaa tgaatgtgaa gaccccagcc aggagactat
3901 tacgttcctc tataaattca ttaagggagc ttgtcctaaa agctatggct ttaatgcagc
3961 aaggcttgct aatctcccag aggaagttat tcaaaaggga catagaaaag caagagaatt
4021 tgagaagatg aatcagtcac tacgattatt tcgggaagtt tgcctggcta gtgaaaggtc
4081 aactgtagat gctgaagctg tccataaatt gctgactttg attaaggaat tatagactga
4141 ctacattgga agctttgagt tgacttctga caaaggtggt aaattcagac aacattatga
4201 tctaataaac tttattttta aaaaatgaaa aaaaaaaaaa aaaaaaaaa
//