LOCUS BC003009 2028 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 1 (importin alpha 5), mRNA (cDNA
clone MGC:4009 IMAGE:2822859), complete cds.
ACCESSION BC003009
VERSION BC003009.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2028)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2028)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: f Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504894.
FEATURES Location/Qualifiers
source 1..2028
/db_xref="H-InvDB:HIT000031356"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4009 IMAGE:2822859"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2028
/gene="KPNA1"
/gene_synonym="IPOA5"
/gene_synonym="NPI-1"
/gene_synonym="RCH2"
/gene_synonym="SRP1"
/db_xref="GeneID:3836"
/db_xref="HGNC:HGNC:6394"
/db_xref="MIM:600686"
CDS 178..1794
/gene="KPNA1"
/gene_synonym="IPOA5"
/gene_synonym="NPI-1"
/gene_synonym="RCH2"
/gene_synonym="SRP1"
/codon_start=1
/product="karyopherin alpha 1 (importin alpha 5)"
/protein_id="AAH03009.1"
/db_xref="GeneID:3836"
/db_xref="HGNC:HGNC:6394"
/db_xref="MIM:600686"
/translation="MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQL
FKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSA
TQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL
QTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQ
LFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACW
ALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVI
LNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA
EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENI
LRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTED
EDSSIAPQVDLNQQQYIFQQCEAPMEGFQL"
BASE COUNT 575 a 441 c 510 g 502 t
ORIGIN
1 gccggctgag ctgagtctcg ctgctcggtg cgaggcggcg gagagcgagg cctggtgagc
61 accgccgagg cgcgggccag ctcttcgagg ttgtgcgcgg gagtggcacg gcgggcgggc
121 gagcgagggg ctaacttcag cggtggcacc gggatcggtt gccttgagcc tgaaatcatg
181 accaccccag gaaaagagaa ctttcgcctg aaaagttaca agaacaaatc tctgaatccc
241 gatgagatgc gcaggaggag ggaggaagaa ggactgcagt tacgaaagca gaaaagagaa
301 gagcagttat tcaagcggag aaatgttgct acagcagaag aagaaacaga agaagaagtt
361 atgtcagatg gaggctttca tgaggctcag attaataaca tggagatggc accaggtggt
421 gtcatcactt ctgacatgat tgaaatgata ttttccaaaa gcccagagca acagctttca
481 gcaacacaga aattcaggaa gctgctttca aaagaaccta accctcctat tgatgaagtt
541 atcagcacac caggagtagt ggccaggttt gtggagttcc tcaaacgaaa agagaattgt
601 acactgcagt ttgaatcagc ttgggtactg acaaatattg cttcaggaaa ttctcttcag
661 acccgaattg tgattcaggc aggagctgtg cccatcttca tagagttgct cagctcagag
721 tttgaagatg tccaggaaca ggcagtctgg gctcttggca acattgctgg agatagtacc
781 atgtgcaggg actatgtctt agactgcaat atccttcccc ctcttttgca gttattttca
841 aagcaaaacc gcctgaccat gacccggaat gcagtatggg ctttgtctaa tctctgtaga
901 gggaaaagtc cacctccaga atttgcaaag gtttctccat gtctgaatgt gctttcctgg
961 ttgctgtttg tcagtgacac tgatgtactg gctgatgcct gctgggccct ctcatatcta
1021 tcagatggac ccaatgataa aattcaagcg gtcatcgatg cgggagtatg taggagactt
1081 gtggaactgc tgatgcataa tgattataaa gtggtttctc ctgctttgcg agctgtggga
1141 aacattgtca caggggatga tattcagaca caggtaattc tgaattgctc agctctgcag
1201 agtttattgc atttgctgag tagcccaaag gaatctatca aaaaggaagc atgttggacg
1261 atatctaata ttacagctgg aaatagggca cagatccaga ctgtgataga tgccaacatt
1321 ttcccagccc tcattagtat tttacaaact gctgaatttc ggacaagaaa agaagcagct
1381 tgggccatca caaatgcaac ttctggagga tcagctgaac agatcaagta cctagtagaa
1441 ctgggttgta tcaagccgct ctgtgatctc ctcacggtca tggactctaa gattgtacag
1501 gttgccctaa atggcttgga aaatatcctg aggcttggag aacaggaagc caaaaggaat
1561 ggcactggca ttaaccctta ctgtgctttg attgaagaag cttatggtct ggataaaatt
1621 gagttcttac agagtcatga aaaccaggag atctaccaaa aggcctttga tcttattgag
1681 cattacttcg ggaccgaaga tgaagacagc agcattgcac cccaggttga ccttaaccag
1741 cagcagtaca tcttccaaca gtgtgaggct cctatggaag gtttccagct ttgaagcaat
1801 actctgcttt cacgttcctg tgtcagacca ggctacccag tcgagtcctc ttgtggagcc
1861 cacagtcctc atggagctaa cttctcaaat gttttccata atactgtttg cgctcatttg
1921 cttgccttgc gcacctgctc tcttacacac atctggaaaa cctccggctc tctgtggtgg
1981 aatacccttc taataaaagg gtaaccagat aaaaaaaaaa aaaaaaaa
//