LOCUS BC003122 3408 bp mRNA linear HUM 27-JAN-2004
DEFINITION Homo sapiens Cdk5 and Abl enzyme substrate 2, mRNA (cDNA clone
IMAGE:3357127), partial cds.
ACCESSION BC003122
VERSION BC003122.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3408)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3408)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: m Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..3408
/db_xref="H-InvDB:HIT000086217"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3357127"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..3408
/gene="CABLES2"
/gene_synonym="C20orf150"
/gene_synonym="dJ908M14.2"
/gene_synonym="ik3-2"
/db_xref="GeneID:81928"
CDS <1..979
/gene="CABLES2"
/gene_synonym="C20orf150"
/gene_synonym="dJ908M14.2"
/gene_synonym="ik3-2"
/codon_start=2
/product="CABLES2 protein"
/protein_id="AAH03122.1"
/db_xref="GeneID:81928"
/translation="RHKGLKKTHFIKNMRQYDTRNSRIVLICAKRSLCAAFSVLPYGE
GLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTH
KSDSHGLLPTPRPSVPRTLPGPRHKPAPTKSAPASTELGSDVGDTLEYNPNLLDDPQW
PCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLSKIRSLKREMRS
LSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVKQ
LIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF"
misc_feature 626..796
/gene="CABLES2"
/gene_synonym="C20orf150"
/gene_synonym="dJ908M14.2"
/gene_synonym="ik3-2"
/note="CYCLIN; Region: Cyclin box fold. Protein binding
domain functioning in cell-cycle and transcription
control. Present in cyclins, TFIIB and Retinoblastoma
(RB).The cyclins consist of 8 classes of cell cycle
regulators that regulate cyclin dependent kinases (CDKs).
TFIIB is a transcription factor that binds the TATA box.
Cyclins, TFIIB and RB contain 2 copies of the domain"
/db_xref="CDD:cd00043"
BASE COUNT 847 a 956 c 817 g 788 t
ORIGIN
1 gagacataaa ggcctgaaga agacccactt catcaagaac atgaggcagt acgacaccag
61 gaacagcagg atcgtgctca tctgtgccaa gcggtccctg tgcgcggcct tctcggtcct
121 gccctatggg gaaggcctgc ggatcagtga cctgagggtg gacagccaga agcagaggca
181 cccgtccggc ggcgtctctg tgtcttccga gatggtcttt gagctagaag gtgtggagct
241 aggagcagac gggaaggtcg tgtcttatgc gaagttcctg tatcccacca acgccctggt
301 cacacacaag agtgacagcc atggcctgct gcccacacct cggcccagtg tcccccggac
361 tctgccaggg ccaagacata aacctgcccc caccaagtcg gcaccagcca gcacagaact
421 agggagtgac gtgggggaca ccctggagta caaccccaac ctcctggatg acccgcagtg
481 gccctgcggc aagcacaaac gtgtcctcat ctttgcgtcg tacatgacca cagtgataga
541 atacgtgaag ccctcagacc tcaaaaagga catgaacgag accttcaggg agaagttccc
601 ccatgtcaaa ctgacgctga gcaaaatcag gagcttaaag cgggagatgc ggagcctgtc
661 ggaggagtgc agcctggagc ccgtgacggt ggccatggcc tacgtgtact ttgagaagct
721 ggtcctgcag ggcaagctca gcaaacagaa ccgcaagctg tgcgctggcg cctgcgtgct
781 gctggctgcc aagatcagca gtgacctgcg caagagcggc gtgaagcagc tcatcgataa
841 gttagaagaa aggtttcgat tcaacaggcg cgacctgata gggtttgagt tcacagtgct
901 cgtggccttg gagctggccc tgtatcttcc cgagaaccaa gtgttacctc attacaggcg
