LOCUS BC003573 1442 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens farnesyl-diphosphate farnesyltransferase 1, mRNA (cDNA
clone MGC:2200 IMAGE:3538137), complete cds.
ACCESSION BC003573
VERSION BC003573.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1442)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1442)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: p Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 67089146.
FEATURES Location/Qualifiers
source 1..1442
/db_xref="H-InvDB:HIT000031611"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2200 IMAGE:3538137"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1442
/gene="FDFT1"
/gene_synonym="DGPT"
/gene_synonym="ERG9"
/gene_synonym="SQS"
/gene_synonym="SS"
/db_xref="GeneID:2222"
/db_xref="HGNC:HGNC:3629"
/db_xref="MIM:184420"
CDS 70..1323
/gene="FDFT1"
/gene_synonym="DGPT"
/gene_synonym="ERG9"
/gene_synonym="SQS"
/gene_synonym="SS"
/codon_start=1
/product="farnesyl-diphosphate farnesyltransferase 1"
/protein_id="AAH03573.1"
/db_xref="GeneID:2222"
/db_xref="HGNC:HGNC:3629"
/db_xref="MIM:184420"
/translation="MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCY
KYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHS
FLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDK
HVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIR
DYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITY
LSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAV
KAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVML
LAALSWQYLTTLSQVTEDYVQTGEH"
BASE COUNT 409 a 346 c 355 g 332 t
ORIGIN
1 gccggccggt gagcgcctgg ggaccgcaga ggtgagagtc gcgcccggga gtccgccgcc
61 tgcgccagga tggagttcgt gaaatgcctt ggccaccccg aagagttcta caacctggtg
121 cgcttccgga tcgggggcaa gcggaaggtg atgcccaaga tggaccagga ctcgctcagc
181 agcagcctga aaacttgcta caagtatctc aatcagacca gtcgcagttt cgcagctgtt
241 atccaggcgc tggatgggga aatgcgcaat gcagtgtgca tattttatct ggttctccga
301 gctctggaca cactggaaga tgacatgacc atcagtgtgg aaaagaaggt cccgctgtta
361 cacaactttc actctttcct ttaccaacca gactggcggt tcatggagag caaggagaag
421 gatcgccagg tgctggagga cttcccaacg atctcccttg agtttagaaa tctggctgag
481 aaataccaaa cagtgattgc cgacatttgc cggagaatgg gcattgggat ggcagagttt
541 ttggataagc atgtgacctc tgaacaggag tgggacaagt actgccacta tgttgctggg
601 ctggtcggaa ttggcctttc ccgtcttttc tcagcctcag agtttgaaga ccccttagtt
661 ggtgaagata cagaacgtgc caactctatg ggcctgtttc tgcagaaaac aaacatcatc
721 cgtgactatc tggaagacca gcaaggagga agagagttct ggcctcaaga ggtttggagc
781 aggtatgtta agaagttagg ggattttgct aagccggaga atattgactt ggccgtgcag
841 tgcctgaatg aacttataac caatgcactg caccacatcc cagatgtcat cacctacctt
901 tcgagactca gaaaccagag tgtgtttaac ttctgtgcta ttccacaggt gatggccatt
961 gccactttgg ctgcctgtta taataaccag caggtgttca aaggggcagt gaagattcgg
1021 aaagggcaag cagtgaccct catgatggat gccaccaata tgccagctgt caaagccatc
1081 atatatcagt atatggaaga gatttatcat agaatccccg actcagaccc atcttctagc
1141 aaaacaaggc agatcatctc caccatccgg acgcagaatc ttcccaactg tcagctgatt
1201 tcccgaagcc actactcccc catctacctg tcgtttgtca tgcttttggc tgccctgagc
1261 tggcagtacc tgaccactct ctcccaggta acagaagact atgttcagac tggagaacac
1321 tgatcccaaa tttgtccata gctgaagtcc accataaagt ggatttactt tttttcttta
1381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaacctcg
1441 gg
//