LOCUS BC004207 1740 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CHK2 checkpoint homolog (S. pombe), mRNA (cDNA clone
MGC:4081 IMAGE:3532866), complete cds.
ACCESSION BC004207
VERSION BC004207.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1740)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1740)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 31, 2003 this sequence version replaced BC004207.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 11 Row: f Column: 17.
FEATURES Location/Qualifiers
source 1..1740
/db_xref="H-InvDB:HIT000031781"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4081 IMAGE:3532866"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1740
/gene="CHEK2"
/gene_synonym="CDS1"
/gene_synonym="CHK2"
/gene_synonym="HuCds1"
/gene_synonym="LFS2"
/gene_synonym="PP1425"
/db_xref="GeneID:11200"
/db_xref="HGNC:HGNC:16627"
/db_xref="MIM:604373"
CDS 28..1659
/gene="CHEK2"
/gene_synonym="CDS1"
/gene_synonym="CHK2"
/gene_synonym="HuCds1"
/gene_synonym="LFS2"
/gene_synonym="PP1425"
/codon_start=1
/product="CHK2 checkpoint homolog (S. pombe)"
/protein_id="AAH04207.1"
/db_xref="GeneID:11200"
/db_xref="HGNC:HGNC:16627"
/db_xref="MIM:604373"
/translation="MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTS
TMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDG
FANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYI
EDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRD
EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEI
LKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLA
VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLA
PEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPE
VWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTAL
PQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL"
BASE COUNT 519 a 370 c 411 g 440 t
ORIGIN
1 ggctccaggt gggctcacgc ggtcgtgatg tctcgggagt cggatgttga ggctcagcag
61 tctcatggca gcagtgcctg ttcacagccc catggcagcg ttacccagtc ccaaggctcc
121 tcctcacagt cccagggcat atccagctcc tctaccagca cgatgccaaa ctccagccag
181 tcctctcact ccagctctgg gacactgagc tccttagaga cagtgtccac tcaggaactc
241 tattctattc ctgaggacca agaacctgag gaccaagaac ctgaggagcc tacccctgcc
301 ccctgggctc gattatgggc ccttcaggat ggatttgcca atcttgaatg tgtgaatgac
361 aactactggt ttgggaggga caaaagctgt gaatattgct ttgatgaacc actgctgaaa
421 agaacagata aataccgaac atacagcaag aaacactttc ggattttcag ggaagtgggt
481 cctaaaaact cttacattgc atacatagaa gatcacagtg gcaatggaac ctttgtaaat
541 acagagcttg tagggaaagg aaaacgccgt cctttgaata acaattctga aattgcactg
601 tcactaagca gaaataaagt ttttgtcttt tttgatctga ctgtagatga tcagtcagtt
661 tatcctaagg cattaagaga tgaatacatc atgtcaaaaa ctcttggaag tggtgcctgt
721 ggagaggtaa agctggcttt cgagaggaaa acatgtaaga aagtagccat aaagatcatc
781 agcaaaagga agtttgctat tggttcagca agagaggcag acccagctct caatgttgaa
841 acagaaatag aaattttgaa aaagctaaat catccttgca tcatcaagat taaaaacttt
901 tttgatgcag aagattatta tattgttttg gaattgatgg aagggggaga gctgtttgac
961 aaagtggtgg ggaataaacg cctgaaagaa gctacctgca agctctattt ttaccagatg
1021 ctcttggctg tgcagtacct tcatgaaaac ggtattatac accgtgactt aaagccagag
1081 aatgttttac tgtcatctca agaagaggac tgtcttataa agattactga ttttgggcac
1141 tccaagattt tgggagagac ctctctcatg agaaccttat gtggaacccc cacctacttg
1201 gcgcctgaag ttcttgtttc tgttgggact gctgggtata accgtgctgt ggactgctgg
1261 agtttaggag ttattctttt tatctgcctt agtgggtatc cacctttctc tgagcatagg
1321 actcaagtgt cactgaagga tcagatcacc agtggaaaat acaacttcat tcctgaagtc
1381 tgggcagaag tctcagagaa agctctggac cttgtcaaga agttgttggt agtggatcca
1441 aaggcacgtt ttacgacaga agaagcctta agacacccgt ggcttcagga tgaagacatg
1501 aagagaaagt ttcaagatct tctgtctgag gaaaatgaat ccacagctct accccaggtt
1561 ctagcccagc cttctactag tcgaaagcgg ccccgtgaag gggaagccga gggtgccgag
1621 accacaaagc gcccagctgt gtgtgctgct gtgttgtgaa ctccgtggtt tgaacacgaa
1681 agaaatgtac cttctttcac tctgtcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
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