961 cctcacccag cagttctagc agaggcccca cagaaggctc agggcaccga ggtgcacttg
1021 ccggcctggg aggtgtccca ctgaagcccc gcgcctcctc ctgccagcac ccccagcacc
1081 tgctagcagg aggcacctgg cctccgctgg tgcagctttc ctttttgcct ctttgccatt
1141 tccttggaaa gagacgtcgc tttcatcccc aagtgcaccg tccctccgag gggatttctg
1201 agaattctcc tgcattttta cataaactaa atgtgaggtt tgttactggt atttttttca
1261 cgtgcctgag accagcctgg taccaggacc ttttgttcac agcgtgcagc agcgagccgg
1321 ctgcagtgtg tctcccctgg cctcgccttc tgcaaaccac cgcagccacc acagcgtcag
1381 ggtggagatc tgggtttcta gacctcactg aacacactgg aatggctgag tttaacttat
1441 ttaggcattc atcttggaga tgtggttttt cgggttcccc agcagcatct cccgacacca
1501 actgtgccgc tggctccctg ccacctgaag ccgagctcct ccagagcttt ctccgcccac
1561 ctcactgcat cccaagtgga gcttttggtg tccagttagg ccagcgggag cagtctcctg
1621 atttattttg atctcattct tggactcttg gacctctctg ttcttcaagc atcgtgtcac
1681 tgtgaaatcc taacgcccct gtgtcctaca gaccgacggc acaacagaca gctgcccatc
1741 ccatgccatg ctctaccctc tgcctctcac caggagacac tctgggcctc caggacaatt
1801 gctgcttgcc ggctcttatt tttctaagca atattgtgat ggagaaaaat aacatattta
1861 ttgggatttg gttttttggg tctttttttt ttaagggaac aaaaaatggt taaatgaggt
1921 ctgctgaagt tgacttgaaa acacacttga ccctcaggca ggagggcact gaccacaccc
1981 cacacaacct caaagggtca gtgcgtcagt gccttttctt ctgaggcagg aaacaggtgc
2041 catcttggcc acctcggcca gggcagccca ccatgctaaa aggaccccaa atggtggtcg
2101 ttgtcccttc tgtgcaggcc agcagggccc catctctagt ttttccacgt ctgtctgaag
2161 ttcttgcaac aaattctgca tggtccagcg ctccagctag ctgcctcatc aaaaacactg
2221 aataaccaag gactgctgag tttttcttca tggggggtca gctggtctca aaactggcca
2281 ctgcctcagc caccaagctt tttcctacca ctaccttata aacctgcctg gccctggagg
2341 ggctctggga cgactttgtc tctagcccat taatacaata catcctatgc tttctgtgca
2401 gactggtgct tccgcagaaa ggagatgcca attctgctat cacagaactc caccagcaac
2461 tccacccgac cccagcagtg gtgcaggaca gctgccagca cccacctggc cctcctcctt
2521 ttccacagcc actcactggg gccaccaaaa cccagagatg gcaggtgtgt gggacagact
2581 ggaggatgag gacaaaccaa agcctttgtt ctttcttatt gtggagcgtc cccttccatc
2641 aagcagcctg ccctcaagcc aaggatcatc ccctggaacc cagtatgcac ccagagggga
2701 ctcaacttca aagctgctcc accatgctgg gtcccaggca gctttcctct gaaaagcaac
2761 ctctcctgcc acccagatcc catctcaaga gctcgcccat gttacgagca tgtaaaggac
2821 tgacttccta gtaactgttg cagtttacaa cctgccctcc agggacacgt ctccatggtt
2881 ttttctacac atgaatgcga gaaatggctg ataagcacag taatttaaga ttgcgtattc
2941 atgtagtgag atttagtcat taaccaaccc ggtctttgtg atgtgtgaag ccttcccttc
3001 agttatgtcc catttttatg atgccaaaag ctgccactgt gtggtattcg aggattattg
3061 caacaaagcc agtagttaaa ccaaactaca gtctcagcct gtcattctct agaacacatc
3121 caggtgtcgg agctaaggtg ttcagctcgg ctgtgactat acagaaccag gcctggcgtt
3181 gcttccgcac cggtagcagt tgtggatgtc agtgtgcata agcaagtatc tgacctcaga
3241 atgtttgagt tattttgtct tagatatctg tttttaaatg gataatgtat ttgtccttta
3301 aacctcagtt ttgcaataaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa accccggg
//