LOCUS BC003143 2710 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dual specificity phosphatase 6, mRNA (cDNA clone
MGC:3789 IMAGE:2906126), complete cds.
ACCESSION BC003143
VERSION BC003143.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2710)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2710)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: j Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42764682.
FEATURES Location/Qualifiers
source 1..2710
/db_xref="H-InvDB:HIT000031462"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3789 IMAGE:2906126"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2710
/gene="DUSP6"
/gene_synonym="MKP3"
/gene_synonym="PYST1"
/db_xref="GeneID:1848"
/db_xref="HGNC:HGNC:3072"
/db_xref="MIM:602748"
CDS 349..1494
/gene="DUSP6"
/gene_synonym="MKP3"
/gene_synonym="PYST1"
/codon_start=1
/product="dual specificity phosphatase 6"
/protein_id="AAH03143.1"
/db_xref="GeneID:1848"
/db_xref="HGNC:HGNC:3072"
/db_xref="MIM:602748"
/translation="MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQEL
YESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESS
SDWNENTGGESLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSP
PLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGC
AKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAI
SFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNF
NFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST"
BASE COUNT 694 a 635 c 665 g 716 t
ORIGIN
1 cttggaggga gggattagaa gccgctagac tttttttcct cccctctcag tagcacggag
61 tccgaattaa ttggatttca ttcactgggg aggaacaaaa actatctggg cagcttcatt
121 gagagagatt cattgacact aagagccagc ggctgcagct gggtgcagag agaacctccg
181 gctttacttc tgtctcgtct gccccaaccg ctagcctcgg cttgggtaag gcgaggcgga
241 attaaacccc gctccgagag cggcagcttc gcgcgcggtg cgctcggcct atgcctgccc
301 cgaggggcgt ctggtaggca ccccgccctc tcccgcagct cgacccccat gatagatacg
361 ctcagacccg tgcccttcgc gtcggaaatg gcgatcagca agacggtggc gtggctcaac
421 gagcagctgg agctgggcaa cgagcggctg ctgctgatgg actgccggcc gcaggagcta
481 tacgagtcgt cgcacatcga gtcggccatc aacgtggcca tcccgggcat catgctgcgg
541 cgcctgcaga agggtaacct gccggtgcgc gcgctcttca cgcgcggcga ggaccgggac
601 cgcttcaccc ggcgctgtgg caccgacaca gtggtgctct acgacgagag cagcagcgac
661 tggaacgaga atacgggcgg cgagtcgttg ctcgggctgc tgctcaagaa gctcaaggac
721 gagggctgcc gggcgttcta cctggaaggt ggcttcagta agttccaagc cgagttctcc
781 ctgcattgcg agaccaatct agacggctcg tgtagcagca gctcgccgcc gttgccagtg
841 ctggggctcg ggggcctgcg gatcagctct gactcttcct cggacatcga gtctgacctt
901 gaccgagacc ccaatagtgc aacagactcg gatggtagtc cgctgtccaa cagccagcct
961 tccttcccag tggagatctt gcccttcctc tacttgggct gtgccaaaga ctccaccaac
1021 ttggacgtgt tggaggaatt cggcatcaag tacatcttga acgtcacccc caatttgccg
1081 aatctctttg agaacgcagg agagtttaaa tacaagcaaa tccccatctc ggatcactgg
1141 agccaaaacc tgtcccagtt tttccctgag gccatttctt tcatagatga agcccggggc
1201 aagaactgtg gtgtcttggt acattgcttg gctggcatta gccgctcagt cactgtgact
1261 gtggcttacc ttatgcagaa gctcaatctg tcgatgaacg atgcctatga cattgtcaaa
1321 atgaaaaaat ccaacatatc ccctaacttc aacttcatgg gtcagctgct ggacttcgag
1381 aggacgctgg gactcagcag cccatgtgac aacagggttc cagcacagca gctgtatttt
1441 accacccctt ccaaccagaa tgtataccag gtggactctc tgcaatctac gtgaaagacc
1501 ccacatccct ccttgctgga atgtgtctgg cccttcagca gtttctcttg gcagcatcag
1561 ctgggctgct ttctttgtgt gtggccccag gtgtcaaaat gacaccagct gtctgtacta
1621 gacaaggtta ccaagtgcgg aattggttaa tactaacaga gagatttgct ccattctctt
1681 tggaataaca ggacatgctg tatagataca ggcagtaggt ttgctctgta cccatgtgta
1741 cagcctaccc atgcagggac tgggattcga ggacttccag gcgcataggg tagaaccaaa
1801 tgatagggta ggagcatgtg ttctttaggg ccttgtaagg ctgtttcctt ttgcatctgg
1861 aactgactat ataattgtct tcaatgaaga ctaattcaat tttgcatata gaggagccaa
1921 agagagattt cagctctgta tttgtggtat cagtttggaa aaaaaaatct gatactccat
1981 ttgattattg taaatatttg atcttgaatc acttgacagt gtttgtttga attgtgtttg
2041 ttttttcctt tgatgggctt aaaagaaatt atccaaaggg agaaagagca gtatgccact
2101 tcttaaaaca gaacaaaaca aaaaaagaaa attgtgctct tttctaatcc aaagggtata
2161 tttgcagcat gcttgacttt accaattctg atgacatctt tacggacact attatcacta
2221 agaccttgtt atggcgaagt ctttagtctt tttcatgtat tttcctcatg attttttctc
2281 tttatgtagt ttgactatgc cttacctttg taaatatttt tgcttgtgtt gtcgcaaagg
2341 ggataatctg ggaaagacac caaatcatgg gctcacttta aaaaaagaaa gaataaaaaa
2401 accttcagct gtgctaaaca gtatattacc tctgtataaa attcttcagg gagtgtcacc
2461 tcaaatgcaa tactttgggt tggtttcttt cctttaaaaa aatttgtata aaactggaag
2521 tgtgtgtgtg tgagcatggg tacccatttg ataagagaaa tgcatttgat tgtgaagaag
2581 ggagagttaa attctccatt atgttcgtgg tgtaaagttt agagctggaa tttattataa
2641 gaatgtaaaa ccttaaatta ttaataaata actattttgg ctattgaaaa aaaaaaaaaa
2701 aaaaaaaaaa
//