LOCUS BC003112 2046 bp mRNA linear HUM 03-NOV-2008
DEFINITION Homo sapiens neurofibromin 2 (merlin), mRNA (cDNA clone MGC:2241
IMAGE:3537045), complete cds.
ACCESSION BC003112
VERSION BC003112.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2046)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2046)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: n Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32967513.
FEATURES Location/Qualifiers
source 1..2046
/db_xref="H-InvDB:HIT000031440"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2241 IMAGE:3537045"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2046
/gene="NF2"
/gene_synonym="ACN"
/gene_synonym="BANF"
/gene_synonym="SCH"
/db_xref="GeneID:4771"
/db_xref="HGNC:HGNC:7773"
/db_xref="MIM:607379"
CDS 273..1796
/gene="NF2"
/gene_synonym="ACN"
/gene_synonym="BANF"
/gene_synonym="SCH"
/codon_start=1
/product="neurofibromin 2 (merlin)"
/protein_id="AAH03112.2"
/db_xref="GeneID:4771"
/db_xref="HGNC:HGNC:7773"
/db_xref="MIM:607379"
/translation="MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEVKKQIL
DEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHI
YDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCI
GNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERR
LLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAI
RTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEI
ATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSK
HLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQGRRPICI"
BASE COUNT 576 a 511 c 587 g 372 t
ORIGIN
1 tcccggagtg ccgggtcgcg cctgcaccga aggtcccggc tcctgtgccc tccctgcagc
61 cgtcagggcc cgtcccccaa ctcccctttc cgctcaggca gggtcctcgc ggcccatgct
121 ggccgctggg gacccgcgca gcccagaccg ttcccgggcc ggccagccgg ccaccatggt
181 ggccctgagg cctgtgcagc aactccaggg gggctaaagg gctcagagtg caggccgtgg
241 ggcgcgaggg tcccgggcct gagccccgcg ccatggccgg ggccatcgct tcccgcatga
301 gcttcagctc tctcaagagg aagcaaccca agacgttcac cgtgaggatc gtcaccatgg
361 acgccgagat ggagttcaat tgcgaggtaa agaagcagat tttagatgaa aagatctact
421 gccctcctga ggcttctgtg ctcctggctt cttacgccgt ccaggccaag tatggtgact
481 acgaccccag tgttcacaag cggggatttt tggcccaaga ggaattgctt ccaaaaaggg
541 taataaatct gtatcagatg actccggaaa tgtgggagga gagaattact gcttggtacg
601 cagagcaccg aggccgagcc agggatgaag ctgaaatgga atatctgaag atagctcagg
661 acctggagat gtacggtgtg aactactttg caatccggaa taaaaagggc acagagctgc
721 tgcttggagt ggatgccctg gggcttcaca tttatgaccc tgagaacaga ctgaccccca
781 agatctcctt cccgtggaat gaaatccgaa acatctcgta cagtgacaag gagtttacta
841 ttaaaccact ggataagaaa attgatgtct tcaagtttaa ctcctcaaag cttcgtgtta
901 ataagctgat tctccagcta tgtatcggga accatgatct atttatgagg agaaggaaag
961 ccgattcttt ggaagttcag cagatgaaag cccaggccag ggaggagaag gctagaaagc
1021 agatggagcg gcagcgcctc gctcgagaga agcagatgag ggaggaggct gaacgcacga
1081 gggatgagtt ggagaggagg ctgctgcaga tgaaagaaga agcaacaatg gccaacgaag
1141 cactgatgcg gtctgaggag acagctgacc tgttggctga aaaggcccag atcaccgagg
1201 aggaggcaaa acttctggcc cagaaggccg cagaggctga gcaggaaatg cagcgcatca
1261 aggccacagc gattcgcacg gaggaggaga agcgcctgat ggagcagaag gtgctggaag
1321 ccgaggtgct ggcactgaag atggctgagg agtcagagag gagggccaaa gaggcagatc
1381 agctgaagca ggacctgcag gaagcacgcg aggcggagcg aagagccaag cagaagctcc
1441 tggagattgc caccaagccc acgtacccgc ccatgaaccc aattccagca ccgttgcctc
1501 ctgacatacc aagcttcaac ctcattggtg acagcctgtc tttcgacttc aaagatactg
1561 acatgaagcg gctttccatg gagatagaga aagaaaaagt ggaatacatg gaaaagagca
1621 agcatctgca ggagcagctc aatgaactca agacagaaat cgaggccttg aaactgaaag
1681 agagggagac agctctggat attctgcaca atgagaactc cgacaggggt ggcagcagca
1741 agcacaatac cattaaaaag cctcaagccc aaggcagaag acctatctgc atttgagccc
1801 tcaaacttcc tctccatagg ctgagcagag atgtggtcag agtgaactca cattggaaca
1861 gtacactcac ggcaccctgg agaggagcgg tcactggttg ctgagtgaat taaccgaatg
1921 tttgctgctt ttctcctgca acagttcatt attcctccag catgcctagg cagtggagag
1981 aatgtatttt gcccaataat aaaatgacat cctgcctcta aaaaaaaaaa aaaaaaaaaa
2041 aaaaaa
//